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The map label for this gene is tcrA [H]

Identifier: 17228665

GI number: 17228665

Start: 1373561

End: 1374265

Strand: Direct

Name: tcrA [H]

Synonym: alr1170

Alternate gene names: 17228665

Gene position: 1373561-1374265 (Clockwise)

Preceding gene: 17228662

Following gene: 17228666

Centisome position: 21.42

GC content: 40.99

Gene sequence:

>705_bases
ATGAGGGTGCTACTAGTCGAAGATGAGCCAGATTTGGGGGCAGCGATTAAGCGTACTTTAAATCAGCAAAAGTACCTAGT
TGACTGGGTTATGGATGGGAATGACGCATGGACTTACTTAGAAAATAGTTCGGCGCAATATACAGTAGTGATTCTTGATT
GGATGCTTCCAGGAATTAGTGGTTTAGAATTGTGTAAAAGACTGCGTTATCAAGGTAATCCTCTTCCTATCCTGATGCTA
ACTGCCAAAGATAGAATGGAAGATAAAGTTGCCGGACTAGATGCAGGTGCCGATGACTACTTAGTAAAGCCTTTCGGTAT
GGTGGAACTGCTGGCACGATTGCGAGCTTTGCAACGTCGTTCTCCACACTTACAACCCCAACAATTAACTGTTGGTAACT
TCACCCTAGATTACGGCAACAGTACAGTTGTTAGACAAAATACAACAGGTGAACAGCAAAGTATTCCATTAACTAATAAA
GAATTCCAACTATTGGAATATTTCATGAACCATCCTCACCAAATTGTGACAACTGAGCAAATTCGTAATCAAATTTGGGA
AGTTAATGCGGAATCTAGCAGTAATGTAGTAGCGGCCCAAATACGCTTGTTACGTCGTAAACTCACAAGTAACGACTGTC
CTAATCCAATTGAAACTCTGCACGGTATGGGGTATCGTCTTAAGTTCTCAGATGAATCAAAATAA

Upstream 100 bases:

>100_bases
AATTTCATAAATTTCTGCAAACCTATTAATAAGGGTGTCCCTATGGCGAACTATACTAAAGCCAAAAATTTACAACGAAA
TTTCAAATACTCAGTTTGAT

Downstream 100 bases:

>100_bases
ACTGTTTCGGCTTACCCGTGTTCGTTTAGCTCTGTATTACGCTATTGTTATGGGTTTGATTTTAAGCCTATCTGCTTTTA
GCTTTTATAGGTCTGTGTTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRVLLVEDEPDLGAAIKRTLNQQKYLVDWVMDGNDAWTYLENSSAQYTVVILDWMLPGISGLELCKRLRYQGNPLPILML
TAKDRMEDKVAGLDAGADDYLVKPFGMVELLARLRALQRRSPHLQPQQLTVGNFTLDYGNSTVVRQNTTGEQQSIPLTNK
EFQLLEYFMNHPHQIVTTEQIRNQIWEVNAESSSNVVAAQIRLLRRKLTSNDCPNPIETLHGMGYRLKFSDESK

Sequences:

>Translated_234_residues
MRVLLVEDEPDLGAAIKRTLNQQKYLVDWVMDGNDAWTYLENSSAQYTVVILDWMLPGISGLELCKRLRYQGNPLPILML
TAKDRMEDKVAGLDAGADDYLVKPFGMVELLARLRALQRRSPHLQPQQLTVGNFTLDYGNSTVVRQNTTGEQQSIPLTNK
EFQLLEYFMNHPHQIVTTEQIRNQIWEVNAESSSNVVAAQIRLLRRKLTSNDCPNPIETLHGMGYRLKFSDESK
>Mature_234_residues
MRVLLVEDEPDLGAAIKRTLNQQKYLVDWVMDGNDAWTYLENSSAQYTVVILDWMLPGISGLELCKRLRYQGNPLPILML
TAKDRMEDKVAGLDAGADDYLVKPFGMVELLARLRALQRRSPHLQPQQLTVGNFTLDYGNSTVVRQNTTGEQQSIPLTNK
EFQLLEYFMNHPHQIVTTEQIRNQIWEVNAESSSNVVAAQIRLLRRKLTSNDCPNPIETLHGMGYRLKFSDESK

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=36.6379310344828, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=38.3259911894273, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=39.9122807017544, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.4827586206897, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=38.6266094420601, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.061135371179, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=32.4561403508772, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.9130434782609, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=237, Percent_Identity=35.4430379746835, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.4763948497854, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=29.1845493562232, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=28.1512605042017, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26720; Mature: 26720

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDEPDLGAAIKRTLNQQKYLVDWVMDGNDAWTYLENSSAQYTVVILDWMLPGIS
CEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCC
GLELCKRLRYQGNPLPILMLTAKDRMEDKVAGLDAGADDYLVKPFGMVELLARLRALQRR
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHC
SPHLQPQQLTVGNFTLDYGNSTVVRQNTTGEQQSIPLTNKEFQLLEYFMNHPHQIVTTEQ
CCCCCCCEEEECEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHH
IRNQIWEVNAESSSNVVAAQIRLLRRKLTSNDCPNPIETLHGMGYRLKFSDESK
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure
MRVLLVEDEPDLGAAIKRTLNQQKYLVDWVMDGNDAWTYLENSSAQYTVVILDWMLPGIS
CEEEEECCCCCHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCEEEEEEEECCCCCCC
GLELCKRLRYQGNPLPILMLTAKDRMEDKVAGLDAGADDYLVKPFGMVELLARLRALQRR
HHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHC
SPHLQPQQLTVGNFTLDYGNSTVVRQNTTGEQQSIPLTNKEFQLLEYFMNHPHQIVTTEQ
CCCCCCCEEEECEEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEHHH
IRNQIWEVNAESSSNVVAAQIRLLRRKLTSNDCPNPIETLHGMGYRLKFSDESK
HHHHHEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]