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The map label for this gene is purQ [H]

Identifier: 17229967

GI number: 17229967

Start: 2971782

End: 2972456

Strand: Direct

Name: purQ [H]

Synonym: alr2475

Alternate gene names: 17229967

Gene position: 2971782-2972456 (Clockwise)

Preceding gene: 17229966

Following gene: 17229968

Centisome position: 46.33

GC content: 47.26

Gene sequence:

>675_bases
ATGAAATTTGGCGTTGTTGTATTTCCTGGTTCTAATTGCGATCGCGATGTTGCCTATGTCACTAGAGACTTGCTAGGACA
GCCAACTCGCATGGTTTGGCATCAAGACACCGATATTGCTGATTTGGATGTGGTGATTATCCCTGGTGGATTTAGTTATG
GTGACTATTTACGCTGTGGGGCGATCGCTCGGTTCTCTCCTGTGATGCAGCAGGTGGTGGAACACGCCCAAAAAGGTAAG
TTGGTGCTGGGGATTTGTAACGGTTTTCAGGTATTAACTGAAGCCGGACTCTTACCTGGAGCCTTGGCGAGAAATCAAGA
TTTGCATTTTATTTGCGATCGCGTCCCTCTCACTGTTGAGAGTACCAATAGCCTTTGGACTCAAGCTTACAACCCTGGTG
AAGTCATCACTCTCCCAATTGCCCACGGAGAAGGCAGATTTTATGCTGATGAGGCAACTTTATCTGAGATTGAAGATAAT
GGGCAGGTGCTTTTCCGTTATGCGGGTGAAAATCCCAATGGTTCCCTGAATAATATAGCCGGGATTTGCGATCGCCAAGG
CAATGTTTTAGGCATGATGCCTCACCCAGAAAGGGCTTCTGACCCTGTGCTTGGTGGTAGCGATGGATTAAAGTTATTCC
AAGGGTTGCTTGAGAAGGTGGTGGCGTTGGCATAA

Upstream 100 bases:

>100_bases
ACGCTCGTTCCTCGCTAACGCTGCGCTAACGCCAGTTACTCATGGGGGAAACCCCCAAGACCGTACTGGCTCACAACTAA
CAACTAACAACTGACTAATC

Downstream 100 bases:

>100_bases
TGTTGACCTTCGCACCCATCATAGTTAAACAAGATAGAGGCACAGTCAGGCTGTGCCTTTCTCAGTTTCTATTAAAGTGC
TTATTGTAACTATATAATGT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVWHQDTDIADLDVVIIPGGFSYGDYLRCGAIARFSPVMQQVVEHAQKGK
LVLGICNGFQVLTEAGLLPGALARNQDLHFICDRVPLTVESTNSLWTQAYNPGEVITLPIAHGEGRFYADEATLSEIEDN
GQVLFRYAGENPNGSLNNIAGICDRQGNVLGMMPHPERASDPVLGGSDGLKLFQGLLEKVVALA

Sequences:

>Translated_224_residues
MKFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVWHQDTDIADLDVVIIPGGFSYGDYLRCGAIARFSPVMQQVVEHAQKGK
LVLGICNGFQVLTEAGLLPGALARNQDLHFICDRVPLTVESTNSLWTQAYNPGEVITLPIAHGEGRFYADEATLSEIEDN
GQVLFRYAGENPNGSLNNIAGICDRQGNVLGMMPHPERASDPVLGGSDGLKLFQGLLEKVVALA
>Mature_224_residues
MKFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVWHQDTDIADLDVVIIPGGFSYGDYLRCGAIARFSPVMQQVVEHAQKGK
LVLGICNGFQVLTEAGLLPGALARNQDLHFICDRVPLTVESTNSLWTQAYNPGEVITLPIAHGEGRFYADEATLSEIEDN
GQVLFRYAGENPNGSLNNIAGICDRQGNVLGMMPHPERASDPVLGGSDGLKLFQGLLEKVVALA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=185, Percent_Identity=32.4324324324324, Blast_Score=74, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17553022, Length=241, Percent_Identity=25.7261410788382, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321498, Length=181, Percent_Identity=32.5966850828729, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24582111, Length=185, Percent_Identity=33.5135135135135, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582109, Length=185, Percent_Identity=33.5135135135135, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17137292, Length=185, Percent_Identity=33.5135135135135, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24258; Mature: 24258

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVWHQDTDIADLDVVIIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHC
AIARFSPVMQQVVEHAQKGKLVLGICNGFQVLTEAGLLPGALARNQDLHFICDRVPLTVE
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCCEEEECCCCEEEE
STNSLWTQAYNPGEVITLPIAHGEGRFYADEATLSEIEDNGQVLFRYAGENPNGSLNNIA
CCCCCEEECCCCCCEEEEEEECCCCCEEECCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
GICDRQGNVLGMMPHPERASDPVLGGSDGLKLFQGLLEKVVALA
HHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFGVVVFPGSNCDRDVAYVTRDLLGQPTRMVWHQDTDIADLDVVIIPGGFSYGDYLRCG
CCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCHHHHC
AIARFSPVMQQVVEHAQKGKLVLGICNGFQVLTEAGLLPGALARNQDLHFICDRVPLTVE
HHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCCEEEECCCCEEEE
STNSLWTQAYNPGEVITLPIAHGEGRFYADEATLSEIEDNGQVLFRYAGENPNGSLNNIA
CCCCCEEECCCCCCEEEEEEECCCCCEEECCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
GICDRQGNVLGMMPHPERASDPVLGGSDGLKLFQGLLEKVVALA
HHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA