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The map label for this gene is qseD [H]

Identifier: 17545198

GI number: 17545198

Start: 514495

End: 515439

Strand: Direct

Name: qseD [H]

Synonym: RSc0479

Alternate gene names: 17545198

Gene position: 514495-515439 (Clockwise)

Preceding gene: 17545197

Following gene: 17545199

Centisome position: 13.84

GC content: 67.09

Gene sequence:

>945_bases
ATGGAACTCAAATGGCTGGAAGATTTCATCAGCCTGGCGGAAACGCGCAGCTTTTCGCGTTCGGCCGAGCTGCGGCACGT
CACGCAGCCGGCCTTCTCGCGGCGCATCCAGTCGCTCGAAGCCTGGCTGGGCAATGAGCTGATCGACCGCTCCAGCTATC
CCACGCGCCTGACGCCCGCCGGCGAAGTCTTCTACGAACAGGCGCTGGCGATGCTCGCGCAGGTCAGCGAGACGCGCGCC
CTGATGCGCGGGCAGCGTCCGGCCAGCGCCTCGACCATCGATTTTGCGGTGCCGCATACGTTGTCGCTGACCTTCTTTCC
GGGCTGGCTGGCCAAGGTCGAGGAGAAGATCGGCAAGCTGCAGTGCCGGCTGCGCGCGCTCAACGTGCATGACGCGGTGA
TGACGCTGGTGGACGGCGGCTGCGATCTGGTCATGGTTTACCACCACGCGCGCCAGATGATCCAGCTCGACCCGACGCGC
TACGACATGCTGGTGCTCGGCACCGAGCGGCTGTCGCCGTTCAGCAAGCCCGACGTGGGCGGCCGCCCGATCTACAAGCT
GACGCCCGCCGCGCGCAAGCCGATCGCCTATCTTAGCTATACGCCCAATGCCTTCCTCGGGCGCATGGTCGATGTGCTGC
TGGAGAACTCGCCGGTGGCGCCGCTGCTCGACAAGTGCTACGAGACCGACATGGCCGAGGCGCTCAAGGTGATGGCGCTG
GCCGGGCATGGCGTCGCCTTTCTGCCCGAGAGCGCGGTACGCGACGATGTGGCGGCCGGACGGCTGGTCCGCGCCGAAGG
CAAGGGCGGCGGCACCCTGTCGATTGAGATGGAGATCCGGCTGTATCGCGAGCACCCGCAGAGCGGCGCGCACGACCGGC
GGCACCAGCAGTCCAAGCGCAAGCGCGAGCTGGTCGACATGCTGTGGGCCGTGCTGTCGGCGTGA

Upstream 100 bases:

>100_bases
AAAATGCCCTCCCAGCAGGCGCCCGTGTGGGGAGAGCGTCCGCCAGTCGAGCGGATGGCCACGGGCGCCGTCAGCACTGC
GGGGAAGGGGACACAAGTCG

Downstream 100 bases:

>100_bases
GGGCCGGAATGGGATCCATGCCGGGTTATGCGTGGCTGGCATAACCCGATGTAAAAACAGCATTGGATTTCGTTCAGGGG
CCTGCCTAAGCTGGCGGGCA

Product: transcription regulator protein

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAKVEEKIGKLQCRLRALNVHDAVMTLVDGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDVGGRPIYKLTPAARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVRDDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHQQSKRKRELVDMLWAVLSA

Sequences:

>Translated_314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAKVEEKIGKLQCRLRALNVHDAVMTLVDGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDVGGRPIYKLTPAARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVRDDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHQQSKRKRELVDMLWAVLSA
>Mature_314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAKVEEKIGKLQCRLRALNVHDAVMTLVDGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDVGGRPIYKLTPAARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVRDDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHQQSKRKRELVDMLWAVLSA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=264, Percent_Identity=31.8181818181818, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693105, Length=176, Percent_Identity=25, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=24.5421245421245, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790399, Length=146, Percent_Identity=28.0821917808219, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35147; Mature: 35147

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GEVFYEQALAMLAQVSETRALMRGQRPASASTIDFAVPHTLSLTFFPGWLAKVEEKIGKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHH
QCRLRALNVHDAVMTLVDGGCDLVMVYHHARQMIQLDPTRYDMLVLGTERLSPFSKPDVG
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCCCCC
GRPIYKLTPAARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
CCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPESAVRDDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHQQSKR
HCCCEEECCCHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHH
KRELVDMLWAVLSA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GEVFYEQALAMLAQVSETRALMRGQRPASASTIDFAVPHTLSLTFFPGWLAKVEEKIGKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHH
QCRLRALNVHDAVMTLVDGGCDLVMVYHHARQMIQLDPTRYDMLVLGTERLSPFSKPDVG
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCCCCC
GRPIYKLTPAARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
CCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPESAVRDDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHQQSKR
HCCCEEECCCHHHHHHHHCCCEEEECCCCCCEEEEEEEEEEEECCCCCCCHHHHHHHHHH
KRELVDMLWAVLSA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]