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The map label for this gene is treR [H]

Identifier: 218930705

GI number: 218930705

Start: 4133047

End: 4134000

Strand: Reverse

Name: treR [H]

Synonym: YPO3698

Alternate gene names: 218930705

Gene position: 4134000-4133047 (Counterclockwise)

Preceding gene: 218930706

Following gene: 218930704

Centisome position: 88.83

GC content: 51.05

Gene sequence:

>954_bases
ATGCAAAACCGTTTGACCATTAAAGATATTGCCCGCATGAGTGGTGTTGGAAAATCCACAGTTTCACGGGTATTAAATAA
TGAAGGCAGCGTCAGCCCACAGACCCGTGAACGGGTCGAGGCGGTGATCCGCCAGCACGGTTTTACCCCCTCCAAATCGG
CCCGAGCCATGCGTGGGCAAAGCGACAAAGTTGTTGGCATCATTGTCTCTCGTCTCGATTCGCCATCCGAGAACCAGGCA
GTACGTACTATGTTACCGCTGTTCTATCAACAAGGTTACGACCCGATCCTGATGGAGAGCCAATTTGATACCACATTGGT
TAGCGAGCATTTACATATTCTGCAACAACGCCATGTTGATGGCGTGATCCTGTTCGGTTTCAGCGGATTAACTGCAGAAA
TGCTGGCACCGTGGCAGGAAAAAATGGTGGTGCTGGCGCGCGAGTACCGTGGTTTTTCTTCTGTCTGCTATGACGATGAA
GGTGCCATATACCTCTTGATGGACAAATTACGCCAAGCCGGGCACCGCCATATCAGTTATATCGGCGTACAATCTTCCGA
TGCAACCACCGGTATGCGCCGCTATCAAGCCTATCTCGATTACAGTCAACAGCATGGCCTGACACCCATGGTGGCGCTGG
GGGAGTTGAGCTATCAGAGTGGCTTTCAGCTCGCTCCTCAGGTGATAACCCCACAAACCTCGGCATTGGTTTGTGCCTCT
GACACTATCGCCATGGGCGTCAGTAAATACTTGCAACAGCAGGAGCGGGAGCAGCCCCCCATTCAGGTATGCGGTATTGG
TAATACACCGCTGTTACACTTTTTGTTTCCCGATACCTTAACCATTGAGCTGGGTTATGGCCGTGCAGGTGTGAAAGCCG
CGCAGCAATTACTGGACCAACTGAGTAATAGCCAACCTATTCAGCAAATTATTATTCCGGGCCAACTCGTCTGA

Upstream 100 bases:

>100_bases
GCGTGCCATCTGGTTCTATGCATCTCGAACTTCCCAATACCACTGCATATATAAATAATGAGTTTAAAATGTATTTTCAA
ACCTGAACATTAGGCAAACC

Downstream 100 bases:

>100_bases
TCCCATCCTGTACAGAGGAATAACGCTGCATCGATGGCCTTAACAGTGAACAACTGTATAAAAATTTATCAATTTGTGAT
CTTCAATACAAAATGGGAAC

Product: trehalose repressor

Products: NA

Alternate protein names: Trehalose operon repressor [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQNRLTIKDIARMSGVGKSTVSRVLNNEGSVSPQTRERVEAVIRQHGFTPSKSARAMRGQSDKVVGIIVSRLDSPSENQA
VRTMLPLFYQQGYDPILMESQFDTTLVSEHLHILQQRHVDGVILFGFSGLTAEMLAPWQEKMVVLAREYRGFSSVCYDDE
GAIYLLMDKLRQAGHRHISYIGVQSSDATTGMRRYQAYLDYSQQHGLTPMVALGELSYQSGFQLAPQVITPQTSALVCAS
DTIAMGVSKYLQQQEREQPPIQVCGIGNTPLLHFLFPDTLTIELGYGRAGVKAAQQLLDQLSNSQPIQQIIIPGQLV

Sequences:

