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The map label for this gene is lipB [H]

Identifier: 39546300

GI number: 39546300

Start: 697288

End: 697929

Strand: Reverse

Name: lipB [H]

Synonym: STM0635.S

Alternate gene names: 39546300

Gene position: 697929-697288 (Counterclockwise)

Preceding gene: 16764013

Following gene: 16764011

Centisome position: 14.37

GC content: 49.84

Gene sequence:

>642_bases
TTGTATCAGGATAAAATCCTTGTCCGCCAGCTCGGCCTTCAGCCCTATGAAGCTATCTCTCAGGCCATGCATAACTTTAC
CGATATGCGCGATGAAAACAGCCATGATGAAATCTGGTTGGTTGAGCATTACCCGGTGTTTACCCAGGGCCAGGCCGGTA
AAGCGGAACATATATTGATGCCTGGCGATATTCCCGTTGTGCAGAGCGATCGTGGAGGACAGGTGACCTATCATGGTCCG
GGCCAACAGGTAATGTACGTTTTACTTAACCTGAAACGACGTAAACTGGGCGTGCGTGATTTAGTCACCCTACTTGAACA
GACCGTGGTGAATACGCTGGCTGAAATTGGTATTGAGGCGCATCCGCGCGCCGATGCGCCGGGCGTCTACGTGGGTGAAA
AGAAAATCTGCTCGCTGGGTTTACGTATCCGTCGCGGCTGCTCATTCCACGGTTTAGCGCTAAACGTTAACATGGATCTT
TCTCCTTTCCTGCGTATCAACCCGTGTGGTTATGCCGGCATGGAAATGGCCAAAATAACGCAGTGGAAGGAAGATGCTAC
CACGGATAATATTGCGCCCCGCTTGCTGGCGAATATTTTAGCTCTGCTAAATAATCCACCGTATGAATATATTGCTGCTT
AA

Upstream 100 bases:

>100_bases
ATACATCCAGACGGTTACCCGGTCTTATCCGGGTAACTCCCCGCCTCCCCCGCTGTGATATACTTTCCTCTCTTTTTTCA
TTCTCTACGGAGATGCCGTT

Downstream 100 bases:

>100_bases
TGCGTAAAATATAATGGCCCAAGAAATTTATGGGTCATTAATCATATATGATTTGAATGCTTTACTTCTCCCCCCGCTTT
CTATATTTTCGTTATATCCC

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAA

Sequences:

>Translated_213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAA
>Mature_213_residues
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGP
GQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAA

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=132, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87081767, Length=213, Percent_Identity=91.5492957746479, Blast_Score=410, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6323268, Length=152, Percent_Identity=34.8684210526316, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355483, Length=147, Percent_Identity=34.6938775510204, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 23838; Mature: 23838

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00092 N6_MTASE ; PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILM
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCCCEEEE
PGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEA
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
HPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKIT
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHH
QWKEDATTDNIAPRLLANILALLNNPPYEYIAA
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHYPVFTQGQAGKAEHILM
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCCCCCCEEEE
PGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLVTLLEQTVVNTLAEIGIEA
CCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
HPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKIT
CCCCCCCCEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEECCCCCCCCHHHHHH
QWKEDATTDNIAPRLLANILALLNNPPYEYIAA
HHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA