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The map label for this gene is arsC [H]

Identifier: 17228600

GI number: 17228600

Start: 1293889

End: 1294284

Strand: Direct

Name: arsC [H]

Synonym: alr1105

Alternate gene names: 17228600

Gene position: 1293889-1294284 (Clockwise)

Preceding gene: 17228599

Following gene: 17228602

Centisome position: 20.17

GC content: 36.62

Gene sequence:

>396_bases
ATGAAAAAAGTAATGTTTGTATGTAAACATAATTCTCGGCGATCGCAAATGGCAGAGGGCTTTACTAAAATATTAGGTAA
AGATAATATCGCTGTGACTAGTGCAGGTTTAGCCGTTAGTCAGATAGATCCATTTGCCATAGAAGTCATGTCAGAAATTG
GGATTGATATTAGTAACCAGACTTCTAAGCCTTTAGAAAATTTCCATCCAGAAGAGTATGACGCAGTAATTTCCTTATGT
GGTTGCGGTATGAATTTACCAGAAGCTTGGGTATTACGAGATATATTTGAAGATTGGCAACTTGATGATCCTCAAGGAGA
ATCTATAGAAACTTTTCGCCGTGTGCGTGATGAGATTAAAGAAAGAGTGGTAAAGTTAATCGCATTACTCAACTAA

Upstream 100 bases:

>100_bases
GAAATTCAGGCTGTCAAGAAGTCATGTTGTGCTTAGATAATAACGATATTTAACAGAGGCGAAAATCGTCTCTGTTTATC
TTCTGTAAGAGGGAGAAATC

Downstream 100 bases:

>100_bases
ATCAAAGCCTTTTGATTAACGCTTCTAGTACTAAACTGTATTTAATTAGGAGATAGGAAAGAATTTCTCCCTCATCTCCA
TCTCTGCGCCTCTACGTGAT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFAIEVMSEIGIDISNQTSKPLENFHPEEYDAVISLC
GCGMNLPEAWVLRDIFEDWQLDDPQGESIETFRRVRDEIKERVVKLIALLN

Sequences:

>Translated_131_residues
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFAIEVMSEIGIDISNQTSKPLENFHPEEYDAVISLC
GCGMNLPEAWVLRDIFEDWQLDDPQGESIETFRRVRDEIKERVVKLIALLN
>Mature_131_residues
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFAIEVMSEIGIDISNQTSKPLENFHPEEYDAVISLC
GCGMNLPEAWVLRDIFEDWQLDDPQGESIETFRRVRDEIKERVVKLIALLN

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 14828; Mature: 14828

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFAIEVMSEIGIDISNQ
CCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHCCCCCCC
TSKPLENFHPEEYDAVISLCGCGMNLPEAWVLRDIFEDWQLDDPQGESIETFRRVRDEIK
CCCCHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ERVVKLIALLN
HHHHHHHHHCC
>Mature Secondary Structure
MKKVMFVCKHNSRRSQMAEGFTKILGKDNIAVTSAGLAVSQIDPFAIEVMSEIGIDISNQ
CCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCHHHHHHHHHHCCCCCCC
TSKPLENFHPEEYDAVISLCGCGMNLPEAWVLRDIFEDWQLDDPQGESIETFRRVRDEIK
CCCCHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ERVVKLIALLN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA