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The map label for this gene is coxC [H]

Identifier: 17230008

GI number: 17230008

Start: 3024037

End: 3024630

Strand: Direct

Name: coxC [H]

Synonym: alr2516

Alternate gene names: 17230008

Gene position: 3024037-3024630 (Clockwise)

Preceding gene: 17230007

Following gene: 17230009

Centisome position: 47.15

GC content: 44.78

Gene sequence:

>594_bases
ATGACTAGTGTGACGGCGCATGAGGCTCATGGGGGACATGAGGCGCATCCAGATTTACGGGTTTGGGGGTTGTTGACTTT
CCTGATTTCTGAATCTTTGATGTTTGGCGGATTTTTTGCTACGTATCTGTTTTTTAAGGGGACTACCGAGGTGTGGCCGC
CGGAAGGAACAGAGGTAGAGTTGTTTGTTCCAGCAATTAACACCGCCATTCTCTTATCTAGTAGTGTGGTCATTCACTTC
GGTGATATGGCGATTAAGAAGGGTAATGTCTGGGGAATGCGGATTTGGTATTTCCTGACGGCGATTATGGGAGCAGTATT
TTTAGCTGGTCAGGTATATGAGTACCAGAATTTAGGGTACGGCCTGACTGCTAATGTGTTCGCCAACTGCTTCTATATCA
TGACCGGGTTCCACGGACTGCACGTATTTATTGGGCTGTTATTGATTTTAGGTGTGTTGTGGCGATCGCGCCGTTCTGGA
CATTATTCAGAAACTAAACATACTGGCATCGAAATGGCAGAAATTTACTGGCACTTTGTAGACATCATCTGGATTGTTCT
TTTTACCTTGGTTTATCTGCTCAATCTTTTGTAA

Upstream 100 bases:

>100_bases
GTTCTCCTCTCTGACCTTCGGCACGCTCCGCGAACGAAGAAAATTTAGGAGAGGGGTTAGGTGAGAGGTAAAGAGCCGAA
AAATTGATGGAGAAGTGAAT

Downstream 100 bases:

>100_bases
ATACAAGGGTAATGGGTAATTGGTAATTAATAATAGTTTGTTCAATTACCTATTACCCATTAGCTATTACCAATTCCCAG
GAGGTTATTTTGCACACAGA

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTSVTAHEAHGGHEAHPDLRVWGLLTFLISESLMFGGFFATYLFFKGTTEVWPPEGTEVELFVPAINTAILLSSSVVIHF
GDMAIKKGNVWGMRIWYFLTAIMGAVFLAGQVYEYQNLGYGLTANVFANCFYIMTGFHGLHVFIGLLLILGVLWRSRRSG
HYSETKHTGIEMAEIYWHFVDIIWIVLFTLVYLLNLL

Sequences:

>Translated_197_residues
MTSVTAHEAHGGHEAHPDLRVWGLLTFLISESLMFGGFFATYLFFKGTTEVWPPEGTEVELFVPAINTAILLSSSVVIHF
GDMAIKKGNVWGMRIWYFLTAIMGAVFLAGQVYEYQNLGYGLTANVFANCFYIMTGFHGLHVFIGLLLILGVLWRSRRSG
HYSETKHTGIEMAEIYWHFVDIIWIVLFTLVYLLNLL
>Mature_196_residues
TSVTAHEAHGGHEAHPDLRVWGLLTFLISESLMFGGFFATYLFFKGTTEVWPPEGTEVELFVPAINTAILLSSSVVIHFG
DMAIKKGNVWGMRIWYFLTAIMGAVFLAGQVYEYQNLGYGLTANVFANCFYIMTGFHGLHVFIGLLLILGVLWRSRRSGH
YSETKHTGIEMAEIYWHFVDIIWIVLFTLVYLLNLL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=143, Percent_Identity=33.5664335664336, Blast_Score=84, Evalue=7e-17,
Organism=Escherichia coli, GI1786633, Length=197, Percent_Identity=31.9796954314721, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6226542, Length=177, Percent_Identity=32.7683615819209, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 22303; Mature: 22172

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVTAHEAHGGHEAHPDLRVWGLLTFLISESLMFGGFFATYLFFKGTTEVWPPEGTEVE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LFVPAINTAILLSSSVVIHFGDMAIKKGNVWGMRIWYFLTAIMGAVFLAGQVYEYQNLGY
EEECCHHHHHHHHCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLTANVFANCFYIMTGFHGLHVFIGLLLILGVLWRSRRSGHYSETKHTGIEMAEIYWHFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHH
DIIWIVLFTLVYLLNLL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSVTAHEAHGGHEAHPDLRVWGLLTFLISESLMFGGFFATYLFFKGTTEVWPPEGTEVE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LFVPAINTAILLSSSVVIHFGDMAIKKGNVWGMRIWYFLTAIMGAVFLAGQVYEYQNLGY
EEECCHHHHHHHHCCEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLTANVFANCFYIMTGFHGLHVFIGLLLILGVLWRSRRSGHYSETKHTGIEMAEIYWHFV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHH
DIIWIVLFTLVYLLNLL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8399373 [H]