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The map label for this gene is yedY

Identifier: 218930673

GI number: 218930673

Start: 4082343

End: 4083443

Strand: Reverse

Name: yedY

Synonym: YPO3662

Alternate gene names: 218930673

Gene position: 4083443-4082343 (Counterclockwise)

Preceding gene: 218930674

Following gene: 218930672

Centisome position: 87.75

GC content: 49.95

Gene sequence:

>1101_bases
ATGCATAACACGTTTACTCATACTAAAAACAATACTCATACTAAAAACAATACTCAGGCTAAAAACAGCGGTTCTCAGAC
GAAAAGCAATGCGGTCAGTCTCAATAAGCCACGAAAACTGACTGAGGCAGATGTCACGCCAGAGAGTATTTTTTATCAAC
GACGTAAGGTGTTGCAGGCTCTGGGGATCACCGCCGCCACCTTGGCTTTGCCAGCATCAGCACAAGCCGATTTACTGGCC
TGGTTTAAAGGTAACGAGCCGCCCAAAGCGCCCTCAGGTAAACCATTGACGTTCACCCCATCAGCCGCTTACCACCCAGA
CTTGGCTTTAACGCCAGAAGACAAAGTGACCGGGTACAATAATTTCTATGAGTTTGGGTTGGATAAAGCTGATCCCGCCG
CGAATGCTGGCACGCTGAAAACAGAGGACTGGCAGATTAAGATTGACGGCGATGTCGTTAAGCCCATGACGTTGGATATG
GATTATCTGATGAAATGCTTTCCCCTTGAAGAGCGAATCTATCGCCTACGCTGCGTCGAAGCGTGGTCGATGGTCGTGCC
ATGGATCGGTTTTGAGTTAGGGAAACTGCTGAAATTAGCAGAGCCAACCAGTAACGCCCGCTATGTGGCGTTCCAAACAT
TGTATGCTCCAGATCAAATGCCTGGGCAGAAAAACCGCTTTATTGGCGGGGGACTGGACTACCCCTATGTCGAAGGGCTG
CGGTTGGATGAAGCCATGCACCCGCTGGCCTTTATGGTTGTTGGCGTGTATGGCAAAACCCTGCCACCACAAAATGGTGC
GCCACTACGACTCATGACACCGTGGAAATATGGCTTTAAGAGCATTAAATCCATCGTGCATATTCGCCTGACACGGGATC
AACCGCCAACCACCTGGAATTTGAGCGCCCCCAACGAATATGGCTTTTATGCCAATGTGAACCCGCACGTCGATCACCCC
CGCTGGTCACAGGCCACCGAGCGCGTTATCGGTTCTGGCGGTATTCTGGATGTAAAACGCCAGCCCACCCTGTTATTTAA
CGGCTATGCTGAACAAGTGGCATCGCTATATCGTGGTTTAGATTTGCGGAAGAATTTCTAA

Upstream 100 bases:

>100_bases
CTTAGAATCTTCGCACTTGTTCCCATTTGCCACCATGATTAACCACATCAGGGGCAACGCGATTAACGACATCAAGGGCA
ACTATCCGACGGAGTCTGCT

Downstream 100 bases:

>100_bases
TGCGGCTCAGTTTACGACACATCACATGGCTAAAAATCGCCATTTGGCTGGCGGCAACATTACCGCTTCTGTGGCTCGTA
TTATCGATCAATCTGGGGGG

Product: putative sulfite oxidase subunit YedY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MHNTFTHTKNNTHTKNNTQAKNSGSQTKSNAVSLNKPRKLTEADVTPESIFYQRRKVLQALGITAATLALPASAQADLLA
WFKGNEPPKAPSGKPLTFTPSAAYHPDLALTPEDKVTGYNNFYEFGLDKADPAANAGTLKTEDWQIKIDGDVVKPMTLDM
DYLMKCFPLEERIYRLRCVEAWSMVVPWIGFELGKLLKLAEPTSNARYVAFQTLYAPDQMPGQKNRFIGGGLDYPYVEGL
RLDEAMHPLAFMVVGVYGKTLPPQNGAPLRLMTPWKYGFKSIKSIVHIRLTRDQPPTTWNLSAPNEYGFYANVNPHVDHP
RWSQATERVIGSGGILDVKRQPTLLFNGYAEQVASLYRGLDLRKNF

Sequences:

