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The map label for this gene is aas [H]

Identifier: 16766312

GI number: 16766312

Start: 3167872

End: 3170031

Strand: Reverse

Name: aas [H]

Synonym: STM3010

Alternate gene names: 16766312

Gene position: 3170031-3167872 (Counterclockwise)

Preceding gene: 16766315

Following gene: 16766311

Centisome position: 65.26

GC content: 55.05

Gene sequence:

>2160_bases
ATGCTGTTTGGATTTTTCCGTAACCTGTTTCGCGTGCTTTATCGTGTGCGCGTCACTGGCGATGTCCGGGCGCTACAGGG
GAACCGGGTCTTAATTACCCCCAATCACGTTTCATTTATCGATGGTATGCTACTGGCGCTGTTTTTGCCGGTACGGCCTG
TCTTTGCGGTATATACCTCCATCAGCCAGCAATGGTATATGCGCTGGTTAACGCCGCTGATCGATTTTGTGCCGCTCGAC
CCCACTAAACCCATGTCCATTAAACACCTGGTGCGTCTGGTGGAACAGGGGCGTCCAGTGGTGATTTTCCCGGAAGGGCG
GATTTCCGTGACCGGCTCGCTGATGAAAATTTATGACGGCGCAGGCTTTGTGGCGGCAAAATCGGGCGCAACCGTCATTC
CGCTCCGCATTGACGGCGCGGAGCTGACCCCTTTCAGTCGCCTGAAAGGTCTGGTTAAACGGCGCTTATTCCCCCGCATT
CAGCTTCATATTTTACCGCCGACGCAAATACCGATGCCGGAAGCGCCGCGCGCGCGCGACAGACGTAAGATAGCGGGTGA
GATGCTGCACCAGATCATGATGGAAGCGCGTATGGCGGTGCGCCCGCGCGAGACGTTATACGAATCGTTGCTGGCGGCGC
AATATCGTTACGGCGCGGGTAAAAACTGTATTGAGGACATTAACTTTACGCCGGATACGTATCGTAAGTTACTGACCAAG
ACGCTTTTTGTTGGCCGGATTCTGGAAAAGTACAGCGTTGAGGGCGAGAAAATCGGTTTAATGCTGCCGAATGCCGCCAT
CAGCGCGGCGGTGATTTTCGGCGCGGTTTCTCGTCGCCGCATTCCGGCCATGATGAACTACACGGCGGGGGTAAAAGGGC
TGACCAGCGCGATTACCGCGGCGGAAATTAAAACGATTTTTACCTCCCGCCAGTTCCTCGATAAAGGTAAATTGTGGCAC
CTGCCGGAACAGCTAACGCAGGTTCGCTGGGTTTACCTGGAAGATTTAAAAGCGGACGTCACACCCGCCGACAAGCTGTG
GATTTTTGCCCACCTCCTGGCGCCGCGACTGGCGCAGGTAAAACAGCAGCCGGAAGACGCGGCGATCATTCTTTTTACCT
CCGGCTCGGAAGGGCACCCGAAAGGGGTGGTGCACAGCCATAAAAGCATTCTGGCGAACGTCGAGCAGATAAAAACGATT
GCGGATTTCACCGCCAATGACCGTTTTATGTCGGCGCTGCCGCTCTTTCACTCGTTCGGTTTGACGGTGGGCCTGTTTAC
GCCGTTGTTGACCGGCGCGGAAGTATTTCTTTATCCAAGTCCGCTGCACTATCGCATTGTGCCGGAACTGGTCTATGACC
GTAACTGTACCGTGCTGTTTGGTACGTCAACCTTCCTCGGCAACTATGCGCGCTTTGCCAATCCGTATGATTTTTATCGC
CTGCGCTATGTGGTGGCCGGTGCGGAAAAACTTCAGGAGAGCACCAAACAACTGTGGCAGGATAAATTCGGTCTGCGCAT
TCTTGAGGGCTACGGGGTAACGGAATGCGCGCCAGTAGTCTCGATTAACGTGCCGATGGCGGCTAAGCCTGGCACTGTTG
GCCGCATTCTGCCTGGCATGGACGCGCGTCTGCTGGCGGTGCCCGGTATTGAAAACGGCGGTCGGCTACAGCTGAAAGGG
CCGAATATCATGAATGGCTATCTGCGCGTGGAAAAACCGGGCGTGCTGGAGGTGCCGTCGGCGGAAAACTCCAGAGGCGA
AACTGAGCGCGGCTGGTACGACACGGGCGATATTGTACGCTTCGATGAAAATGGTTTTGTGCAGATTCAGGGGCGCGCGA
AACGCTTTGCGAAAATTGCTGGCGAAATGGTCTCGCTGGAGATGGTCGAGCAACTGGCGCTTGGCGTTTCGGCGGACAAA
ATGCACGCTACCGCCATTAAAAGCGATGCCAGCAAAGGTGAAGCGCTGGTACTGTTTACGACTGACAGCGAACTCACCCG
AGAAAAGTTACAGCACTATGCTCGTGAACACGGTATTCCGGAACTTGCCGTCCCGCGTGATATCCGTTATCTGAAGCAGC
TTCCCTTGCTTGGCAGCGGGAAACCCGATTTTGTGACGCTGAAAAGTTGGGTGGATGCGCCGGAACAACATCATGAGTGA

