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The map label for this gene is uvsE

Identifier: 17228758

GI number: 17228758

Start: 1498346

End: 1499314

Strand: Direct

Name: uvsE

Synonym: alr1263

Alternate gene names: 17228758

Gene position: 1498346-1499314 (Clockwise)

Preceding gene: 17228756

Following gene: 17228759

Centisome position: 23.36

GC content: 44.27

Gene sequence:

>969_bases
GTGGTAACAATAGATAATTCAATGACTGCAACCCAGTTAAACGACCTGCCTCAAACGGCACAGTTACGAAAAAACGCTCA
ACCAGAGTTAGGACTGGTTTGCATTACATTTGATAAAAAAGTGCGCTTTCGGACAATGACGCGCACACGGTATTTAAAAC
TTTCTCTCGCTCAACGTGAAAGCAGCTTAAGAGAAATATATCTGCATAACTTGCAGTGCTTACATGATGCCCTCACATTT
TGCCAGGAAAACAATCTTCGCCTGTATCGCATTTCCTCAGCTTTATTTCCCCTCAGCGATATGGAAGACCAAATTGGGAG
CAATATATTAGAAGAAATTAGCACTGATTTGGGGAAAATTGGTGAGCGATCGCAAGCTCTCAATATCAGAATGGTACTAC
ACCCAGATCAATATGTAGTCCTCAGTTCCGACTCTCCCGAAATCGTCCAAACTAGTATCAAAATCTTAGAACGGCACGCC
CGTACTTTCGACTTACTAGGCTTACCTCGTTCTCCTTGGTCATTGATGAACATTCACGGCGGTAAATCTCAACGTAGTGA
ACAACTAATCAAAGTCATCTCCAACCTGCCAGAAAACATCAAAAGCCGTTTGACATTAGAAAACGACGAATACGCTTACA
GCACCGAAGAAATATTCAACGTGTGCCAAAAAGCGCAAATACCAATGGTCTTCGATGCCCATCACCAAATTTGCCACGAA
AACCTAGATAGCTACGATCATCCCAGCGTCGCCGCCATGTTTTACGCCGCCAGAGAAACCTGGACAAACCCAGAATGGCA
ACTAGTCCATATTTCCAACGGCGAACAAGCATTCAACGATCGCAAACACAGCAATCTCATCACCAATATGCCCAACATCT
ATAGACAAGCGCCGTGGATAGAAGTCGAAGCCAAACACAAAGAAGTAGCGATCGCCCACTTGCGCTCATGGTGGCTTATG
GGACAATAG

Upstream 100 bases:

>100_bases
TGTTTTTACTGTGCGAGTACAAAATTTATATCTCATAGCTTCTCCAAGCTGAGGCTTTAGATACTATCCACCCATTGAGA
AAAATAAGTGTAATAAAACA

Downstream 100 bases:

>100_bases
TTCTTTGATATAAAAGCACTTTGTGATTTTGCGTTTTTGCGCGAACATAATAAAAGAATATGGCGATCGCGATTGACTTT
GGTACAAGTAACACCGTAAT

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MVTIDNSMTATQLNDLPQTAQLRKNAQPELGLVCITFDKKVRFRTMTRTRYLKLSLAQRESSLREIYLHNLQCLHDALTF
CQENNLRLYRISSALFPLSDMEDQIGSNILEEISTDLGKIGERSQALNIRMVLHPDQYVVLSSDSPEIVQTSIKILERHA
RTFDLLGLPRSPWSLMNIHGGKSQRSEQLIKVISNLPENIKSRLTLENDEYAYSTEEIFNVCQKAQIPMVFDAHHQICHE
NLDSYDHPSVAAMFYAARETWTNPEWQLVHISNGEQAFNDRKHSNLITNMPNIYRQAPWIEVEAKHKEVAIAHLRSWWLM
GQ

Sequences:

>Translated_322_residues
MVTIDNSMTATQLNDLPQTAQLRKNAQPELGLVCITFDKKVRFRTMTRTRYLKLSLAQRESSLREIYLHNLQCLHDALTF
CQENNLRLYRISSALFPLSDMEDQIGSNILEEISTDLGKIGERSQALNIRMVLHPDQYVVLSSDSPEIVQTSIKILERHA
RTFDLLGLPRSPWSLMNIHGGKSQRSEQLIKVISNLPENIKSRLTLENDEYAYSTEEIFNVCQKAQIPMVFDAHHQICHE
NLDSYDHPSVAAMFYAARETWTNPEWQLVHISNGEQAFNDRKHSNLITNMPNIYRQAPWIEVEAKHKEVAIAHLRSWWLM
GQ
>Mature_322_residues
MVTIDNSMTATQLNDLPQTAQLRKNAQPELGLVCITFDKKVRFRTMTRTRYLKLSLAQRESSLREIYLHNLQCLHDALTF
CQENNLRLYRISSALFPLSDMEDQIGSNILEEISTDLGKIGERSQALNIRMVLHPDQYVVLSSDSPEIVQTSIKILERHA
RTFDLLGLPRSPWSLMNIHGGKSQRSEQLIKVISNLPENIKSRLTLENDEYAYSTEEIFNVCQKAQIPMVFDAHHQICHE
NLDSYDHPSVAAMFYAARETWTNPEWQLVHISNGEQAFNDRKHSNLITNMPNIYRQAPWIEVEAKHKEVAIAHLRSWWLM
GQ

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVSE_NOSS1 (Q8YXF0)

Other databases:

- EMBL:   BA000019
- PIR:   AD1964
- RefSeq:   NP_485306.1
- ProteinModelPortal:   Q8YXF0
- SMR:   Q8YXF0
- STRING:   Q8YXF0
- GeneID:   1104858
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr1263
- NMPDR:   fig|103690.1.peg.1573
- eggNOG:   COG4294
- HOGENOM:   HBG456662
- OMA:   VFDAHHH
- ProtClustDB:   PRK02308
- BioCyc:   NSP103690:ALR1263-MONOMER
- HAMAP:   MF_00606
- InterPro:   IPR004601
- TIGRFAMs:   TIGR00629

Pfam domain/function: PF03851 UvdE

EC number: NA

Molecular weight: Translated: 37228; Mature: 37228

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTIDNSMTATQLNDLPQTAQLRKNAQPELGLVCITFDKKVRFRTMTRTRYLKLSLAQRE
CEEECCCCCHHHHHCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
SSLREIYLHNLQCLHDALTFCQENNLRLYRISSALFPLSDMEDQIGSNILEEISTDLGKI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GERSQALNIRMVLHPDQYVVLSSDSPEIVQTSIKILERHARTFDLLGLPRSPWSLMNIHG
CCCCCEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECC
GKSQRSEQLIKVISNLPENIKSRLTLENDEYAYSTEEIFNVCQKAQIPMVFDAHHQICHE
CCCHHHHHHHHHHHHCCHHHHHCEEECCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHH
NLDSYDHPSVAAMFYAARETWTNPEWQLVHISNGEQAFNDRKHSNLITNMPNIYRQAPWI
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCHHHCCHHHCCCHHHHCCCCE
EVEAKHKEVAIAHLRSWWLMGQ
EEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVTIDNSMTATQLNDLPQTAQLRKNAQPELGLVCITFDKKVRFRTMTRTRYLKLSLAQRE
CEEECCCCCHHHHHCCCHHHHHHHCCCCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHH
SSLREIYLHNLQCLHDALTFCQENNLRLYRISSALFPLSDMEDQIGSNILEEISTDLGKI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GERSQALNIRMVLHPDQYVVLSSDSPEIVQTSIKILERHARTFDLLGLPRSPWSLMNIHG
CCCCCEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECC
GKSQRSEQLIKVISNLPENIKSRLTLENDEYAYSTEEIFNVCQKAQIPMVFDAHHQICHE
CCCHHHHHHHHHHHHCCHHHHHCEEECCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHH
NLDSYDHPSVAAMFYAARETWTNPEWQLVHISNGEQAFNDRKHSNLITNMPNIYRQAPWI
HCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCHHHCCHHHCCCHHHHCCCCE
EVEAKHKEVAIAHLRSWWLMGQ
EEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840