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The map label for this gene is aroK [H]

Identifier: 17228739

GI number: 17228739

Start: 1478704

End: 1479249

Strand: Direct

Name: aroK [H]

Synonym: alr1244

Alternate gene names: 17228739

Gene position: 1478704-1479249 (Clockwise)

Preceding gene: 17228737

Following gene: 17228740

Centisome position: 23.06

GC content: 43.59

Gene sequence:

>546_bases
GTGAGTAGTTTATTGCAGGGAGTTAACCTATACTTAATCGGCATGATGGGCGCTGGTAAGACTACAGTAGGACATTTACT
CGCCAAAGAATTGGGTTATGGCTTTTTAGATACTGATAATGTGATTGCCCAAGCTACTAAAAAATCTATCAATGAGATAT
TTGCCGAAGCAGGGGAAGCCGGATTTCGCCAGATAGAAAGCGATGTGTTAGCCCAGGTTTGTTCCTATACTAAGTTGACT
GTAGCGACAGGTGGCGGCATTGTGTTGCGGCGAGAAAATTGGAGTTACCTACACCACGGTTTAATTTTGTGGCTAGATGT
GCCAGTAGATATACTCTATGCACGTTTAGCGGCAGATACAACAAGACCACTTTTACAGGATGATGACCCAAAAGGCAAAT
TGCGATCGCTCCTGGAACAACGCACACCGCTTTATTCGCAAGCAGATTTACGCATCTGTGTCAATGCAGAAGAAACACCA
GAACAAATTGCCAATAAAGTTATGCAGGCAATTCCCAGCGTCTTGAAACAAACTGCCTCTAATTAG

Upstream 100 bases:

>100_bases
GGCAAGGCTGATTGTATTATGGTTTCTTGAGCATCACCCATCCTACTGGGGTTATTTTCAATCAACACAGCAGATTCTGA
TAACGGAGAATTAAACAAGA

Downstream 100 bases:

>100_bases
TTAGGACTTACGCACCCAGATTTTCTGTTGAGGCTGGGTGTAAGGGTGTAGGGGTGTAAGGGTTTCAAACATTTATACCC
CTACACCCCTATACCCCTAT

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSSLLQGVNLYLIGMMGAGKTTVGHLLAKELGYGFLDTDNVIAQATKKSINEIFAEAGEAGFRQIESDVLAQVCSYTKLT
VATGGGIVLRRENWSYLHHGLILWLDVPVDILYARLAADTTRPLLQDDDPKGKLRSLLEQRTPLYSQADLRICVNAEETP
EQIANKVMQAIPSVLKQTASN

Sequences:

>Translated_181_residues
MSSLLQGVNLYLIGMMGAGKTTVGHLLAKELGYGFLDTDNVIAQATKKSINEIFAEAGEAGFRQIESDVLAQVCSYTKLT
VATGGGIVLRRENWSYLHHGLILWLDVPVDILYARLAADTTRPLLQDDDPKGKLRSLLEQRTPLYSQADLRICVNAEETP
EQIANKVMQAIPSVLKQTASN
>Mature_180_residues
SSLLQGVNLYLIGMMGAGKTTVGHLLAKELGYGFLDTDNVIAQATKKSINEIFAEAGEAGFRQIESDVLAQVCSYTKLTV
ATGGGIVLRRENWSYLHHGLILWLDVPVDILYARLAADTTRPLLQDDDPKGKLRSLLEQRTPLYSQADLRICVNAEETPE
QIANKVMQAIPSVLKQTASN

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Homo sapiens, GI153792148, Length=171, Percent_Identity=29.2397660818713, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=33.9285714285714, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI1786587, Length=166, Percent_Identity=33.7349397590361, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19816; Mature: 19685

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLQGVNLYLIGMMGAGKTTVGHLLAKELGYGFLDTDNVIAQATKKSINEIFAEAGEA
CCHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFRQIESDVLAQVCSYTKLTVATGGGIVLRRENWSYLHHGLILWLDVPVDILYARLAADT
HHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCHHHHCCCCEEEECCHHHHHHHHHHHH
TRPLLQDDDPKGKLRSLLEQRTPLYSQADLRICVNAEETPEQIANKVMQAIPSVLKQTAS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
N
C
>Mature Secondary Structure 
SSLLQGVNLYLIGMMGAGKTTVGHLLAKELGYGFLDTDNVIAQATKKSINEIFAEAGEA
CHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFRQIESDVLAQVCSYTKLTVATGGGIVLRRENWSYLHHGLILWLDVPVDILYARLAADT
HHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCHHHHCCCCEEEECCHHHHHHHHHHHH
TRPLLQDDDPKGKLRSLLEQRTPLYSQADLRICVNAEETPEQIANKVMQAIPSVLKQTAS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA