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The map label for this gene is ttuD2 [H]

Identifier: 17545205

GI number: 17545205

Start: 522751

End: 524049

Strand: Direct

Name: ttuD2 [H]

Synonym: RSc0486

Alternate gene names: 17545205

Gene position: 522751-524049 (Clockwise)

Preceding gene: 17545203

Following gene: 17545206

Centisome position: 14.07

GC content: 73.67

Gene sequence:

>1299_bases
GTGAAGCTGGACCGCGCCGCCGCCCGCGCCCTGCTGCTGGAGAGCTACGCGGCGGCCGTCGCCGCGGCGGACCCGCTCAA
GATCGTCGCCGGCTTCCTGCCGCCGCCGCATGCCGGTGGCCGGACGCTGGTGGTCGGGGCCGGCAAGGCGGCCGCGTCGA
TGGCGCTGGCGGTTGAGCGGGCCTACGCCGGCCGCGCACAGATCGAAGGGCTGGTCGTCACGCGCTATGCGCACGGGTTG
CCGACCGATCACATCCGCGTGATCGAAGCCGGCCACCCGGTGCCGGACGAGGCGGGCGAGCAGGCGGCGCAGGCCATTTT
CGATCGCGTGTCGGCGCTGACCGAACACGACCGGCTGATCGTGCTGGTGTCCGGCGGCGGCTCGAGCCTGCTGTCGCTGC
CGGCCGAGGGCGTTCCCATGGCCGACCTCAAGGCCGTGACACGCGAGCTGCTGCGCTGCGGCGCGCCGATCACCGACATG
AACATCGTGCGCAAGCACCTGTCGCGCATCCAGGGCGGCCGCCTGGCCGCGGCATCCCGCGCGCCGGTGACCACGCTGAT
CGTCTCCGACGTGGCCGGCGATGACCCGAGCGCGATCGCCAGCGGCCCCACCGTGCCCGACCCGAGCACCTACGCCGACG
CGCTGGCCATTCTCGCGCGCTGGGGCGCACAGGCGCCCGAATCGGTGCGCGCGCACCTGGAGCGCGGCGCGCGCGGCGAG
ATCGCCGAGACGCCCAAGCCGGGCGATGCCTGCTTTGCGCGGGTGGCCAACCATGTCATCGCCACCGCGCAGCAGAGCCT
GGTGGCGGGGGCGCAGGTCTTCGCGGCGCACGGCATCCACACGGCCATCCTGGGGGATACCGTCACCGGCGAGGCGCGCG
AGGTCGCCCAGGTGTACGGCGCGCTCGCGCGGCAGGTCCGCCGGCACGGCACGCCGTTCGCGGCGCCCGTCGCGCTGGTC
TCCGGCGGTGAATGCACGGTGACTCTCCCGCCGGGCCTGACCGGTGGCCGGGGCGGCCGCTGCGCCGAATTCCTGCTGTC
GCTGGGGATCGCGCTGGAAGACATGGGCGATGTCTATGCGCTGGCGGCCGACACCGACGGTATCGACGGTTCGGAGGGCA
ATGCGGGCGCCGTGCTCGATCCGCAGTCCATCGGACGCGCCGCCGCGCGCGGTGTTGCCGCCCGCGCCGCGCTGGACGCG
CACGACGCCTATGGCTTCTTCGCCGCCGCCGGCGACCTGATCGTCACCGGCCCGACGCGCACCAATGTCAACGACTACCG
CGTCATCCTGATTCTCTGA

Upstream 100 bases:

>100_bases
GCGTGTTGGGCGCCGGGCCGGCCCATGCGCCGCTCACGCGCGACATCGGCGGCACCGCCGGCACGGCGGACCTGGGCCGT
GCGATCGCGGAGGCGCTGGC

Downstream 100 bases:

>100_bases
ATTTCATTTCTTTCTGTCTTTTTCTCTTCACGCATCATGATCGATACCCTGACCATCGTCCGCCCTGATGACTGGCACCT
GCACCTGCGCGATGGCGACG

Product: hydroxypyruvate reductase oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKLDRAAARALLLESYAAAVAAADPLKIVAGFLPPPHAGGRTLVVGAGKAAASMALAVERAYAGRAQIEGLVVTRYAHGL
PTDHIRVIEAGHPVPDEAGEQAAQAIFDRVSALTEHDRLIVLVSGGGSSLLSLPAEGVPMADLKAVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPVTTLIVSDVAGDDPSAIASGPTVPDPSTYADALAILARWGAQAPESVRAHLERGARGE
IAETPKPGDACFARVANHVIATAQQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYGALARQVRRHGTPFAAPVALV
SGGECTVTLPPGLTGGRGGRCAEFLLSLGIALEDMGDVYALAADTDGIDGSEGNAGAVLDPQSIGRAAARGVAARAALDA
HDAYGFFAAAGDLIVTGPTRTNVNDYRVILIL

Sequences:

>Translated_432_residues
MKLDRAAARALLLESYAAAVAAADPLKIVAGFLPPPHAGGRTLVVGAGKAAASMALAVERAYAGRAQIEGLVVTRYAHGL
PTDHIRVIEAGHPVPDEAGEQAAQAIFDRVSALTEHDRLIVLVSGGGSSLLSLPAEGVPMADLKAVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPVTTLIVSDVAGDDPSAIASGPTVPDPSTYADALAILARWGAQAPESVRAHLERGARGE
IAETPKPGDACFARVANHVIATAQQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYGALARQVRRHGTPFAAPVALV
SGGECTVTLPPGLTGGRGGRCAEFLLSLGIALEDMGDVYALAADTDGIDGSEGNAGAVLDPQSIGRAAARGVAARAALDA
HDAYGFFAAAGDLIVTGPTRTNVNDYRVILIL
>Mature_432_residues
MKLDRAAARALLLESYAAAVAAADPLKIVAGFLPPPHAGGRTLVVGAGKAAASMALAVERAYAGRAQIEGLVVTRYAHGL
PTDHIRVIEAGHPVPDEAGEQAAQAIFDRVSALTEHDRLIVLVSGGGSSLLSLPAEGVPMADLKAVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPVTTLIVSDVAGDDPSAIASGPTVPDPSTYADALAILARWGAQAPESVRAHLERGARGE
IAETPKPGDACFARVANHVIATAQQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYGALARQVRRHGTPFAAPVALV
SGGECTVTLPPGLTGGRGGRCAEFLLSLGIALEDMGDVYALAADTDGIDGSEGNAGAVLDPQSIGRAAARGVAARAALDA
HDAYGFFAAAGDLIVTGPTRTNVNDYRVILIL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=450, Percent_Identity=33.1111111111111, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI193205461, Length=360, Percent_Identity=28.0555555555556, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI19920578, Length=438, Percent_Identity=29.6803652968037, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44083; Mature: 44083

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDRAAARALLLESYAAAVAAADPLKIVAGFLPPPHAGGRTLVVGAGKAAASMALAVER
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHH
AYAGRAQIEGLVVTRYAHGLPTDHIRVIEAGHPVPDEAGEQAAQAIFDRVSALTEHDRLI
HHCCHHHHCEEEEEEHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VLVSGGGSSLLSLPAEGVPMADLKAVTRELLRCGAPITDMNIVRKHLSRIQGGRLAAASR
EEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCC
APVTTLIVSDVAGDDPSAIASGPTVPDPSTYADALAILARWGAQAPESVRAHLERGARGE
CCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
IAETPKPGDACFARVANHVIATAQQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
ALARQVRRHGTPFAAPVALVSGGECTVTLPPGLTGGRGGRCAEFLLSLGIALEDMGDVYA
HHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHCCCCEEE
LAADTDGIDGSEGNAGAVLDPQSIGRAAARGVAARAALDAHDAYGFFAAAGDLIVTGPTR
EEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCC
TNVNDYRVILIL
CCCCCEEEEEEC
>Mature Secondary Structure
MKLDRAAARALLLESYAAAVAAADPLKIVAGFLPPPHAGGRTLVVGAGKAAASMALAVER
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHH
AYAGRAQIEGLVVTRYAHGLPTDHIRVIEAGHPVPDEAGEQAAQAIFDRVSALTEHDRLI
HHCCHHHHCEEEEEEHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VLVSGGGSSLLSLPAEGVPMADLKAVTRELLRCGAPITDMNIVRKHLSRIQGGRLAAASR
EEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCC
APVTTLIVSDVAGDDPSAIASGPTVPDPSTYADALAILARWGAQAPESVRAHLERGARGE
CCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
IAETPKPGDACFARVANHVIATAQQSLVAGAQVFAAHGIHTAILGDTVTGEAREVAQVYG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
ALARQVRRHGTPFAAPVALVSGGECTVTLPPGLTGGRGGRCAEFLLSLGIALEDMGDVYA
HHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCCCCCCHHHHHHHHHCCHHHCCCCEEE
LAADTDGIDGSEGNAGAVLDPQSIGRAAARGVAARAALDAHDAYGFFAAAGDLIVTGPTR
EEECCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCC
TNVNDYRVILIL
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]