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The map label for this gene is manX [C]

Identifier: 16763954

GI number: 16763954

Start: 636379

End: 636828

Strand: Reverse

Name: manX [C]

Synonym: STM0577

Alternate gene names: 16763954

Gene position: 636828-636379 (Counterclockwise)

Preceding gene: 16763955

Following gene: 16763953

Centisome position: 13.11

GC content: 52.22

Gene sequence:

>450_bases
GTGAGACATGTTTATGTAGCCAGCCATGGCCCTTTTGCCCGCGGACTTATTAACAGTCTATCGCTGCTGATTGGCGACGA
ACACGGCGTGACACCGGTTTGCGCCTACGATGGCGATATTGTCACCACGGAGCAGCTTGAACAAACCCTCGAAAATCTGA
TCGCGCAAGCCAACGGCGAAGAAGTGGTGGTGTTTACCGATCTGCTCGGCGGCAGCATCAACAATAGCGCCGCGAAAGTG
CTGATGCGTCACCGTCACGTTTTTGTGGTGGCTGGCGTCAACATGACCCTGTTGCTGGAGTTTTTACTCTGTGAAGAAGA
AAGCACAGACGCGGCCATTACCTACGCCACCAATGCGGCGCGTGAATCCATTGTCTTTATCAACACGCTAATAACACAAC
CATCCGCTGACCTACAGGGAGAATCCCATGATCAAATTAGTGCGCATTGA

Upstream 100 bases:

>100_bases
TTAACTTCCTCTTTCAATTTATTGAAAATAAATAACATTTAAAACTGGCACGCCGTTTGCCATATCTGGATACCCCCTAT
CTGGATGAAGGAGAAAACGG

Downstream 100 bases:

>100_bases
TTACCGCCTGCTGCACGGCCAGGTGGTCTTCGCCTGGACCCGGGCGCTGGATATCGACCATATCATCGTCGCTAACGCCA
ACGCCGCCGGCGACGCGTTT

Product: PTS system mannose-specific enzyme IIAB

Products: protein histidine; sugar phosphate

Alternate protein names: PTS System Fructocific IIA Component; PTS System Mannose-Specific IIA Component; PTS System Mannose-Specific Transporter Subunit IIAB

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRHVYVASHGPFARGLINSLSLLIGDEHGVTPVCAYDGDIVTTEQLEQTLENLIAQANGEEVVVFTDLLGGSINNSAAKV
LMRHRHVFVVAGVNMTLLLEFLLCEEESTDAAITYATNAARESIVFINTLITQPSADLQGESHDQISAH

Sequences:

>Translated_149_residues
MRHVYVASHGPFARGLINSLSLLIGDEHGVTPVCAYDGDIVTTEQLEQTLENLIAQANGEEVVVFTDLLGGSINNSAAKV
LMRHRHVFVVAGVNMTLLLEFLLCEEESTDAAITYATNAARESIVFINTLITQPSADLQGESHDQISAH
>Mature_149_residues
MRHVYVASHGPFARGLINSLSLLIGDEHGVTPVCAYDGDIVTTEQLEQTLENLIAQANGEEVVVFTDLLGGSINNSAAKV
LMRHRHVFVVAGVNMTLLLEFLLCEEESTDAAITYATNAARESIVFINTLITQPSADLQGESHDQISAH

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 16103; Mature: 16103

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVYVASHGPFARGLINSLSLLIGDEHGVTPVCAYDGDIVTTEQLEQTLENLIAQANGE
CCEEEEECCCCHHHHHHHHHHHEECCCCCCCEEEECCCCEECHHHHHHHHHHHHHHCCCC
EVVVFTDLLGGSINNSAAKVLMRHRHVFVVAGVNMTLLLEFLLCEEESTDAAITYATNAA
EEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
RESIVFINTLITQPSADLQGESHDQISAH
CCCEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHVYVASHGPFARGLINSLSLLIGDEHGVTPVCAYDGDIVTTEQLEQTLENLIAQANGE
CCEEEEECCCCHHHHHHHHHHHEECCCCCCCEEEECCCCEECHHHHHHHHHHHHHHCCCC
EVVVFTDLLGGSINNSAAKVLMRHRHVFVVAGVNMTLLLEFLLCEEESTDAAITYATNAA
EEEEEEECCCCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
RESIVFINTLITQPSADLQGESHDQISAH
CCCEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA