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The map label for this gene is yqcK [H]

Identifier: 17228599

GI number: 17228599

Start: 1293372

End: 1293824

Strand: Direct

Name: yqcK [H]

Synonym: alr1104

Alternate gene names: 17228599

Gene position: 1293372-1293824 (Clockwise)

Preceding gene: 17228597

Following gene: 17228600

Centisome position: 20.17

GC content: 38.41

Gene sequence:

>453_bases
ATGTCCGTTATGAAAACACACGTAGCCTTAAATGTCACCAATATTGAGAAGTCTGTAACATTTTATAGAGCCATGTTTGG
CTTAGAACCAGTCAAGTATAAAACCGACTACGCTAAATTTGATATTCCTAACCCAGCCTTAAACCTGACACTGAATTTAA
CTAATAATGTGCAGATTGGTGGTGCATTGTCTCATTTAGGTGTACAAGTTGAAAGTACTCAAGAAGTACAATCAGCTATC
GAACGATTTAACGAAGCAGGACTAGATTTATTTACAGAGGATAATACTGATTGTTGCTACGCTTTACAAGACAAAGTATG
GGTAACAGATCCAGATGGGAACCGTTGGGAAGTTTTTGTGGTAAAAGTAGCAGATACAGCGCCAGAAAAGAATCTTGCAA
CAGTAAGTTCTTCTGGGGAAATTCAGGCTGTCAAGAAGTCATGTTGTGCTTAG

Upstream 100 bases:

>100_bases
CATACTTTTATATTGACATCTATCAATATATCTGGCAACATATTGATGAAGACAAATATTGATAGATATCAATATTTAAA
TATTACTAGGAGAAAAACTC

Downstream 100 bases:

>100_bases
ATAATAACGATATTTAACAGAGGCGAAAATCGTCTCTGTTTATCTTCTGTAAGAGGGAGAAATCATGAAAAAAGTAATGT
TTGTATGTAAACATAATTCT

Product: hypothetical protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSVMKTHVALNVTNIEKSVTFYRAMFGLEPVKYKTDYAKFDIPNPALNLTLNLTNNVQIGGALSHLGVQVESTQEVQSAI
ERFNEAGLDLFTEDNTDCCYALQDKVWVTDPDGNRWEVFVVKVADTAPEKNLATVSSSGEIQAVKKSCCA

Sequences:

>Translated_150_residues
MSVMKTHVALNVTNIEKSVTFYRAMFGLEPVKYKTDYAKFDIPNPALNLTLNLTNNVQIGGALSHLGVQVESTQEVQSAI
ERFNEAGLDLFTEDNTDCCYALQDKVWVTDPDGNRWEVFVVKVADTAPEKNLATVSSSGEIQAVKKSCCA
>Mature_149_residues
SVMKTHVALNVTNIEKSVTFYRAMFGLEPVKYKTDYAKFDIPNPALNLTLNLTNNVQIGGALSHLGVQVESTQEVQSAIE
RFNEAGLDLFTEDNTDCCYALQDKVWVTDPDGNRWEVFVVKVADTAPEKNLATVSSSGEIQAVKKSCCA

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2641 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 16523; Mature: 16392

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00934 GLYOXALASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMKTHVALNVTNIEKSVTFYRAMFGLEPVKYKTDYAKFDIPNPALNLTLNLTNNVQIG
CCCEEEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCEEEEEEECCCEEEC
GALSHLGVQVESTQEVQSAIERFNEAGLDLFTEDNTDCCYALQDKVWVTDPDGNRWEVFV
CCHHHHEEEEECHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECEEEEECCCCCEEEEEE
VKVADTAPEKNLATVSSSGEIQAVKKSCCA
EEEECCCCCCCEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SVMKTHVALNVTNIEKSVTFYRAMFGLEPVKYKTDYAKFDIPNPALNLTLNLTNNVQIG
CCEEEEEEEEEECCHHHHHHHHHHHCCCCCEEECCCEEEECCCCCEEEEEEECCCEEEC
GALSHLGVQVESTQEVQSAIERFNEAGLDLFTEDNTDCCYALQDKVWVTDPDGNRWEVFV
CCHHHHEEEEECHHHHHHHHHHHHHCCCEEEECCCCCEEEEEECEEEEECCCCCEEEEEE
VKVADTAPEKNLATVSSSGEIQAVKKSCCA
EEEECCCCCCCEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895 [H]