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The map label for this gene is argB [H]

Identifier: 17228740

GI number: 17228740

Start: 1479485

End: 1480378

Strand: Direct

Name: argB [H]

Synonym: alr1245

Alternate gene names: 17228740

Gene position: 1479485-1480378 (Clockwise)

Preceding gene: 17228739

Following gene: 17228741

Centisome position: 23.07

GC content: 44.97

Gene sequence:

>894_bases
ATGATGGTCAACGATATTGAGTATATCAGGCAAGCTGAAGCTACTCGTGTGCAGGTACTAAGCGAAGCACTACCTTATAT
TCAACAATTTGCCGGTCGCACCGTTGTTGTTAAATATGGTGGTGCGGCTATGAAAGATAGCCACCTCAAAGACCAAGTTA
TCCGCGATATTGTCTTTCTATCCTGCGTTGGGTTGCGGCCAATCTTGGTACATGGTGGCGGCCCGGAAATTAACAGTTGG
TTAGATAAGCTGGGAATCGAAGCACAGTTTAAAAACGGTCTACGAGTCACTGATGCTCCCACAATGGATGTGGTGGAAAT
GGTATTGGTAGGTCGAGTTAATAAAGAAATTGTCTCTCTAATTAACCAAGCTGGCGGCTTGGCAGTAGGGCTTTGTGGTA
AAGATGGTAACTTAATTACTGCCCGTCCCCAAGGTCAAGAGGGCATTGGTTTTGTCGGGGAAGTAAGTAACGTTAACATC
AAAATTTTGGAAACTTTAGCCAGTAACGGCTATATTCCCGTTGTTTCCAGCGTTGCCGCCGATGACTCAGGACAGGCTTA
TAATATTAACGCCGATACTGTGGCTGGTGAAATTGCTGCCGCCTTAGGGGCGGAAAAACTGATTTTATTAACGGATACCA
GAGGTATTTTAAAAGATTATCAAGACCCTGGAACATTGATTCCCAAAGTAGATATTCGGGAAGCCCGCGAATTAATTAAT
AGTGGTGTTGTTAGCGGTGGGATGATCCCCAAGGTTACTTGTTGTGTGCGATCGCTCGCTCAAGGAGTCAGAGCCGCACA
CATCATAGACGGTCGTATTCCCCACGCCTTACTACTGGAAATTTTTACTGATGTGGGTATTGGGACAATGATTCTCGGTT
CTCAGTATAGTTAA

Upstream 100 bases:

>100_bases
CGTAAGTCCTATTAGTAATTCATAATTCGTAATTCGCAATGAAAGCAACAATTAGGAATTATACTGACTGGATAAATATA
TAAGTTTCCACGGCTCCTCA

Downstream 100 bases:

>100_bases
TTTATAAGGGTATGGGTAATGGGTACTGGGTAATAGGGGCTAATCTTCCCCCCCCCACCCCCCACTCCCTATTTTCCAGT
TAGTGCTGATCGGTGGGCAA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MMVNDIEYIRQAEATRVQVLSEALPYIQQFAGRTVVVKYGGAAMKDSHLKDQVIRDIVFLSCVGLRPILVHGGGPEINSW
LDKLGIEAQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVSLINQAGGLAVGLCGKDGNLITARPQGQEGIGFVGEVSNVNI
KILETLASNGYIPVVSSVAADDSGQAYNINADTVAGEIAAALGAEKLILLTDTRGILKDYQDPGTLIPKVDIREARELIN
SGVVSGGMIPKVTCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQYS

Sequences:

>Translated_297_residues
MMVNDIEYIRQAEATRVQVLSEALPYIQQFAGRTVVVKYGGAAMKDSHLKDQVIRDIVFLSCVGLRPILVHGGGPEINSW
LDKLGIEAQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVSLINQAGGLAVGLCGKDGNLITARPQGQEGIGFVGEVSNVNI
KILETLASNGYIPVVSSVAADDSGQAYNINADTVAGEIAAALGAEKLILLTDTRGILKDYQDPGTLIPKVDIREARELIN
SGVVSGGMIPKVTCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQYS
>Mature_297_residues
MMVNDIEYIRQAEATRVQVLSEALPYIQQFAGRTVVVKYGGAAMKDSHLKDQVIRDIVFLSCVGLRPILVHGGGPEINSW
LDKLGIEAQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVSLINQAGGLAVGLCGKDGNLITARPQGQEGIGFVGEVSNVNI
KILETLASNGYIPVVSSVAADDSGQAYNINADTVAGEIAAALGAEKLILLTDTRGILKDYQDPGTLIPKVDIREARELIN
SGVVSGGMIPKVTCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQYS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI145693208, Length=260, Percent_Identity=34.2307692307692, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789181, Length=299, Percent_Identity=26.0869565217391, Blast_Score=104, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320913, Length=265, Percent_Identity=31.3207547169811, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31560; Mature: 31560

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVNDIEYIRQAEATRVQVLSEALPYIQQFAGRTVVVKYGGAAMKDSHLKDQVIRDIVFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
SCVGLRPILVHGGGPEINSWLDKLGIEAQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVSL
HHHCCCEEEEECCCCCHHHHHHHHCCEEECCCCCEECCCCHHHHHHHHHHCCCCHHHHHH
INQAGGLAVGLCGKDGNLITARPQGQEGIGFVGEVSNVNIKILETLASNGYIPVVSSVAA
HHHCCCEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCCEEEEHHHCCCCEEEHHHHCC
DDSGQAYNINADTVAGEIAAALGAEKLILLTDTRGILKDYQDPGTLIPKVDIREARELIN
CCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHH
SGVVSGGMIPKVTCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQYS
CCCCCCCCHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHCCCCCEECCCCCC
>Mature Secondary Structure
MMVNDIEYIRQAEATRVQVLSEALPYIQQFAGRTVVVKYGGAAMKDSHLKDQVIRDIVFL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
SCVGLRPILVHGGGPEINSWLDKLGIEAQFKNGLRVTDAPTMDVVEMVLVGRVNKEIVSL
HHHCCCEEEEECCCCCHHHHHHHHCCEEECCCCCEECCCCHHHHHHHHHHCCCCHHHHHH
INQAGGLAVGLCGKDGNLITARPQGQEGIGFVGEVSNVNIKILETLASNGYIPVVSSVAA
HHHCCCEEEEEECCCCCEEEECCCCCCCCCEEEECCCCCCEEEEHHHCCCCEEEHHHHCC
DDSGQAYNINADTVAGEIAAALGAEKLILLTDTRGILKDYQDPGTLIPKVDIREARELIN
CCCCCEEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHH
SGVVSGGMIPKVTCCVRSLAQGVRAAHIIDGRIPHALLLEIFTDVGIGTMILGSQYS
CCCCCCCCHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHCCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA