Click here to switch to the map view.

The map label for this gene is nagD [H]

Identifier: 16764051

GI number: 16764051

Start: 740893

End: 741645

Strand: Reverse

Name: nagD [H]

Synonym: STM0681

Alternate gene names: 16764051

Gene position: 741645-740893 (Counterclockwise)

Preceding gene: 16764052

Following gene: 16764050

Centisome position: 15.27

GC content: 54.32

Gene sequence:

>753_bases
ATGACCATCAAGAATGTAATCTGCGATATCGACGGCGTGCTGATGCACGACAACGTAGCCGTACCCGGTGCGGCGGAATT
TCTGACGGGGATTCTGGAAAAAGGTCTGCCGCTGGTGCTGCTGACCAATTACCCATCGCAAACCGGCCAGGATCTGGCGA
ACCGTTTTGCTACCGCTGGCGTTAACGTGCCGGACAGCGTGTTTTATACGTCAGCAATGGCGACAGCCGATTTTCTGCGC
CGTCAGGAAGGTAAAAAAGCGTATGTCGTGGGCGAAGGCGCGCTTATTCACGAGCTCTATAAAGCGGGTTTTACCATTAC
CGATGTGAACCCTGATTTTGTCATCGTTGGAGAAACCCGCTCCTACAACTGGGACATGATGCATAAAGCAGCATTTTTCG
TCGCCAATGGCGCGCGCTTTATCGCCACCAACCCGGATACCCACGGTCGCGGCTTTTATCCGGCCTGCGGCGCGCTGTGC
GCAGGCATTGAAAAAATTTCCGGCCGGAAGCCATTTTATGTCGGCAAACCCAGCCCGTGGATCATCCGCGCGGCGTTAAA
CAAAATGCAGGCGCACTCGGAAGAGACCGTTATTGTCGGCGATAACCTGCGCACCGACATTCTGGCGGGGTTCCAGGCCG
GTCTGGAGACCATTCTGGTGCTTTCAGGCGTATCAACGATCAATGATATTGACAGTATGCCGTTCCGCCCAAGCTGGATT
TACCCTTCCGTCGCCGAGATAGACGTTATCTAA

Upstream 100 bases:

>100_bases
GTTAAACGCGCCATGCTCAACGGAACATTGCTGCAATGTTTGCTGGAAAGTTGATGCGCTCTTATAGTATCGGATTATTC
ACAAATTCCCTGGGTAGTTC

Downstream 100 bases:

>100_bases
ACCTGTCCTCTGCCTGATGACGCATAGCTTTCAGGCCTACGGTTCGAACAACATTGTAGGTCTGATAAGCGAAACGCCAT
CAGGAAAAACATAATTCAAT

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNYPSQTGQDLANRFATAGVNVPDSVFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSTINDIDSMPFRPSWI
YPSVAEIDVI

Sequences:

>Translated_250_residues
MTIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNYPSQTGQDLANRFATAGVNVPDSVFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSTINDIDSMPFRPSWI
YPSVAEIDVI
>Mature_249_residues
TIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNYPSQTGQDLANRFATAGVNVPDSVFYTSAMATADFLRR
QEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCA
GIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSTINDIDSMPFRPSWIY
PSVAEIDVI

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI108796653, Length=265, Percent_Identity=30.9433962264151, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI10092677, Length=252, Percent_Identity=28.968253968254, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI14149777, Length=247, Percent_Identity=25.1012145748988, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786890, Length=250, Percent_Identity=96.8, Blast_Score=505, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17560956, Length=263, Percent_Identity=27.7566539923954, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562458, Length=263, Percent_Identity=27.7566539923954, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=263, Percent_Identity=27.7566539923954, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71984613, Length=264, Percent_Identity=26.8939393939394, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562356, Length=233, Percent_Identity=24.0343347639485, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193210059, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319965, Length=234, Percent_Identity=26.4957264957265, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666141, Length=253, Percent_Identity=26.8774703557312, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24656326, Length=258, Percent_Identity=27.1317829457364, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI22026920, Length=243, Percent_Identity=29.6296296296296, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666137, Length=291, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656330, Length=275, Percent_Identity=26.9090909090909, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19920940, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27119; Mature: 26988

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNYPSQTGQDLANRFATAG
CCHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
VNVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCC
IIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSTINDIDSMPFRPSWI
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
YPSVAEIDVI
CCCCEEEECC
>Mature Secondary Structure 
TIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNYPSQTGQDLANRFATAG
CHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
VNVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALCAGIEKISGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCC
IIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSTINDIDSMPFRPSWI
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCC
YPSVAEIDVI
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]