Click here to switch to the map view.

The map label for this gene is nadD [H]

Identifier: 17229975

GI number: 17229975

Start: 2983911

End: 2984513

Strand: Direct

Name: nadD [H]

Synonym: alr2483

Alternate gene names: 17229975

Gene position: 2983911-2984513 (Clockwise)

Preceding gene: 17229974

Following gene: 17229976

Centisome position: 46.52

GC content: 44.11

Gene sequence:

>603_bases
ATGAAAAAAATTGCTTTATTTGGTACTAGTGCAGACCCACCAACAGCAGGACATCAGATTATTTTACGCTGGTTGTCTGA
GCGTTATGATTGGGTGGCGGTTTGGGCGGCGGATAACCCGTTTAAATCTCATCAAACACTATTAGAGCATCGGGCGGCAA
TGCTGCGGCTGTTGATTGCGGATATAGAAGCGCCTCGGCAGAATATAGCTTTAGAACAGGATTTGAGTAGCTTTAGAACT
CTGGAAACATTGGAGAAGGCGAAATTACGTTGGGGTGCAAATACAGAGTTTACTTTGATCATTGGTTCAGATTTACTGAG
TCAGTTACCCCGTTGGTATCGAGTTGAAGAATTATTACAGCAGGTGCAACTGTTGATTGTGCCACGACCAGGATATGCCA
TAGATGGGACTAGTCTAGAAGCTGTGCAACAACTGGGCGGTAAAATTGCGATCGCCTCTTTTACAGGTCTAGATGTTTCC
TCAACAGCATATCGTGAACGTGGAGAAACTGAAGCTCTCACCCCCCCTATAGTCGAATACATTCATCAACAGCATTTGTA
CAAATGCCCGGACGCAACCAAAAAAAGTTTTCAACTTCGTTAA

Upstream 100 bases:

>100_bases
ACGTTTAGATAATCCCGTTCCCGTACCCATACAAATTTCCACCGCATTGCAAGATTTGACAGAAGTTACATTGCAACGTC
TCAACTAACGACAACTGACA

Downstream 100 bases:

>100_bases
ATCAACAACCTTTAGCCGATTTTAAGGTTGGTGTTGATAATGTAATTTTTTCTGTAGATACTGAAAAAAATCGGCTGTTA
GTTCTGTTAGTAATGCGACA

Product: nicotinic acid mononucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKKIALFGTSADPPTAGHQIILRWLSERYDWVAVWAADNPFKSHQTLLEHRAAMLRLLIADIEAPRQNIALEQDLSSFRT
LETLEKAKLRWGANTEFTLIIGSDLLSQLPRWYRVEELLQQVQLLIVPRPGYAIDGTSLEAVQQLGGKIAIASFTGLDVS
STAYRERGETEALTPPIVEYIHQQHLYKCPDATKKSFQLR

Sequences:

>Translated_200_residues
MKKIALFGTSADPPTAGHQIILRWLSERYDWVAVWAADNPFKSHQTLLEHRAAMLRLLIADIEAPRQNIALEQDLSSFRT
LETLEKAKLRWGANTEFTLIIGSDLLSQLPRWYRVEELLQQVQLLIVPRPGYAIDGTSLEAVQQLGGKIAIASFTGLDVS
STAYRERGETEALTPPIVEYIHQQHLYKCPDATKKSFQLR
>Mature_200_residues
MKKIALFGTSADPPTAGHQIILRWLSERYDWVAVWAADNPFKSHQTLLEHRAAMLRLLIADIEAPRQNIALEQDLSSFRT
LETLEKAKLRWGANTEFTLIIGSDLLSQLPRWYRVEELLQQVQLLIVPRPGYAIDGTSLEAVQQLGGKIAIASFTGLDVS
STAYRERGETEALTPPIVEYIHQQHLYKCPDATKKSFQLR

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) [H]

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family [H]

Homologues:

Organism=Escherichia coli, GI1786858, Length=216, Percent_Identity=31.0185185185185, Blast_Score=70, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.18 [H]

Molecular weight: Translated: 22653; Mature: 22653

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIALFGTSADPPTAGHQIILRWLSERYDWVAVWAADNPFKSHQTLLEHRAAMLRLLIA
CCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
DIEAPRQNIALEQDLSSFRTLETLEKAKLRWGANTEFTLIIGSDLLSQLPRWYRVEELLQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHCHHHHHHHHHHH
QVQLLIVPRPGYAIDGTSLEAVQQLGGKIAIASFTGLDVSSTAYRERGETEALTPPIVEY
HHHEEEECCCCCEECCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCCHHHHHH
IHQQHLYKCPDATKKSFQLR
HHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKKIALFGTSADPPTAGHQIILRWLSERYDWVAVWAADNPFKSHQTLLEHRAAMLRLLIA
CCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
DIEAPRQNIALEQDLSSFRTLETLEKAKLRWGANTEFTLIIGSDLLSQLPRWYRVEELLQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHCHHHHHHHHHHH
QVQLLIVPRPGYAIDGTSLEAVQQLGGKIAIASFTGLDVSSTAYRERGETEALTPPIVEY
HHHEEEECCCCCEECCCCHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCCHHHHHH
IHQQHLYKCPDATKKSFQLR
HHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]