Upstream 100 bases:

>100_bases
GGTTTTTTTTCGAACCTATTTTGCTATCGCTCCTGTTACGCAACTCGTGTAATCTGCCACAATTCATCTTTTAGCGAATT
GTCGGCCAAAGGGAGTTGAA

Downstream 100 bases:

>100_bases
GTCAGTACGTACTAACACCTCCATCTGGTCGAAAGGGATGCTGTCGGTGATTGTCGCGCAGTTTCTCTCGGCTTTTGGCG
ATAATGCGCTGCTGTTCGCG

Product: bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase

Products: NA

Alternate protein names: 2-acylglycerophosphoethanolamine acyltransferase; 2-acyl-GPE acyltransferase; Acyl-[acyl-carrier-protein]--phospholipid O-acyltransferase; Acyl-[acyl-carrier-protein] synthetase; Acyl-ACP synthetase; Long-chain-fatty-acid--[acyl-carrier-protein] ligase [H]

Number of amino acids: Translated: 719; Mature: 719

Protein sequence:

>719_residues
MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLD
PTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRI
QLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTK
TLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWH
LPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTI
ADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYR
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKG
PNIMNGYLRVEKPGVLEVPSAENSRGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADK
MHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE

Sequences:

>Translated_719_residues
MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLD
PTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRI
QLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTK
TLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWH
LPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTI
ADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYR
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKG
PNIMNGYLRVEKPGVLEVPSAENSRGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADK
MHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
>Mature_719_residues
MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLD
PTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRI
QLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTK
TLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWH
LPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTI
ADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYR
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKG
PNIMNGYLRVEKPGVLEVPSAENSRGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADK
MHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE

Specific function: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=386, Percent_Identity=27.720207253886, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI187761343, Length=386, Percent_Identity=27.720207253886, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI40807491, Length=411, Percent_Identity=25.3041362530414, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI156151445, Length=355, Percent_Identity=26.1971830985915, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI42544132, Length=365, Percent_Identity=25.7534246575342, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI58082049, Length=366, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1789201, Length=719, Percent_Identity=91.6550764951321, Blast_Score=1369, Evalue=0.0,
Organism=Escherichia coli, GI1788107, Length=486, Percent_Identity=27.1604938271605, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI145693145, Length=358, Percent_Identity=29.608938547486, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1786810, Length=359, Percent_Identity=22.8412256267409, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17558820, Length=345, Percent_Identity=28.4057971014493, Blast_Score=125, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32563687, Length=340, Percent_Identity=27.9411764705882, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994690, Length=442, Percent_Identity=26.2443438914027, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994703, Length=442, Percent_Identity=26.2443438914027, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994694, Length=442, Percent_Identity=26.2443438914027, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17510401, Length=333, Percent_Identity=25.5255255255255, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=399, Percent_Identity=24.3107769423559, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17531443, Length=399, Percent_Identity=24.3107769423559, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541856, Length=407, Percent_Identity=25.5528255528256, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=364, Percent_Identity=22.8021978021978, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71985884, Length=282, Percent_Identity=23.758865248227, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319699, Length=361, Percent_Identity=26.0387811634349, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320852, Length=160, Percent_Identity=26.875, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355181, Length=479, Percent_Identity=24.0083507306889, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859661, Length=318, Percent_Identity=26.1006289308176, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24581924, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648260, Length=394, Percent_Identity=24.6192893401015, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922652, Length=316, Percent_Identity=25, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF01553 Acyltransferase; PF00501 AMP-binding [H]

EC number: =2.3.1.40; =6.2.1.20 [H]

Molecular weight: Translated: 80510; Mature: 80510

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTS
CCHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCEEEEECC
AGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARD
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHH
RRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
TLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITA
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHH
AEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQV
HHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
KQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFG
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
LTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYR
HHHHHHHHHHCCCEEEEECCCCCEEEEHHHHCCCCCEEEEECHHHHHCHHHHCCCHHHHH
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGM
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
DARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENSRGETERGWYDTGDIVR
CCEEEEECCCCCCCEEEECCCCEEECEEEECCCCEEECCCCCCCCCCCCCCCCCCCCEEE
FDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDASKGEALVLFT
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEE
TDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHHHCCCHHCCC
>Mature Secondary Structure
MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLITPNHVSFIDGMLLALFLPVRPVFAVYTS
CCHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEECCCEEEEECC
AGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARD
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHH
RRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTK
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
TLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITA
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHH
AEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQV
HHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
KQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFG
HCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHC
LTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYR
HHHHHHHHHHCCCEEEEECCCCCEEEEHHHHCCCCCEEEEECHHHHHCHHHHCCCHHHHH
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGM
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCC
DARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENSRGETERGWYDTGDIVR
CCEEEEECCCCCCCEEEECCCCEEECEEEECCCCEEECCCCCCCCCCCCCCCCCCCCEEE
FDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSADKMHATAIKSDASKGEALVLFT
ECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEE
TDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA