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The map label for this gene is coxC [H]

Identifier: 17228447

GI number: 17228447

Start: 1107308

End: 1107931

Strand: Direct

Name: coxC [H]

Synonym: alr0952

Alternate gene names: 17228447

Gene position: 1107308-1107931 (Clockwise)

Preceding gene: 17228446

Following gene: 17228448

Centisome position: 17.26

GC content: 44.23

Gene sequence:

>624_bases
ATGCAAAGTCAAACTATTGACCCAGCGCAAACGGAACTAAATCATCACCACGCAGCCGAGGCGGTTGGTCATCACGAAGA
ACATCCTGATCATCGGCTGTTTGGGTTATTTGTCTTCCTAGTTGCCGAGGGAATGATATTTTTAGGTTTGTTCGGAGCAT
ATCTGGCCTTCCGTTCAACATTACCTGTATGGCCGCCGGCAGGTACACCAGAGTTAGAACTTTTACTTCCTGGTGTAAAT
ACTGTCAATCTAATTGCCAGCAGCTTTGTCATGCACAATGCTGATACTGCTATCAAGAAAAATGATACCAAGGGTATGCG
TCTGTGGTTGGCAATTACTGCCGCAATGGGTGCGATTTTCTTGGTCGGGCAGGTTTACGAATACACCCATTTAGAATTTG
GGCTGACTACTAATTTATTCGCTAGTGCGTTTTACGTGTTGACTGGTTTTCACGGACTGCACGTAACTATAGGCGTTTTG
GCAATTGTAGCTGTGTTGTGGCGATCGCGCACTCAAGGTCACTATAGTAGTGAAAAACACTTTGGTATTGAAGCTGCGGA
AATATACTGGCACTTTGTAGACGTAATCTGGATTATTCTGTTCGGATTACTGTACTTACTGTAA

Upstream 100 bases:

>100_bases
GTTTTACATTGCTTCTACTCCCCAATCCCCATTCCCCAACCCCCAGTCCCCAATCCCCAGTCCCCAATCCCCAATCCCCA
ATCCCCAATTTTTAAGATTC

Downstream 100 bases:

>100_bases
GTATTAATTATTTAGTTGTTCACTCCACGCGGACAACATAGATTTTAGCCCCCCTCTGGGGGTTTTTTTATTGGTGCAGT
GATCTTTTCAAGACTTATAC

Product: cytochrome c oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQSQTIDPAQTELNHHHAAEAVGHHEEHPDHRLFGLFVFLVAEGMIFLGLFGAYLAFRSTLPVWPPAGTPELELLLPGVN
TVNLIASSFVMHNADTAIKKNDTKGMRLWLAITAAMGAIFLVGQVYEYTHLEFGLTTNLFASAFYVLTGFHGLHVTIGVL
AIVAVLWRSRTQGHYSSEKHFGIEAAEIYWHFVDVIWIILFGLLYLL

Sequences:

>Translated_207_residues
MQSQTIDPAQTELNHHHAAEAVGHHEEHPDHRLFGLFVFLVAEGMIFLGLFGAYLAFRSTLPVWPPAGTPELELLLPGVN
TVNLIASSFVMHNADTAIKKNDTKGMRLWLAITAAMGAIFLVGQVYEYTHLEFGLTTNLFASAFYVLTGFHGLHVTIGVL
AIVAVLWRSRTQGHYSSEKHFGIEAAEIYWHFVDVIWIILFGLLYLL
>Mature_207_residues
MQSQTIDPAQTELNHHHAAEAVGHHEEHPDHRLFGLFVFLVAEGMIFLGLFGAYLAFRSTLPVWPPAGTPELELLLPGVN
TVNLIASSFVMHNADTAIKKNDTKGMRLWLAITAAMGAIFLVGQVYEYTHLEFGLTTNLFASAFYVLTGFHGLHVTIGVL
AIVAVLWRSRTQGHYSSEKHFGIEAAEIYWHFVDVIWIILFGLLYLL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=143, Percent_Identity=39.8601398601399, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1786633, Length=195, Percent_Identity=32.8205128205128, Blast_Score=90, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6226542, Length=180, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 23099; Mature: 23099

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQTIDPAQTELNHHHAAEAVGHHEEHPDHRLFGLFVFLVAEGMIFLGLFGAYLAFRST
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVWPPAGTPELELLLPGVNTVNLIASSFVMHNADTAIKKNDTKGMRLWLAITAAMGAIF
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHH
LVGQVYEYTHLEFGLTTNLFASAFYVLTGFHGLHVTIGVLAIVAVLWRSRTQGHYSSEKH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FGIEAAEIYWHFVDVIWIILFGLLYLL
CCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQSQTIDPAQTELNHHHAAEAVGHHEEHPDHRLFGLFVFLVAEGMIFLGLFGAYLAFRST
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVWPPAGTPELELLLPGVNTVNLIASSFVMHNADTAIKKNDTKGMRLWLAITAAMGAIF
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHH
LVGQVYEYTHLEFGLTTNLFASAFYVLTGFHGLHVTIGVLAIVAVLWRSRTQGHYSSEKH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FGIEAAEIYWHFVDVIWIILFGLLYLL
CCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8387368; 8905231 [H]