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The map label for this gene is dmsB [H]

Identifier: 16763989

GI number: 16763989

Start: 675980

End: 676537

Strand: Direct

Name: dmsB [H]

Synonym: STM0612

Alternate gene names: 16763989

Gene position: 675980-676537 (Clockwise)

Preceding gene: 16763988

Following gene: 16763990

Centisome position: 13.92

GC content: 53.76

Gene sequence:

>558_bases
ATGAGACGTGCGTTTTTAGTGAATAGCGATAAGTGCATCGGCTGCCGCGGCTGTGCTATGGCGTGTAAAAGCTTTAACCA
ACTGGAGCCGGATCGCTTCTGGCGCTACGTTTATCCGTTGGATAAAGACATCTATCCACATGAAGAGCGGGCGTTTTACT
CGCTGGCCTGTAACCACTGCGAACATCCGGCCTGCGTCGCCGCCTGTCCGGTCGAAGCCTATACCAAACGTGAAGATGGC
GTGGTGGTGCATAACCCTGAGCGCTGCATCGGCTGTAAAAACTGTATTCGTAACTGTCCTTATGGCGCGCCGCGTTTTAA
TGAAGAGACGCGTAAAGCGGAAAAATGCAGTATGTGCTACGAGCGTCTTGATATCGGTATGAATCCGGCGTGCGTAAACG
CCTGTCCGGTGGGCGCCTTGTCGATTATCGATTTGGATGCCGATCCTGTGCCCGATAATGCGGTGCAGTATCCGCCAGGG
TTCCCGCATATGCCACAGCTTAATCCAGGAACGCGCTTTATTCTGGCGCGCCAGCCTAAGCAGCCGGAGGACAAGTAA

Upstream 100 bases:

>100_bases
CGCCTGCTGATATGGGGCTGATGAAAACTGGCGCGCCGGGCGCCGCTATCCACAGTCAGTTTGCTGACGTTGTATTGATC
GGTAAAGGGGAATCCGTAGC

Downstream 100 bases:

>100_bases
TGGAAAAATATGAACTGCCGCTGGTGTTTTTTACGGTATTAAGCCAGATGTCTGTCGGGATGGCTTTGGTACTGACATGG
CGTACGCTGCGTGGTGAAGT

Product: hydrogenase protein

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDIYPHEERAFYSLACNHCEHPACVAACPVEAYTKREDG
VVVHNPERCIGCKNCIRNCPYGAPRFNEETRKAEKCSMCYERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPG
FPHMPQLNPGTRFILARQPKQPEDK

Sequences:

>Translated_185_residues
MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDIYPHEERAFYSLACNHCEHPACVAACPVEAYTKREDG
VVVHNPERCIGCKNCIRNCPYGAPRFNEETRKAEKCSMCYERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPG
FPHMPQLNPGTRFILARQPKQPEDK
>Mature_185_residues
MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDIYPHEERAFYSLACNHCEHPACVAACPVEAYTKREDG
VVVHNPERCIGCKNCIRNCPYGAPRFNEETRKAEKCSMCYERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPG
FPHMPQLNPGTRFILARQPKQPEDK

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=151, Percent_Identity=41.0596026490066, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787872, Length=150, Percent_Identity=40.6666666666667, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1787749, Length=154, Percent_Identity=32.4675324675325, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790326, Length=154, Percent_Identity=32.4675324675325, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367345, Length=183, Percent_Identity=32.7868852459016, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI2367245, Length=155, Percent_Identity=34.8387096774194, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI226510944, Length=143, Percent_Identity=36.3636363636364, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI87082179, Length=153, Percent_Identity=37.2549019607843, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787740, Length=121, Percent_Identity=35.5371900826446, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1787478, Length=132, Percent_Identity=34.8484848484849, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1788811, Length=150, Percent_Identity=30, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1789370, Length=167, Percent_Identity=31.7365269461078, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787963, Length=155, Percent_Identity=27.0967741935484, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI87082180, Length=150, Percent_Identity=32.6666666666667, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1789067, Length=166, Percent_Identity=33.7349397590361, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 20903; Mature: 20903

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
11.4 %Cys+Met (Translated Protein)
8.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
11.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDIYPHEERAFYSLACNHC
CCCEEEECCCCEECHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCCCHHHHHHHHHHHCC
EHPACVAACPVEAYTKREDGVVVHNPERCIGCKNCIRNCPYGAPRFNEETRKAEKCSMCY
CCCCEEEECCHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPGFPHMPQLNPGTRFILARQPK
HHHHCCCCCHHHCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCC
QPEDK
CCCCC
>Mature Secondary Structure
MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDIYPHEERAFYSLACNHC
CCCEEEECCCCEECHHHHHHHHHHHCCCCHHHHEEEECCCCCCCCCCHHHHHHHHHHHCC
EHPACVAACPVEAYTKREDGVVVHNPERCIGCKNCIRNCPYGAPRFNEETRKAEKCSMCY
CCCCEEEECCHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPGFPHMPQLNPGTRFILARQPK
HHHHCCCCCHHHCCCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCEEEEECCCC
QPEDK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]