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The map label for this gene is zraS [C]

Identifier: 17230064

GI number: 17230064

Start: 3073430

End: 3074932

Strand: Direct

Name: zraS [C]

Synonym: alr2572

Alternate gene names: 17230064

Gene position: 3073430-3074932 (Clockwise)

Preceding gene: 17230062

Following gene: 17230066

Centisome position: 47.92

GC content: 43.98

Gene sequence:

>1503_bases
GTGTACGAATGGATATTGCCAAGTCTGAGTGAAGTTTTAGCCGAAGGTCAGGGAACTGTGGCTGAATGCTCACCAACCAA
AGCAGAGCGACAGTGGCGCATGAGTCTAGCCGCGACAGAACATTTGCTCATTAACAGTTTAGTTGCTGTTGGATCTGAGG
CGCTTCAAGGATTAGTTTTAGCTGCACCTGCACCCCTCTTTAGTCAACCTATCCTCACTCAAAACTTACAGACGATTACT
TTTACAGCCAGGCCGTTTAACCCTTTGGCATTGATGCCATTTCAAATGCCAAGTGCGATCGCCTCTACAGAGTCAAAAAC
TGCCCTTTGTGAGCCTGTATTACCTTTACTACCTGCCGATCCTTTGGCATCTGAGCAATTTTGTTTAATATTTACAGATA
AATTTAGATTAGTTTTAGTTCTCGCCACACATAAAAACGGTAAAAAAGCTTTCTCGTTTTCCTTTGAGCCAGAGATAGTC
CAGCAGGCTTGGCGATCGCTAGGCGCGCGGGTAATGCTGACTAATCCTGATTTGTTCACGGAGTTGGATAGTTTAGTACA
ACAGTATCCAGCGATCGCACCTGATTACCTGACAGTACTCCAGTTTAGCCAATTTTTACTCCAAGAATTACCAGAGGAAG
AAACTAGAGATTGGGGATTAGGAAGAAGCCGGGGAGGAGAGGAGCAAGGTAACAGAGTAGAGGAAATTCCCTATCCTCAA
TGTCCCATACCTAATGTCCAATGTCCCATACCTAATCCTCCATCAATCAAACCTGATGTAGAATTATTGCAAGCTTTTGC
TCACGAAGTCCGTACACCGTTGACTACTATTCGTACTATGACTCGTCTGCTGCTGAAGCGGCGTGATTTACCAGCCAATG
TGATGAATCGTCTAGAAATTATCGATCATGAGTGTACTGAGCAAATTGATCGCATGGAGTTGCTATTTAAAGCAGCAGAA
CTAGAAACATCTACTTCCGGGAAATCTGCGAATCCTCATTTAACAGCAATGTCTTTGGATCAAGTGTTGCAACAAAGTAT
CCCTCGTTGGCAACAAGCAGCCGAACGGCGAAACTTGACCCTAGATGTAGTTTTACCCCAACAATTACCCACTGTGGTGA
GCAATCCTAATATGCTGGATCGTGTACTTACAGGGTTGATGGAGAATTTTACCCGCAGTTTACCAGCCGGGAGCCATATT
CAAGTACAAGTGATTCCGGCAGGAGATCAATTAAAGTTACAATTGTCTCCTCACACTCACTGCAAAGATAGCAATAAAGC
CAGCGCACCAGTTACACCACCCATCCGTAAAGCTTTGGGACAATTACTCATGTTCCAACCAGAAACAGGCACAATTAGTT
TAAATATCGCTGCTACCAAGCACTTATTTCAAGCGATCGGTGGTAAGTTAATCGTCCGCCAACGCCCACACTACGGCGAA
GTATTAACTATTTTCTTACCGCTAGAAGTCAGTAACAAGCAAAACTTAACTATAAAGAGGTAA

Upstream 100 bases:

>100_bases
GACTGTTATTAGGGCATAAATAACTATACGCTCATAGGTAGTAAAGAAATTTTGAATTTTCCGAGCTGCTAGTCGCTCTT
GAAAGAAGGGGTGAAGTTCT

Downstream 100 bases:

>100_bases
GCTTACCGCGCTATTTTTCACAATTAATTGTACAGACGCGATTAATCGCGTCTCTCTAACAATTACCGAGCGATTAATCG
CGTCTCTAACAATTACCGAG

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: Two-Component Sensor Histidine Kinase; Sensor Histidine Kinase; Signal Transduction Histidine Kinase; Histidine Kinase A Domain Protein; Two Component System Sensor Histidine Kinase; Sensory Transduction Histidine Kinase

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MYEWILPSLSEVLAEGQGTVAECSPTKAERQWRMSLAATEHLLINSLVAVGSEALQGLVLAAPAPLFSQPILTQNLQTIT
FTARPFNPLALMPFQMPSAIASTESKTALCEPVLPLLPADPLASEQFCLIFTDKFRLVLVLATHKNGKKAFSFSFEPEIV
QQAWRSLGARVMLTNPDLFTELDSLVQQYPAIAPDYLTVLQFSQFLLQELPEEETRDWGLGRSRGGEEQGNRVEEIPYPQ
CPIPNVQCPIPNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVMNRLEIIDHECTEQIDRMELLFKAAE
LETSTSGKSANPHLTAMSLDQVLQQSIPRWQQAAERRNLTLDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHI
QVQVIPAGDQLKLQLSPHTHCKDSNKASAPVTPPIRKALGQLLMFQPETGTISLNIAATKHLFQAIGGKLIVRQRPHYGE
VLTIFLPLEVSNKQNLTIKR

Sequences:

>Translated_500_residues
MYEWILPSLSEVLAEGQGTVAECSPTKAERQWRMSLAATEHLLINSLVAVGSEALQGLVLAAPAPLFSQPILTQNLQTIT
FTARPFNPLALMPFQMPSAIASTESKTALCEPVLPLLPADPLASEQFCLIFTDKFRLVLVLATHKNGKKAFSFSFEPEIV
QQAWRSLGARVMLTNPDLFTELDSLVQQYPAIAPDYLTVLQFSQFLLQELPEEETRDWGLGRSRGGEEQGNRVEEIPYPQ
CPIPNVQCPIPNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVMNRLEIIDHECTEQIDRMELLFKAAE
LETSTSGKSANPHLTAMSLDQVLQQSIPRWQQAAERRNLTLDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHI
QVQVIPAGDQLKLQLSPHTHCKDSNKASAPVTPPIRKALGQLLMFQPETGTISLNIAATKHLFQAIGGKLIVRQRPHYGE
VLTIFLPLEVSNKQNLTIKR
>Mature_500_residues
MYEWILPSLSEVLAEGQGTVAECSPTKAERQWRMSLAATEHLLINSLVAVGSEALQGLVLAAPAPLFSQPILTQNLQTIT
FTARPFNPLALMPFQMPSAIASTESKTALCEPVLPLLPADPLASEQFCLIFTDKFRLVLVLATHKNGKKAFSFSFEPEIV
QQAWRSLGARVMLTNPDLFTELDSLVQQYPAIAPDYLTVLQFSQFLLQELPEEETRDWGLGRSRGGEEQGNRVEEIPYPQ
CPIPNVQCPIPNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVMNRLEIIDHECTEQIDRMELLFKAAE
LETSTSGKSANPHLTAMSLDQVLQQSIPRWQQAAERRNLTLDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHI
QVQVIPAGDQLKLQLSPHTHCKDSNKASAPVTPPIRKALGQLLMFQPETGTISLNIAATKHLFQAIGGKLIVRQRPHYGE
VLTIFLPLEVSNKQNLTIKR

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. May Function As A Membrane-Associated Protein Kinase That Phosphorylates Zrar In Response To High Concentrations Of Zinc Or Lead In The Medium. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.3.- [C]

Molecular weight: Translated: 55631; Mature: 55631

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEWILPSLSEVLAEGQGTVAECSPTKAERQWRMSLAATEHLLINSLVAVGSEALQGLVL
CCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
AAPAPLFSQPILTQNLQTITFTARPFNPLALMPFQMPSAIASTESKTALCEPVLPLLPAD
ECCCCHHCCCHHHCCCEEEEEEECCCCCEEEECCCCCHHHHCCCCCHHHHCCCHHCCCCC
PLASEQFCLIFTDKFRLVLVLATHKNGKKAFSFSFEPEIVQQAWRSLGARVMLTNPDLFT
CCCCCCEEEEEECCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCHHHH
ELDSLVQQYPAIAPDYLTVLQFSQFLLQELPEEETRDWGLGRSRGGEEQGNRVEEIPYPQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
CPIPNVQCPIPNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVMNRLEI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IDHECTEQIDRMELLFKAAELETSTSGKSANPHLTAMSLDQVLQQSIPRWQQAAERRNLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCHHHHHHHHHCCCE
LDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHIQVQVIPAGDQLKLQLSPHTH
EEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCC
CKDSNKASAPVTPPIRKALGQLLMFQPETGTISLNIAATKHLFQAIGGKLIVRQRPHYGE
CCCCCCCCCCCCHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VLTIFLPLEVSNKQNLTIKR
EEEEEEEEEECCCCCCEEEC
>Mature Secondary Structure
MYEWILPSLSEVLAEGQGTVAECSPTKAERQWRMSLAATEHLLINSLVAVGSEALQGLVL
CCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
AAPAPLFSQPILTQNLQTITFTARPFNPLALMPFQMPSAIASTESKTALCEPVLPLLPAD
ECCCCHHCCCHHHCCCEEEEEEECCCCCEEEECCCCCHHHHCCCCCHHHHCCCHHCCCCC
PLASEQFCLIFTDKFRLVLVLATHKNGKKAFSFSFEPEIVQQAWRSLGARVMLTNPDLFT
CCCCCCEEEEEECCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCEEEEECCHHHH
ELDSLVQQYPAIAPDYLTVLQFSQFLLQELPEEETRDWGLGRSRGGEEQGNRVEEIPYPQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
CPIPNVQCPIPNPPSIKPDVELLQAFAHEVRTPLTTIRTMTRLLLKRRDLPANVMNRLEI
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IDHECTEQIDRMELLFKAAELETSTSGKSANPHLTAMSLDQVLQQSIPRWQQAAERRNLT
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHCHHHHHHHHHCCCE
LDVVLPQQLPTVVSNPNMLDRVLTGLMENFTRSLPAGSHIQVQVIPAGDQLKLQLSPHTH
EEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCC
CKDSNKASAPVTPPIRKALGQLLMFQPETGTISLNIAATKHLFQAIGGKLIVRQRPHYGE
CCCCCCCCCCCCHHHHHHHHHHEEECCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VLTIFLPLEVSNKQNLTIKR
EEEEEEEEEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA