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The map label for this gene is coxC [H]

Identifier: 17230226

GI number: 17230226

Start: 3331632

End: 3332234

Strand: Direct

Name: coxC [H]

Synonym: alr2734

Alternate gene names: 17230226

Gene position: 3331632-3332234 (Clockwise)

Preceding gene: 17230224

Following gene: 17230227

Centisome position: 51.94

GC content: 39.97

Gene sequence:

>603_bases
ATGGATAGTTCTTTATCTCATAATGAAGGTCATGAAATCAGCCATGAACATGGACATGATGAAGAAGGCAATAAAATGTT
CGGCTTTATTGTCTTTTTACTATCTGAAAGCGTCATTTTCTTGAGCTTTTTCGCCGGATATATTGTCTACAAAACAACTA
CTCCTAACTGGCTACCAGTTGGTGTGGAGGGGTTAGAAGTTAGAGACCCAGCCATCAATACAGTAGTATTGGTTGCTAGT
AGCTTTGTGATTTATTTTGCAGAACTCGCCCTAAAACGCCAAAATTTGCGGTTATTCCGCATCTTTTTGTCAGCAACAAT
GGCAATGGGTAGCTACTTTTTGGTAGGACAAGCCATTGAATGGAGTCATTTAGAGTTTGGCTTTACTTCTGGCGTATATG
GTGGAATGTTCTATCTGTTAACAGGGTTCCACGGTTTGCACGTTTTTACAGGTATCTTGTTACAGTTTATTATTCTTGTG
CGATCGCTCATTCCTGGTAACTACGATACAGGTCACTTCGGCGTAAACGCAACTTCTTTGTTTTGGCACTTCGTCGATGT
CATCTGGATTATTTTGTTTATCCTTATCTACATCTGGCAGTAG

Upstream 100 bases:

>100_bases
TCATTCAATGAATTTTGATTTGTTATATCTCAGATTCAATGAAATTGCCTAGCTTTTCTCAAGTCTTTACACCCTTACAC
CCATATAACCCTACACCCCT

Downstream 100 bases:

>100_bases
CACCAAACTCAATCCCTACCAGTACTTACAAAAAGTAACCAATTCAGCAGAGCCAACCCATACACTGGCTCTGCTTTATG
CCTGTAAAATCACATTAGCC

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MDSSLSHNEGHEISHEHGHDEEGNKMFGFIVFLLSESVIFLSFFAGYIVYKTTTPNWLPVGVEGLEVRDPAINTVVLVAS
SFVIYFAELALKRQNLRLFRIFLSATMAMGSYFLVGQAIEWSHLEFGFTSGVYGGMFYLLTGFHGLHVFTGILLQFIILV
RSLIPGNYDTGHFGVNATSLFWHFVDVIWIILFILIYIWQ

Sequences:

>Translated_200_residues
MDSSLSHNEGHEISHEHGHDEEGNKMFGFIVFLLSESVIFLSFFAGYIVYKTTTPNWLPVGVEGLEVRDPAINTVVLVAS
SFVIYFAELALKRQNLRLFRIFLSATMAMGSYFLVGQAIEWSHLEFGFTSGVYGGMFYLLTGFHGLHVFTGILLQFIILV
RSLIPGNYDTGHFGVNATSLFWHFVDVIWIILFILIYIWQ
>Mature_200_residues
MDSSLSHNEGHEISHEHGHDEEGNKMFGFIVFLLSESVIFLSFFAGYIVYKTTTPNWLPVGVEGLEVRDPAINTVVLVAS
SFVIYFAELALKRQNLRLFRIFLSATMAMGSYFLVGQAIEWSHLEFGFTSGVYGGMFYLLTGFHGLHVFTGILLQFIILV
RSLIPGNYDTGHFGVNATSLFWHFVDVIWIILFILIYIWQ

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=190, Percent_Identity=34.7368421052632, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1786633, Length=200, Percent_Identity=32, Blast_Score=94, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6226542, Length=183, Percent_Identity=31.1475409836066, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 22713; Mature: 22713

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSLSHNEGHEISHEHGHDEEGNKMFGFIVFLLSESVIFLSFFAGYIVYKTTTPNWLPV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEC
GVEGLEVRDPAINTVVLVASSFVIYFAELALKRQNLRLFRIFLSATMAMGSYFLVGQAIE
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCC
WSHLEFGFTSGVYGGMFYLLTGFHGLHVFTGILLQFIILVRSLIPGNYDTGHFGVNATSL
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FWHFVDVIWIILFILIYIWQ
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSSLSHNEGHEISHEHGHDEEGNKMFGFIVFLLSESVIFLSFFAGYIVYKTTTPNWLPV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEC
GVEGLEVRDPAINTVVLVASSFVIYFAELALKRQNLRLFRIFLSATMAMGSYFLVGQAIE
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCC
WSHLEFGFTSGVYGGMFYLLTGFHGLHVFTGILLQFIILVRSLIPGNYDTGHFGVNATSL
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
FWHFVDVIWIILFILIYIWQ
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]