Click here to switch to the map view.

The map label for this gene is nagC [H]

Identifier: 16764052

GI number: 16764052

Start: 741692

End: 742912

Strand: Reverse

Name: nagC [H]

Synonym: STM0682

Alternate gene names: 16764052

Gene position: 742912-741692 (Counterclockwise)

Preceding gene: 16764053

Following gene: 16764051

Centisome position: 15.29

GC content: 53.4

Gene sequence:

>1221_bases
ATGACACCAGGCGGACAAGCTCAGATAGGTAACGTTGATCTCGTAAAACAGCTTAACAGCGCGGCCGTTTACCGCCTGAT
TGACCAGCATGGTCCTATCTCGCGCATACAAATTGCCGAGCAAAGCCAGCTTGCTCCCGCCAGCGTAACGAAAATTACGC
GTCAACTCATTGAACGCGGGCTGATCAAAGAAGTCGATCAGCAGGCCTCTACCGGAGGCCGCCGCGCTATCTCTATCGTC
ACGGAAACCCGTAACTTCCACGCCATTGGCGTTCGCCTGGGGCGTCATGACACCACTTTAACGCTCTACGATCTGAGCAG
TAAAGTGGTCGCTGAGGAGCATTATCCGCTGCCGGAGCGCACCCAGGAGACGCTGGAACATGCGCTGCTCAACACTATCG
CCGTCTTTATTGATAGCTGTCAGCGTAAAATTCGTGAATTGATCGCTATCTCGGTGATCCTGCCAGGGCTTGTCGATCCG
GAAAGCGGCGTGATTCGTTACATGCCGCACATTCAGGTTGAAAACTGGGGACTGGTCGAAGCGCTGGAAAAACGGTTTCA
CGTTACCTGTTTCGTGGGACACGATATCCGTAGCCTGGCGCTGGCGGAACACTACTTCGGCGCCAGTCAGGATTGCGAGG
ACTCGATTCTGGTGCGCGTTCATCGTGGTACAGGCGCCGGGATTATCTCCAACGGACGCATCTTCATTGGCCGTAACGGC
AACGTCGGTGAAATTGGGCATATTCAGGTGGAGCCGCTGGGCGAGCGCTGCCACTGCGGTAATTTCGGCTGTCTGGAAAC
CATTGCCGCCAATGCGGCGATTGAACAACGGGTGCTGAATTTGCTTAAACAAGGGTATCAAAGCCGTGTTCCGCTTGACG
ACTGCACGATTAAAACCATCTGTAAGGCGGCAAACCGGGGCGACAGCCTGGCCTCGGAAGTCATTGAGCATGTTGGTCGC
CATTTGGGCAAAACGATCGCCATTGCTATCAACCTGTTTAATCCGCAAAAAATCGTCATTGCCGGCGAGATCATTGAAGC
CGATAAAGTCCTGTTACCCGCTATCGAAAGCTGTATCAATACGCAGGCGTTAAAGGCATTTCGCAAAAATTTGCCGGTGG
TACGCTCCACGCTGGATCACCGTTCTGCTATCGGCGCATTTGCCTTAGTTAAACGCGCCATGCTCAACGGAACATTGCTG
CAATGTTTGCTGGAAAGTTGA

Upstream 100 bases:

>100_bases
CCGGGTAAAGTCGCCAACCTGACCGCGTTCACCCACGATTTTAAAATTATCAAGACCATCGTTAATGGTGACGAGGTCGT
TGACTTGAGTAAGTGAGAAT

Downstream 100 bases:

>100_bases
TGCGCTCTTATAGTATCGGATTATTCACAAATTCCCTGGGTAGTTCATGACCATCAAGAATGTAATCTGCGATATCGACG
GCGTGCTGATGCACGACAAC

Product: N-acetylglucosamine operon transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQLAPASVTKITRQLIERGLIKEVDQQASTGGRRAISIV
TETRNFHAIGVRLGRHDTTLTLYDLSSKVVAEEHYPLPERTQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDP
ESGVIRYMPHIQVENWGLVEALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNG
NVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTICKAANRGDSLASEVIEHVGR
HLGKTIAIAINLFNPQKIVIAGEIIEADKVLLPAIESCINTQALKAFRKNLPVVRSTLDHRSAIGAFALVKRAMLNGTLL
QCLLES

Sequences:

>Translated_406_residues
MTPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQLAPASVTKITRQLIERGLIKEVDQQASTGGRRAISIV
TETRNFHAIGVRLGRHDTTLTLYDLSSKVVAEEHYPLPERTQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDP
ESGVIRYMPHIQVENWGLVEALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNG
NVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTICKAANRGDSLASEVIEHVGR
HLGKTIAIAINLFNPQKIVIAGEIIEADKVLLPAIESCINTQALKAFRKNLPVVRSTLDHRSAIGAFALVKRAMLNGTLL
QCLLES
>Mature_405_residues
TPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQLAPASVTKITRQLIERGLIKEVDQQASTGGRRAISIVT
ETRNFHAIGVRLGRHDTTLTLYDLSSKVVAEEHYPLPERTQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDPE
SGVIRYMPHIQVENWGLVEALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNGN
VGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTICKAANRGDSLASEVIEHVGRH
LGKTIAIAINLFNPQKIVIAGEIIEADKVLLPAIESCINTQALKAFRKNLPVVRSTLDHRSAIGAFALVKRAMLNGTLLQ
CLLES

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=406, Percent_Identity=94.3349753694581, Blast_Score=779, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=400, Percent_Identity=40.75, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI87082127, Length=347, Percent_Identity=23.6311239193084, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=23.1617647058824, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790522, Length=293, Percent_Identity=24.5733788395904, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44442; Mature: 44311

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQLAPASVTKITRQLIERG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHEEECHHCCCCHHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDTTLTLYDLSSKVVAEEHYPLPER
HHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEECCCHHHHHCCCCCCHH
TQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDPESGVIRYMPHIQVENWGLVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEECCCCHHH
ALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNG
HHHHCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEECCEEEEECCC
NVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
CKAANRGDSLASEVIEHVGRHLGKTIAIAINLFNPQKIVIAGEIIEADKVLLPAIESCIN
HHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHC
TQALKAFRKNLPVVRSTLDHRSAIGAFALVKRAMLNGTLLQCLLES
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQLAPASVTKITRQLIERG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHEEECHHCCCCHHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDTTLTLYDLSSKVVAEEHYPLPER
HHHHHHHHHCCCCCEEEEEEEECCCEEEEEEEECCCCCEEEEEECCCHHHHHCCCCCCHH
TQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDPESGVIRYMPHIQVENWGLVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCEEECCCCHHH
ALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNG
HHHHCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEECCEEEEECCC
NVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
CKAANRGDSLASEVIEHVGRHLGKTIAIAINLFNPQKIVIAGEIIEADKVLLPAIESCIN
HHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHC
TQALKAFRKNLPVVRSTLDHRSAIGAFALVKRAMLNGTLLQCLLES
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]