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The map label for this gene is stpA

Identifier: 16766110

GI number: 16766110

Start: 2947225

End: 2947626

Strand: Reverse

Name: stpA

Synonym: STM2799

Alternate gene names: 16766110

Gene position: 2947626-2947225 (Counterclockwise)

Preceding gene: 16766112

Following gene: 16766107

Centisome position: 60.68

GC content: 46.52

Gene sequence:

>402_bases
ATGAATTTGATGTTACAGAACTTAAATAATATCCGCACGCTGCGCGCTATGGCTCGCGAATTCTCCATTGACGTTCTTGA
AGAAATGCTCGAAAAATTCAGGGTTGTCACTAAAGAAAGACGCGAAGAAGAAGAATTGCAGCAACGCCAGCTTGCCGAGA
AGCAGGAGAAAATTAATGCCTTTCTGGAGCTGATGAAAGCAGACGGTATTAACCCGGAAGAGTTATTTGCCATGGATTCA
GCAATGCCGCGTTCTGCTAAAAAGCGCCAGCCGCGTCCGGCAAAATATCGTTTTACTGATTTCAATGGCGAAGAAAAAAC
CTGGACCGGACAAGGTCGTACGCCTAAACCGATTGCCCAGGCGCTGGCGGCGGGGAAATCTCTGGATGATTTCTTAATCT
AA

Upstream 100 bases:

>100_bases
TATCTGTATGAACTTTAGGATCTGGAAATATAATCAACAATCGCATACAATACCGCCTGTAATAGTTTTTTGTTTTCTGC
GTTAAAAGGTTTTTATTGAT

Downstream 100 bases:

>100_bases
TCACGGATAGCTTTTAACAGATGGCGCTTCGTTTCCTGTCTCTATTAACCGGGACTCAGGGAACGTTGCGCCATGCTCAT
TTTGATAAATCAGCACACGC

Product: DNA binding protein, nucleoid-associated

Products: NA

Alternate protein names: H-NS homolog stpA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLELMKADGINPEELFAMDS
AMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQALAAGKSLDDFLI

Sequences:

>Translated_133_residues
MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLELMKADGINPEELFAMDS
AMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQALAAGKSLDDFLI
>Mature_133_residues
MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLELMKADGINPEELFAMDS
AMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQALAAGKSLDDFLI

Specific function: It may act in a fashion similar to H-NS proteins

COG id: COG2916

COG function: function code R; DNA-binding protein H-NS

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone-like protein H-NS family

Homologues:

Organism=Escherichia coli, GI1789023, Length=134, Percent_Identity=84.3283582089552, Blast_Score=206, Evalue=3e-55,
Organism=Escherichia coli, GI1787489, Length=135, Percent_Identity=54.0740740740741, Blast_Score=119, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): STPA_SALTI (P0A1S5)

Other databases:

- EMBL:   AL627276
- EMBL:   AE014613
- RefSeq:   NP_457198.1
- RefSeq:   NP_806403.1
- ProteinModelPortal:   P0A1S5
- PRIDE:   P0A1S5
- GeneID:   1069069
- GeneID:   1249231
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2695
- KEGG:   sty:STY2920
- HOGENOM:   HBG740436
- OMA:   NTWLELM
- ProtClustDB:   PRK10328
- BioCyc:   SENT209261:T2695-MONOMER
- BioCyc:   SENT220341:STY2920-MONOMER
- GO:   GO:0005622
- InterPro:   IPR001801
- SMART:   SM00528

Pfam domain/function: PF00816 Histone_HNS

EC number: NA

Molecular weight: Translated: 15488; Mature: 15488

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLELMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQ
HHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCCCEECCCCCCCHHHHH
ALAAGKSLDDFLI
HHHCCCCHHHHCC
>Mature Secondary Structure
MNLMLQNLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLELMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQ
HHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCCCEECCCCCCCHHHHH
ALAAGKSLDDFLI
HHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504