Click here to switch to the map view.

The map label for this gene is invF

Identifier: 16766205

GI number: 16766205

Start: 3043282

End: 3043932

Strand: Reverse

Name: invF

Synonym: STM2899

Alternate gene names: 16766205

Gene position: 3043932-3043282 (Counterclockwise)

Preceding gene: 16766209

Following gene: 16766204

Centisome position: 62.67

GC content: 45.93

Gene sequence:

>651_bases
ATGTCATTTTCTGAAAGCCGACACAATGAAAATTGCCTGATTCAGGAAGGCGCGCTGCTTTTTTGCGAGCAGGCCGTTGT
CGCACCAGTATCAGGAGACCTGGTTTTTCGACCGTTAAAAATTGAAGTACTCAGCAAATTACTGGCATTTATCGATGGCG
CAGGATTAGTGGACACGACATATGCTGAATCCGATAAATGGGTTTTGCTGAGTCCTGAGTTTCGCGCTATTTGGCAAGAT
CGTAAACGCTGCGAGTACTGGTTTTTGCAGCAAATTATTACGCCTTCTCCGGCCTTCAATAAGGTACTGGCGCTGTTACG
AAAAAGCGAGAGTTACTGGTTGGTTGGCTATTTACTCGCTCAGTCAACCAGCGGCAACACGATGAGAATGCTGGGAGAAG
ACTATGGCGTTTCTTATACCCATTTTCGTCGTTTGTGCAGCAGAGCGTTGGGCGGAAAAGCGAAGAGTGAATTACGAAAC
TGGCGTATGGCGCAATCGCTGCTGAATAGTGTAGAAGGCCACGAGAACATCACCCAATTAGCCGTTAATCATGGTTACTC
ATCGCCTTCACATTTTTCTAGTGAGATCAAAGAGCTGATCGGCGTTTCGCCGCGGAAATTATCAAATATTATTCAATTGG
CAGACAAATGA

Upstream 100 bases:

>100_bases
TATGCTAAATACGCAGGAAGTACTTAAAGAAGGAGAGAAGCGGAAAATCCGCAGCCCGGAAGCATGGTTTATACAGACGT
GTTCCGCGCAAAAGCTGCAT

Downstream 100 bases:

>100_bases
AGACACATATTCTTTTGGCCAGAGTGCTGGCATGTGCCGCGCTTGTTCTGGTTACACCTGGTTATTCTAGTGAAAAAATA
CCTGTAACGGGAAGTGGGTT

Product: invasion regulatory protein

Products: NA

Alternate protein names: Transcriptional regulator invF

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQD
RKRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRN
WRMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK

Sequences:

>Translated_216_residues
MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQD
RKRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRN
WRMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK
>Mature_215_residues
SFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQDR
KRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRNW
RMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK

Specific function: Transcriptional regulator required for the expression of several genes encoding type III secretion system SPI1 effector proteins. The interaction with sicA is necessary for the activation of sigDE (sopB pipC), sicAsipBCDA, and sopE

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): INVF_SALTI (P69342)

Other databases:

- EMBL:   AL627276
- EMBL:   AE014613
- RefSeq:   NP_457293.1
- RefSeq:   NP_806502.1
- ProteinModelPortal:   P69342
- SMR:   P69342
- PRIDE:   P69342
- GeneID:   1068843
- GeneID:   1249328
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2801
- KEGG:   sty:STY3022
- HOGENOM:   HBG391031
- OMA:   SEGRHNE
- ProtClustDB:   PRK15340
- BioCyc:   SENT209261:T2801-MONOMER
- BioCyc:   SENT220341:STY3022-MONOMER
- GO:   GO:0009405
- GO:   GO:0006350
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- SMART:   SM00342

Pfam domain/function: SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 24389; Mature: 24258

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTT
CCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCCCCCEECC
YAESDKWVLLSPEFRAIWQDRKRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLA
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHH
QSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRNWRMAQSLLNSVEGHENITQL
HCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRPLKIEVLSKLLAFIDGAGLVDTT
CCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCCCCCEECC
YAESDKWVLLSPEFRAIWQDRKRCEYWFLQQIITPSPAFNKVLALLRKSESYWLVGYLLA
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHH
QSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRNWRMAQSLLNSVEGHENITQL
HCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK
HHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504