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The map label for this gene is pqqL [C]

Identifier: 17230236

GI number: 17230236

Start: 3342644

End: 3343927

Strand: Direct

Name: pqqL [C]

Synonym: alr2744

Alternate gene names: 17230236

Gene position: 3342644-3343927 (Clockwise)

Preceding gene: 17230235

Following gene: 17230237

Centisome position: 52.12

GC content: 43.93

Gene sequence:

>1284_bases
ATGACCCAAACCGTGAAACCATCCCTCGCTCAATCTCCCATTCATCGCACTGTACTAGACAATGGCATTGTCGTGCTGGT
AGCAGAAAATCCAGCCGCAGATATTATTGCTGGGCGAATTTTTATCCGTGCTGGTAGCTGCTACGAAAAGCGAGAACAGG
CGGGGTTAGCCCATTTGCTGGCTGCTGTAATGACTAAGGGATGTGAAGGACTTTCCAGTTTGGAAATAGCCGAACAAGTA
GAATCTGTGGGCGCAAGTTTGAGTGCAGATACTTCTACTGATTACTTTCTCGTGTCATTGAAGACGGTAACATCGGATTT
TCCCGAAATTTTAGCATTGGCGGGGCGGATATTGCGATCGCCTACATTCCCCGAAACTCAAATTGAACTGGAACGGCGTT
TAGCACTCCAAGATATTCGCTCCCAAAAAGAACAGCCTTTCACTCTTGCCTTTGAGCAAATGCGGCAGGTAATGTATCAA
AATCATCCCTACGCCATGTCAGTGCTAGGAGATGAAACCACCCTGAACAGCATCACCAGAACAGATTTAGTCGAGTATCA
CCAAACTTATTTCCGTCCAGATAACTTAGTCATCAGTGTTGCTGGTCGCATCACTCTACAAGAAGTAGTAGCCTTAGTAG
AACAAATATTCGGTGATTGGCAAGCACCAACCATAGCCCCAGCAGTAGTTAACTTACCAGAAATCTCAGTCAACCCCCAG
CACCGCTTAAAGCCTGTACAAACCCAGCAATCTATCGTCATGTTGGGTTATTTAGGCCCATCAGTCAGTTCTCCTGATTA
TGCCCCCCTCAAATTACTTTCTACTTACTTAGGCAATGGTCTTTCTAGCCGCTTGTTCGTAGAATTGCGAGAAAAGCGGG
GGTTAGCCTATGAAGTATCAGCATTCTACCCAACTAGGCTTTATCCAGCATCATTTGTAGTGTACATGGGTACAGCACCA
GAAAATACCAGCATCGCTTTAGAAGGATTACGGACAGAAGTAGAGCTACTCTGTAGTGAAGAAGTATCTACAACCAATTT
ACAAGCTGCTAAAAACAAAATATTGGGACAATATGCCTTAGGTAAACAAACTAATGGACAAATTGCTCAAATCTACGGTT
GGTATGAAATTTTGGGTTTAGGAATTGACTTTGACGGAGAATTTCAAGAACTGATTGCTTCTGTAACTGCTCAAGACGCT
TTAACATCGGCACAGCAGTATTTGCAGCAACCCTATGTGTCTTTAGTTGGGCAGGAAGAGGCAATTAATCGAGCAATTAA
TTAA

Upstream 100 bases:

>100_bases
TAAACCTTATTCATAATGTCAGTCGTCAGTGGCTAGTAGTCCGAGGCTGCAAAGAAGTCGACAACTGAACAACTGACAAC
TGATAATTGACAACTGACAA

Downstream 100 bases:

>100_bases
GTAGATGCTAAAAGAGTAGGACTTACGCAAACAGGTTATCTGTTGAGACCGGGTGTAAGGGTTTCCAGCATTTATACCCC
TACACCCTTGTCCAAACCCT

Product: processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTQTVKPSLAQSPIHRTVLDNGIVVLVAENPAADIIAGRIFIRAGSCYEKREQAGLAHLLAAVMTKGCEGLSSLEIAEQV
ESVGASLSADTSTDYFLVSLKTVTSDFPEILALAGRILRSPTFPETQIELERRLALQDIRSQKEQPFTLAFEQMRQVMYQ
NHPYAMSVLGDETTLNSITRTDLVEYHQTYFRPDNLVISVAGRITLQEVVALVEQIFGDWQAPTIAPAVVNLPEISVNPQ
HRLKPVQTQQSIVMLGYLGPSVSSPDYAPLKLLSTYLGNGLSSRLFVELREKRGLAYEVSAFYPTRLYPASFVVYMGTAP
ENTSIALEGLRTEVELLCSEEVSTTNLQAAKNKILGQYALGKQTNGQIAQIYGWYEILGLGIDFDGEFQELIASVTAQDA
LTSAQQYLQQPYVSLVGQEEAINRAIN

Sequences:

>Translated_427_residues
MTQTVKPSLAQSPIHRTVLDNGIVVLVAENPAADIIAGRIFIRAGSCYEKREQAGLAHLLAAVMTKGCEGLSSLEIAEQV
ESVGASLSADTSTDYFLVSLKTVTSDFPEILALAGRILRSPTFPETQIELERRLALQDIRSQKEQPFTLAFEQMRQVMYQ
NHPYAMSVLGDETTLNSITRTDLVEYHQTYFRPDNLVISVAGRITLQEVVALVEQIFGDWQAPTIAPAVVNLPEISVNPQ
HRLKPVQTQQSIVMLGYLGPSVSSPDYAPLKLLSTYLGNGLSSRLFVELREKRGLAYEVSAFYPTRLYPASFVVYMGTAP
ENTSIALEGLRTEVELLCSEEVSTTNLQAAKNKILGQYALGKQTNGQIAQIYGWYEILGLGIDFDGEFQELIASVTAQDA
LTSAQQYLQQPYVSLVGQEEAINRAIN
>Mature_426_residues
TQTVKPSLAQSPIHRTVLDNGIVVLVAENPAADIIAGRIFIRAGSCYEKREQAGLAHLLAAVMTKGCEGLSSLEIAEQVE
SVGASLSADTSTDYFLVSLKTVTSDFPEILALAGRILRSPTFPETQIELERRLALQDIRSQKEQPFTLAFEQMRQVMYQN
HPYAMSVLGDETTLNSITRTDLVEYHQTYFRPDNLVISVAGRITLQEVVALVEQIFGDWQAPTIAPAVVNLPEISVNPQH
RLKPVQTQQSIVMLGYLGPSVSSPDYAPLKLLSTYLGNGLSSRLFVELREKRGLAYEVSAFYPTRLYPASFVVYMGTAPE
NTSIALEGLRTEVELLCSEEVSTTNLQAAKNKILGQYALGKQTNGQIAQIYGWYEILGLGIDFDGEFQELIASVTAQDAL
TSAQQYLQQPYVSLVGQEEAINRAIN

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=351, Percent_Identity=24.7863247863248, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI46593007, Length=270, Percent_Identity=24.8148148148148, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI24308013, Length=436, Percent_Identity=19.954128440367, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553678, Length=217, Percent_Identity=26.7281105990783, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71999683, Length=203, Percent_Identity=26.1083743842365, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323192, Length=210, Percent_Identity=27.1428571428571, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321813, Length=339, Percent_Identity=22.1238938053097, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21357875, Length=262, Percent_Identity=26.3358778625954, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646943, Length=262, Percent_Identity=26.3358778625954, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46999; Mature: 46868

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTVKPSLAQSPIHRTVLDNGIVVLVAENPAADIIAGRIFIRAGSCYEKREQAGLAHLL
CCCCCCCHHHHCCHHHHHHCCCEEEEEECCCCHHHHEEEEEEECCCHHHHHHHHHHHHHH
AAVMTKGCEGLSSLEIAEQVESVGASLSADTSTDYFLVSLKTVTSDFPEILALAGRILRS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHCC
PTFPETQIELERRLALQDIRSQKEQPFTLAFEQMRQVMYQNHPYAMSVLGDETTLNSITR
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
TDLVEYHQTYFRPDNLVISVAGRITLQEVVALVEQIFGDWQAPTIAPAVVNLPEISVNPQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHH
HRLKPVQTQQSIVMLGYLGPSVSSPDYAPLKLLSTYLGNGLSSRLFVELREKRGLAYEVS
HCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
AFYPTRLYPASFVVYMGTAPENTSIALEGLRTEVELLCSEEVSTTNLQAAKNKILGQYAL
ECCCCEECCCEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GKQTNGQIAQIYGWYEILGLGIDFDGEFQELIASVTAQDALTSAQQYLQQPYVSLVGQEE
CCCCCCCEEEHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHH
AINRAIN
HHHHCCC
>Mature Secondary Structure 
TQTVKPSLAQSPIHRTVLDNGIVVLVAENPAADIIAGRIFIRAGSCYEKREQAGLAHLL
CCCCCCHHHHCCHHHHHHCCCEEEEEECCCCHHHHEEEEEEECCCHHHHHHHHHHHHHH
AAVMTKGCEGLSSLEIAEQVESVGASLSADTSTDYFLVSLKTVTSDFPEILALAGRILRS
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHCC
PTFPETQIELERRLALQDIRSQKEQPFTLAFEQMRQVMYQNHPYAMSVLGDETTLNSITR
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHH
TDLVEYHQTYFRPDNLVISVAGRITLQEVVALVEQIFGDWQAPTIAPAVVNLPEISVNPQ
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCHH
HRLKPVQTQQSIVMLGYLGPSVSSPDYAPLKLLSTYLGNGLSSRLFVELREKRGLAYEVS
HCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEE
AFYPTRLYPASFVVYMGTAPENTSIALEGLRTEVELLCSEEVSTTNLQAAKNKILGQYAL
ECCCCEECCCEEEEEECCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GKQTNGQIAQIYGWYEILGLGIDFDGEFQELIASVTAQDALTSAQQYLQQPYVSLVGQEE
CCCCCCCEEEHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHH
AINRAIN
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]