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The map label for this gene is treB [H]

Identifier: 218930704

GI number: 218930704

Start: 4131221

End: 4132636

Strand: Reverse

Name: treB [H]

Synonym: YPO3697

Alternate gene names: 218930704

Gene position: 4132636-4131221 (Counterclockwise)

Preceding gene: 218930705

Following gene: 218930703

Centisome position: 88.8

GC content: 51.55

Gene sequence:

>1416_bases
ATGGGCAAAGTAAAACAGCAGGATATCGATCAACTGATCGTTCTGGTGGGAGGCAGAGAAAATATTGCCACCGTCAGTCA
CTGCATTACTCGATTACGTTTTGTATTAAAAGATCCGTCGATAGCATCACCAAAAGAGATTGAAAATCTCTCAATGGTCA
AAGGCTGTTTTACTAATGCAGGCCAATTTCAAGTGGTCATCGGGCCAGAAGTCGATGATTACTATAAAGCATTGATTGCT
AAGATTGGCCAAAGTGAAGTGGACAAAGAACAGACCAAGCTCGCGGCACGGCAGAACATGACTTGGTTTGAGCGCGGTAT
TTCTCACTTTGCTGAGATCTTCTTCCCGTTGCTACCGGCGCTGATCAGCGGAGGGTTAATCCTCGGCTTCCGTAATGTCA
TCGGTGACATCCCAATGTCTGAGGGGAAAACGCTGGCGCAGATGTACCCCGCGTGGCAAACCATTTATGACTTCCTCTGG
TTACTTGGCGAAGCCATCTTCTTCTACTTGCCTGTCGCGATCTGCTGGTCAACAGTGAAGAAAATGGGCGGGACCCCGGT
ATTGGGGATTGTACTGGGGATCACACTGGTCTCTCCGCAATTGATGAACTCCTACTTACTGGGGCAACAACTGCCTGACG
TCTGGAACTTCGGTTGGTTTACCATTGAAAAAGTGGGTTATCAGGCACAGGTGATCCCCTCTATTTTGGCGGGTCTGGCG
CTGGGGTGGATTGAAACCAACTTGAAGAGAATCATCCCCGCCTATCTCTACCTGGTGGTCGTCCCTGTGGTCTCCCTGCT
GCTAGCCGTGTTCCTGGCCCATACACTGATTGGGCCGTTTGGCCGCATGATTGGTGACGGTGTGGCATGGGGCGTGAAGG
CGGTGATGACCGGCAGTTTCGCACCGGTCGGTGCGGCACTATTTGGTTTCCTGTATGCACCGCTGGTGATTACTGGGGTA
CATCAGACCACGCTGGCTATTGATATGCAGATGGTTCAGAGCATGGGCGGCACACCGGTCTGGCCATTGATTGCGTTGTC
CAACATCGCACAAGCTTCGGCGGTACTGGGTATCATCATCATCAGCCGTAAAATCAATGAACGTGAGATTTCAGTACCCG
CAGCGATCTCCGCCTATCTGGGCGTGACCGAACCAGCAATGTACGGTATCAATCTGAAATACCGTTTCCCGATGTTATGC
GCCATGATCGGTTCCGCACTGGCTGGCCTGATTTGTGGGTTGACGGGAGTCATGGCGAACGGCATCGGTGTGGGTGGGTT
GCCCGGTATTTTATCTATCCAACCGCAGTTCTGGGGAATTTATGCCGTGGCGATGTTAGTGGCCATCGTGGTGCCATTAG
CACTGACCATTCTGGTGTATAAGCGTAAAGAGCGTCGTGGCGAATTGCCAGTCTGA

Upstream 100 bases:

>100_bases
ACACCGAGTAAAAAGGGAATTATAGATTTAATTCGCTGCTGACTTCAGGCAGAGATGGCATCTCATGCGCGCACGTAACC
TTTACGGAAAGGACGATAAA

Downstream 100 bases:

>100_bases
AGGGTGTCGATCTGGATGATGTCGATATAAGTTGTGTTCTCCCGCCAGCGGTGATCGTCTGGCGGGGTCATTTTTCAATG
AATAAGAGTCCGCTATGAAT

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIGPEVDDYYKALIA
KIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLW
LLGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQAQVIPSILAGLA
LGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALFGFLYAPLVITGV
HQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGELPV

Sequences:

>Translated_471_residues
MGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIGPEVDDYYKALIA
KIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLW
LLGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQAQVIPSILAGLA
LGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALFGFLYAPLVITGV
HQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGELPV
>Mature_470_residues
GKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNAGQFQVVIGPEVDDYYKALIAK
IGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLWL
LGEAIFFYLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQAQVIPSILAGLAL
GWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSFAPVGAALFGFLYAPLVITGVH
QTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIIIISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCA
MIGSALAGLICGLTGVMANGIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGELPV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=471, Percent_Identity=80.4670912951168, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=408, Percent_Identity=26.9607843137255, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788769, Length=427, Percent_Identity=26.6978922716628, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI48994906, Length=425, Percent_Identity=25.1764705882353, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51015; Mature: 50883

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNA
CCCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
GQFQVVIGPEVDDYYKALIAKIGQSEVDKEQTKLAARQNMTWFERGISHFAEIFFPLLPA
CCEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LISGGLILGFRNVIGDIPMSEGKTLAQMYPAWQTIYDFLWLLGEAIFFYLPVAICWSTVK
HHCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGGTPVLGIVLGITLVSPQLMNSYLLGQQLPDVWNFGWFTIEKVGYQAQVIPSILAGLA
HCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHCCCCEEHHHHCCHHHHHHHHHHHHH
LGWIETNLKRIIPAYLYLVVVPVVSLLLAVFLAHTLIGPFGRMIGDGVAWGVKAVMTGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
APVGAALFGFLYAPLVITGVHQTTLAIDMQMVQSMGGTPVWPLIALSNIAQASAVLGIII
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ISRKINEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCAMIGSALAGLICGLTGVMAN
HHCCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGVGGLPGILSIQPQFWGIYAVAMLVAIVVPLALTILVYKRKERRGELPV
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GKVKQQDIDQLIVLVGGRENIATVSHCITRLRFVLKDPSIASPKEIENLSMVKGCFTNA
CCCCHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCC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CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]