>Translated_317_residues
MQNRLTIKDIARMSGVGKSTVSRVLNNEGSVSPQTRERVEAVIRQHGFTPSKSARAMRGQSDKVVGIIVSRLDSPSENQA
VRTMLPLFYQQGYDPILMESQFDTTLVSEHLHILQQRHVDGVILFGFSGLTAEMLAPWQEKMVVLAREYRGFSSVCYDDE
GAIYLLMDKLRQAGHRHISYIGVQSSDATTGMRRYQAYLDYSQQHGLTPMVALGELSYQSGFQLAPQVITPQTSALVCAS
DTIAMGVSKYLQQQEREQPPIQVCGIGNTPLLHFLFPDTLTIELGYGRAGVKAAQQLLDQLSNSQPIQQIIIPGQLV
>Mature_317_residues
MQNRLTIKDIARMSGVGKSTVSRVLNNEGSVSPQTRERVEAVIRQHGFTPSKSARAMRGQSDKVVGIIVSRLDSPSENQA
VRTMLPLFYQQGYDPILMESQFDTTLVSEHLHILQQRHVDGVILFGFSGLTAEMLAPWQEKMVVLAREYRGFSSVCYDDE
GAIYLLMDKLRQAGHRHISYIGVQSSDATTGMRRYQAYLDYSQQHGLTPMVALGELSYQSGFQLAPQVITPQTSALVCAS
DTIAMGVSKYLQQQEREQPPIQVCGIGNTPLLHFLFPDTLTIELGYGRAGVKAAQQLLDQLSNSQPIQQIIIPGQLV

Specific function: Repressor of the treBC operon. Binds trehalose 6- phosphate as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=62.0253164556962, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1787906, Length=255, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790194, Length=299, Percent_Identity=28.0936454849498, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787948, Length=328, Percent_Identity=23.1707317073171, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790369, Length=307, Percent_Identity=25.0814332247557, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789202, Length=287, Percent_Identity=24.0418118466899, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI48994940, Length=317, Percent_Identity=24.2902208201893, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789068, Length=296, Percent_Identity=23.6486486486486, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787580, Length=301, Percent_Identity=24.9169435215947, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=25, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786540, Length=313, Percent_Identity=23.961661341853, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788474, Length=290, Percent_Identity=22.7586206896552, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786268, Length=285, Percent_Identity=23.1578947368421, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- InterPro:   IPR012771 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35172; Mature: 35172

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRLTIKDIARMSGVGKSTVSRVLNNEGSVSPQTRERVEAVIRQHGFTPSKSARAMRGQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCC
SDKVVGIIVSRLDSPSENQAVRTMLPLFYQQGYDPILMESQFDTTLVSEHLHILQQRHVD
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
GVILFGFSGLTAEMLAPWQEKMVVLAREYRGFSSVCYDDEGAIYLLMDKLRQAGHRHISY
EEEEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHCCCCEEEE
IGVQSSDATTGMRRYQAYLDYSQQHGLTPMVALGELSYQSGFQLAPQVITPQTSALVCAS
EEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEC
DTIAMGVSKYLQQQEREQPPIQVCGIGNTPLLHFLFPDTLTIELGYGRAGVKAAQQLLDQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHH
LSNSQPIQQIIIPGQLV
HCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MQNRLTIKDIARMSGVGKSTVSRVLNNEGSVSPQTRERVEAVIRQHGFTPSKSARAMRGQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCC
SDKVVGIIVSRLDSPSENQAVRTMLPLFYQQGYDPILMESQFDTTLVSEHLHILQQRHVD
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCC
GVILFGFSGLTAEMLAPWQEKMVVLAREYRGFSSVCYDDEGAIYLLMDKLRQAGHRHISY
EEEEEECCCCHHHHHCCHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHCCCCEEEE
IGVQSSDATTGMRRYQAYLDYSQQHGLTPMVALGELSYQSGFQLAPQVITPQTSALVCAS
EEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEECCCCCEEEEEC
DTIAMGVSKYLQQQEREQPPIQVCGIGNTPLLHFLFPDTLTIELGYGRAGVKAAQQLLDQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHH
LSNSQPIQQIIIPGQLV
HCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9148912; 7610040; 9278503; 7608078; 9865945 [H]