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The map label for this gene is yciR [C]

Identifier: 17228725

GI number: 17228725

Start: 1456204

End: 1457415

Strand: Direct

Name: yciR [C]

Synonym: alr1230

Alternate gene names: 17228725

Gene position: 1456204-1457415 (Clockwise)

Preceding gene: 17228724

Following gene: 17228726

Centisome position: 22.7

GC content: 34.65

Gene sequence:

>1212_bases
ATGATTAAAATTTTAGTAATTGAAGATGAAGAATCAGTCAGGGAAAATATTTTAGATTTGCTACAAGCTGAAGATTTTCA
TACCGTGTCTGCTGCTAATGGACGCATTGGCATAAATTTAGCATTGGCAGAATTTCCTGATTTAATTTTGTGCGATATGA
TGATGCCCGAAGTTGATGGTTATGGGGTATTATCAGCATTACGCCAAGAACCATTAACGGCAACAATTCCTTTCATTTTC
CTCACGGCAAAATCTGCCAAAGCAGATTTCCGCCAAGGTATGGATATGGGGGCAGATGACTACCTAACTAAACCATTTAC
CAGGGCAGAATTACTCAGTGCTGTGATGAATCGTTTAGAAAGACAAGCCACTTTAAAAAAGTACTTAATCAATCACAATG
GCATTAAAGTCTCATCTCCAAAAACTCAGTTGCTAGAGATGAGTCTACATAAAGTTATTCAACAACAAAAATTTCCAGAG
TTTGAGGTGCAATATCAGCCTATCGTTGATATTGCTTCAGGAAAAATAGTTGCAGCAGAAAGTTTATTACGTTGGAACAG
TCCTGAATTAGGTTTTGTTTCCCCTTCGGAATTTATTCCATTAGCAGAGTCTACAGGTTTAATTGTGCCAATTGGTCAAT
GGGTAATAGCTAATGTTTGTCACCAAATCAAAAGTTGGCATGATTCTGGAGTGGATTTCTTAACCATTTCTGTGAATTTA
TCAGCAATGGAATTTAATAAACCAGATTTAATTCAGAGAATTACTGAAGCTTTAAAAAGCAATAATATAGCACCACATTA
TTTGGAAATAGAATTAACTGAAAGCATGATTATGCAAGACCTAAATAGTGCAATTTTCACCATGAATGAATTGCAATCTC
TAGGTGTTAGGCTTGCTATTGATGACTTTGGTACAGGTTACTCTTCTTTGATTTATCTCAAAAATTTGCCAGTTAATACA
CTGAAAATTGACAGGTACTTTATTCATAATGTTGCTAAGGATAAACAAAAATCTGCCATTACCAAAGCTTTAATAGAAAT
GGCACACAATATGAATATGCAAGTAGTGGCTGAAGGTGTAGAAACAGAATCAGAACTATACTTTTTAAAGCAAAATAAAT
GTGATGCCATGCAAGGATTTCTCTTTAGTCGTCCATTACCAGCAGTAGAATTTGAAAATTTTCTGTGGAATAATAAACAT
TTGTCTGTATAA

Upstream 100 bases:

>100_bases
ATTCATCAAGGTGAAATATCTGTTTCTAGTAACCCAGAAGTTGGTACTCTATTTACTGTGAATATTCCTTTAAAACAATC
AATAAACGAAGAGGTCAAAA

Downstream 100 bases:

>100_bases
AAAATAGCCAAATGACCACTACCGTTAACCAAACGTTAACTCGATAATTACTAAAATATAGTGATAGTTGCTTTTTGGTA
ATTTTTTTATAAACAAAGAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLILCDMMMPEVDGYGVLSALRQEPLTATIPFIF
LTAKSAKADFRQGMDMGADDYLTKPFTRAELLSAVMNRLERQATLKKYLINHNGIKVSSPKTQLLEMSLHKVIQQQKFPE
FEVQYQPIVDIASGKIVAAESLLRWNSPELGFVSPSEFIPLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNL
SAMEFNKPDLIQRITEALKSNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAIDDFGTGYSSLIYLKNLPVNT
LKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGVETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKH
LSV

Sequences:

>Translated_403_residues
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLILCDMMMPEVDGYGVLSALRQEPLTATIPFIF
LTAKSAKADFRQGMDMGADDYLTKPFTRAELLSAVMNRLERQATLKKYLINHNGIKVSSPKTQLLEMSLHKVIQQQKFPE
FEVQYQPIVDIASGKIVAAESLLRWNSPELGFVSPSEFIPLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNL
SAMEFNKPDLIQRITEALKSNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAIDDFGTGYSSLIYLKNLPVNT
LKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGVETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKH
LSV
>Mature_403_residues
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLILCDMMMPEVDGYGVLSALRQEPLTATIPFIF
LTAKSAKADFRQGMDMGADDYLTKPFTRAELLSAVMNRLERQATLKKYLINHNGIKVSSPKTQLLEMSLHKVIQQQKFPE
FEVQYQPIVDIASGKIVAAESLLRWNSPELGFVSPSEFIPLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNL
SAMEFNKPDLIQRITEALKSNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAIDDFGTGYSSLIYLKNLPVNT
LKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGVETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKH
LSV

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=257, Percent_Identity=35.7976653696498, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87081921, Length=236, Percent_Identity=38.9830508474576, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI226510982, Length=236, Percent_Identity=38.5593220338983, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790496, Length=231, Percent_Identity=35.9307359307359, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI87081980, Length=236, Percent_Identity=34.3220338983051, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=36.25, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=32.6359832635983, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=34.6613545816733, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787055, Length=226, Percent_Identity=33.1858407079646, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786507, Length=235, Percent_Identity=30.6382978723404, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=31.0204081632653, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082096, Length=197, Percent_Identity=28.4263959390863, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=39.1666666666667, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787410, Length=224, Percent_Identity=28.125, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082012, Length=138, Percent_Identity=36.231884057971, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786784, Length=124, Percent_Identity=37.0967741935484, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786911, Length=168, Percent_Identity=29.7619047619048, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788394, Length=119, Percent_Identity=31.9327731092437, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789809, Length=121, Percent_Identity=35.5371900826446, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790860, Length=118, Percent_Identity=30.5084745762712, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=136, Percent_Identity=31.6176470588235, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790552, Length=121, Percent_Identity=32.2314049586777, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367329, Length=158, Percent_Identity=34.1772151898734, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790863, Length=123, Percent_Identity=31.7073170731707, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789402, Length=126, Percent_Identity=32.5396825396825, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 45387; Mature: 45387

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLILCDMMMPEVDG
CEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEHHHCCCHHHHHHHCCCCCC
YGVLSALRQEPLTATIPFIFLTAKSAKADFRQGMDMGADDYLTKPFTRAELLSAVMNRLE
HHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHH
RQATLKKYLINHNGIKVSSPKTQLLEMSLHKVIQQQKFPEFEVQYQPIVDIASGKIVAAE
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCEEEHH
SLLRWNSPELGFVSPSEFIPLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNL
HHHHCCCCCCCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
SAMEFNKPDLIQRITEALKSNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAI
EEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTGYSSLIYLKNLPVNTLKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGV
ECCCCCHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
ETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKHLSV
CCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIKILVIEDEESVRENILDLLQAEDFHTVSAANGRIGINLALAEFPDLILCDMMMPEVDG
CEEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCEEEEEEEHHHCCCHHHHHHHCCCCCC
YGVLSALRQEPLTATIPFIFLTAKSAKADFRQGMDMGADDYLTKPFTRAELLSAVMNRLE
HHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHH
RQATLKKYLINHNGIKVSSPKTQLLEMSLHKVIQQQKFPEFEVQYQPIVDIASGKIVAAE
HHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCEEEHH
SLLRWNSPELGFVSPSEFIPLAESTGLIVPIGQWVIANVCHQIKSWHDSGVDFLTISVNL
HHHHCCCCCCCCCCHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
SAMEFNKPDLIQRITEALKSNNIAPHYLEIELTESMIMQDLNSAIFTMNELQSLGVRLAI
EEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTGYSSLIYLKNLPVNTLKIDRYFIHNVAKDKQKSAITKALIEMAHNMNMQVVAEGV
ECCCCCHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
ETESELYFLKQNKCDAMQGFLFSRPLPAVEFENFLWNNKHLSV
CCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]