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The map label for this gene is gntK [H]

Identifier: 17545160

GI number: 17545160

Start: 468211

End: 468720

Strand: Reverse

Name: gntK [H]

Synonym: RSc0441

Alternate gene names: 17545160

Gene position: 468720-468211 (Counterclockwise)

Preceding gene: 17545166

Following gene: 17545157

Centisome position: 12.61

GC content: 68.63

Gene sequence:

>510_bases
ATGATCGTTGTGGTGATGGGTGTGTCGGGGTGCGGCAAGTCGACGGTGGGCCGCATGATTGCCGAGCGGCTGGGGTGCGC
CTTCCGCGACGGCGACGAATTCCACAGCGAGGCCAATCGCGCCAAGATGCACGCCGGCATCCCGCTCAACGACGACGACC
GCAAGCCCTGGCTCGAAACCATCCGCGCCTACATGGACGAGACCACGGCCGGCGGCCGCTCGCTGGTGGTGGCGTGCTCG
GCGCTCAAGGAACGGTACCGCGACGTGCTGCGCGGCCCGTCAGGCAGCACGGCGTTCGTCTACCTGAAAGGGGACTTCGA
GCTGCTGCAGAACCGCCTGGCCGCCCGCCAGGATCACTTCTTCAACCCGGTGCTGCTGCGCAGCCAGTTCGACGCGCTGG
AAGAGCCCGCCGACGCCATCGTGGTGGACATTGCGCTGCCGCAGGAGACCGTCGCGCAGCAGGCCGTCGAACAGCTGCAG
GCGCGCATGGCGCATCGCCCGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGACGAGGCCTGCGCATTGCTGCATCGCAGCAGAAAAAATCCGGGCCGGCCACCGCCGACGCGCTACCATGCCCGCCTGA
CGTTTCGGATGGGATTGGCG

Downstream 100 bases:

>100_bases
CGCGCACGCGCCGCTGCCACGGCGCATCAACTGCGTCAGCTACGCGAGAGCTGCTGCAGCACGGCCTGCACGTCCCCGTT
GCACACCCGGCTCATGCGGT

Product: thermoresistant gluconokinase (gluconate kinase 2) protein

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MIVVVMGVSGCGKSTVGRMIAERLGCAFRDGDEFHSEANRAKMHAGIPLNDDDRKPWLETIRAYMDETTAGGRSLVVACS
ALKERYRDVLRGPSGSTAFVYLKGDFELLQNRLAARQDHFFNPVLLRSQFDALEEPADAIVVDIALPQETVAQQAVEQLQ
ARMAHRPAA

Sequences:

>Translated_169_residues
MIVVVMGVSGCGKSTVGRMIAERLGCAFRDGDEFHSEANRAKMHAGIPLNDDDRKPWLETIRAYMDETTAGGRSLVVACS
ALKERYRDVLRGPSGSTAFVYLKGDFELLQNRLAARQDHFFNPVLLRSQFDALEEPADAIVVDIALPQETVAQQAVEQLQ
ARMAHRPAA
>Mature_169_residues
MIVVVMGVSGCGKSTVGRMIAERLGCAFRDGDEFHSEANRAKMHAGIPLNDDDRKPWLETIRAYMDETTAGGRSLVVACS
ALKERYRDVLRGPSGSTAFVYLKGDFELLQNRLAARQDHFFNPVLLRSQFDALEEPADAIVVDIALPQETVAQQAVEQLQ
ARMAHRPAA

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=153, Percent_Identity=45.0980392156863, Blast_Score=134, Evalue=5e-32,
Organism=Escherichia coli, GI87082265, Length=163, Percent_Identity=44.7852760736196, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790719, Length=170, Percent_Identity=38.2352941176471, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25146487, Length=158, Percent_Identity=44.9367088607595, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320454, Length=144, Percent_Identity=37.5, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18631; Mature: 18631

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVVMGVSGCGKSTVGRMIAERLGCAFRDGDEFHSEANRAKMHAGIPLNDDDRKPWLET
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
IRAYMDETTAGGRSLVVACSALKERYRDVLRGPSGSTAFVYLKGDFELLQNRLAARQDHF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
FNPVLLRSQFDALEEPADAIVVDIALPQETVAQQAVEQLQARMAHRPAA
CCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIVVVMGVSGCGKSTVGRMIAERLGCAFRDGDEFHSEANRAKMHAGIPLNDDDRKPWLET
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
IRAYMDETTAGGRSLVVACSALKERYRDVLRGPSGSTAFVYLKGDFELLQNRLAARQDHF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHCC
FNPVLLRSQFDALEEPADAIVVDIALPQETVAQQAVEQLQARMAHRPAA
CCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]