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The map label for this gene is ybdL [H]

Identifier: 16763980

GI number: 16763980

Start: 664891

End: 666051

Strand: Direct

Name: ybdL [H]

Synonym: STM0603

Alternate gene names: 16763980

Gene position: 664891-666051 (Clockwise)

Preceding gene: 16763978

Following gene: 16763985

Centisome position: 13.69

GC content: 54.26

Gene sequence:

>1161_bases
ATGAGAAATAACCCACTGATTCCAAAAAGCAAATTGCCAAATCTTGGTACCACGATTTTTACGCAAATGAGCGCGCTGGC
GCAGAAACATCAGGCAATAAATTTATCGCAAGGCTTCCCTGATTTTGATGGTCCTCGTTATTTGCACGAGCGGTTGGCTT
ATCATGTCGCGCAGGGCGCGAATCAATATGCGCCGATGACGGGGGCGCAGGCGCTGCGGGAGGCCATTGCCGATAAAACG
GCGGAAATATATGGTTATCGACCCGATGACGTCAGTGATATCACCGTCACAGCGGGCGCGACAGAAGCGCTGTATGCGGC
GATTACCGCGCTGGTGCGGGCAGGGGATGAGGTTATCTGTTTCGATCCCAGTTACGACAGCTATGCCCCAGCCGTGGCGC
TCTCCGGCGGCGTGTTAAAACGCATAGCGCTTACGCCGCCGCATTTTCGCGTCGACTGGCAGGCGTTTTCGGCGTTGCTT
AGCGAGCGCACGCGACTGGTGATCCTCAATACGCCGCATAATCCCACCGCTACCGTCTGGCGTCAGGCGGATATCGAGGC
GCTGTGGCAGGCTATCGGCGAGCGGGAAATTTATGTGTTAAGCGATGAAGTGTACGAACATATTTGTTTTGCCGCCGAAG
GTCATGCCAGCGTATTGGCGCACCCTCAGTTACGAGAGCGGGCGGTTGCCGTTTCATCGTTTGGTAAAACCTTTCATATG
ACAGGATGGAAGATTGGTTACTGCGTTGCGCCTGCGGCCATTAGCGCCGAAATACGCAAAGTTCATCAGTACCTGACGTT
TTGCGTCAATACGCCGGCGCAACTGGCGCTGGCGGATATGCTGCGCGCCGCGCCGGAACACTATCGCGCGTTACCCGATT
TTTACCGGAAAAAACGCGATGTGCTGGTTAACGCGCTGGCGCAAAGCCGATTAAAAGTGCTGCCCTGTGAAGGTACCTAT
TTTCTGTTAATCGATTACAGCGCAGTGTCGACGCTAAATGACGTTGAGTTTTGTCAGTGGCTAACCGAAGAAGTCGGTGT
CGCCGCTATTCCGCTCTCTGTCTTTTGCGCCGCCCCTTTCCCGCATCAGCTTATACGTTTATGTTTCGCTAAACAGGAAT
CAACGCTGCTGGCCGCCGCAGAGCGCCTGTGTAAACTGTAG

Upstream 100 bases:

>100_bases
CCGTTGTTATTATATTTAGACATCTAAACGTCTTGATTGCCAAATACTAACACCCTGTGATAGTGTGTCAACAACCACAT
CACTGGCGGGTATGAAGATA

Downstream 100 bases:

>100_bases
TTATTTAACCGTCCACGCTCTGGAGAATCGACGGTCTGCAAAAAGCTCCTGCAGGCCGTTGATCTGTTTCAGGCGCAGGA
CTTCATCGGCGTCCATACCT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPRYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL

Sequences:

>Translated_386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPRYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL
>Mature_386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPRYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=410, Percent_Identity=30.7317073170732, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI169881279, Length=410, Percent_Identity=30.7317073170732, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=31.9201995012469, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=31.9201995012469, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI169881281, Length=410, Percent_Identity=26.8292682926829, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4507369, Length=338, Percent_Identity=23.9644970414201, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=85.4922279792746, Blast_Score=696, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=25.5192878338279, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788627, Length=308, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=413, Percent_Identity=30.5084745762712, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI71994472, Length=413, Percent_Identity=30.5084745762712, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17567369, Length=404, Percent_Identity=27.7227722772277, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17567663, Length=346, Percent_Identity=23.121387283237, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=29.5918367346939, Blast_Score=176, Evalue=6e-45,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI18859735, Length=313, Percent_Identity=27.1565495207668, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42680; Mature: 42680

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPRYLHERLAYHVAQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
NQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVIC
CCCCCCHHHHHHHHHHHHCHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
FDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALLSERTRLVILNTPHNPTATVW
ECCCCCCCCCHHHHCCHHHHHHCCCCCCCEECHHHHHHHHHCCCEEEEEECCCCCCHHHH
RQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHCCCEEEE
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRD
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPF
HHHHHHHHCCEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCC
PHQLIRLCFAKQESTLLAAAERLCKL
HHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPRYLHERLAYHVAQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
NQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVIC
CCCCCCHHHHHHHHHHHHCHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
FDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALLSERTRLVILNTPHNPTATVW
ECCCCCCCCCHHHHCCHHHHHHCCCCCCCEECHHHHHHHHHCCCEEEEEECCCCCCHHHH
RQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHCCCEEEE
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRD
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPF
HHHHHHHHCCEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCC
PHQLIRLCFAKQESTLLAAAERLCKL
HHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]