>Translated_366_residues
MHNTFTHTKNNTHTKNNTQAKNSGSQTKSNAVSLNKPRKLTEADVTPESIFYQRRKVLQALGITAATLALPASAQADLLA
WFKGNEPPKAPSGKPLTFTPSAAYHPDLALTPEDKVTGYNNFYEFGLDKADPAANAGTLKTEDWQIKIDGDVVKPMTLDM
DYLMKCFPLEERIYRLRCVEAWSMVVPWIGFELGKLLKLAEPTSNARYVAFQTLYAPDQMPGQKNRFIGGGLDYPYVEGL
RLDEAMHPLAFMVVGVYGKTLPPQNGAPLRLMTPWKYGFKSIKSIVHIRLTRDQPPTTWNLSAPNEYGFYANVNPHVDHP
RWSQATERVIGSGGILDVKRQPTLLFNGYAEQVASLYRGLDLRKNF
>Mature_366_residues
MHNTFTHTKNNTHTKNNTQAKNSGSQTKSNAVSLNKPRKLTEADVTPESIFYQRRKVLQALGITAATLALPASAQADLLA
WFKGNEPPKAPSGKPLTFTPSAAYHPDLALTPEDKVTGYNNFYEFGLDKADPAANAGTLKTEDWQIKIDGDVVKPMTLDM
DYLMKCFPLEERIYRLRCVEAWSMVVPWIGFELGKLLKLAEPTSNARYVAFQTLYAPDQMPGQKNRFIGGGLDYPYVEGL
RLDEAMHPLAFMVVGVYGKTLPPQNGAPLRLMTPWKYGFKSIKSIVHIRLTRDQPPTTWNLSAPNEYGFYANVNPHVDHP
RWSQATERVIGSGGILDVKRQPTLLFNGYAEQVASLYRGLDLRKNF

Specific function: The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase

COG id: COG2041

COG function: function code R; Sulfite oxidase and related enzymes

Gene ontology:

Cell location: Periplasm. Note=Is attached to the inner membrane when interacting with the yedZ subunit (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yedY family

Homologues:

Organism=Escherichia coli, GI1788282, Length=334, Percent_Identity=75.4491017964072, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEDY_YERPE (Q8ZAW9)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AH0445
- RefSeq:   NP_667548.1
- RefSeq:   NP_995152.1
- RefSeq:   YP_002348548.1
- ProteinModelPortal:   Q8ZAW9
- SMR:   Q8ZAW9
- IntAct:   Q8ZAW9
- GeneID:   1145152
- GeneID:   1176483
- GeneID:   2765298
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3662
- KEGG:   ypk:y0205
- KEGG:   ypm:YP_3884
- HOGENOM:   HBG287041
- OMA:   HYNNFYE
- ProtClustDB:   PRK05363
- BioCyc:   YPES187410:Y0205-MONOMER
- BioCyc:   YPES214092:YPO3662-MONOMER
- HAMAP:   MF_01206
- InterPro:   IPR000572
- InterPro:   IPR006311
- InterPro:   IPR022867
- Gene3D:   G3DSA:3.90.420.10
- TIGRFAMs:   TIGR01409

Pfam domain/function: PF00174 Oxidored_molyb; SSF56524 Oxidored_molyb

EC number: NA

Molecular weight: Translated: 40979; Mature: 40979

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS51318 TAT

Important sites: BINDING 120-120 BINDING 213-213 BINDING 265-265 BINDING 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNTFTHTKNNTHTKNNTQAKNSGSQTKSNAVSLNKPRKLTEADVTPESIFYQRRKVLQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LGITAATLALPASAQADLLAWFKGNEPPKAPSGKPLTFTPSAAYHPDLALTPEDKVTGYN
HCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCC
NFYEFGLDKADPAANAGTLKTEDWQIKIDGDVVKPMTLDMDYLMKCFPLEERIYRLRCVE
CHHHHCCCCCCCCCCCCCEECCCEEEEECCCEECCEEECHHHHHHHCCHHHHHHHHHHHH
AWSMVVPWIGFELGKLLKLAEPTSNARYVAFQTLYAPDQMPGQKNRFIGGGLDYPYVEGL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEECCCCCCCHHCCE
RLDEAMHPLAFMVVGVYGKTLPPQNGAPLRLMTPWKYGFKSIKSIVHIRLTRDQPPTTWN
EHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHEEEEEEECCCCCCEEE
LSAPNEYGFYANVNPHVDHPRWSQATERVIGSGGILDVKRQPTLLFNGYAEQVASLYRGL
CCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCHHHHHHHHHHCC
DLRKNF
CCCCCC
>Mature Secondary Structure
MHNTFTHTKNNTHTKNNTQAKNSGSQTKSNAVSLNKPRKLTEADVTPESIFYQRRKVLQA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LGITAATLALPASAQADLLAWFKGNEPPKAPSGKPLTFTPSAAYHPDLALTPEDKVTGYN
HCCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCC
NFYEFGLDKADPAANAGTLKTEDWQIKIDGDVVKPMTLDMDYLMKCFPLEERIYRLRCVE
CHHHHCCCCCCCCCCCCCEECCCEEEEECCCEECCEEECHHHHHHHCCHHHHHHHHHHHH
AWSMVVPWIGFELGKLLKLAEPTSNARYVAFQTLYAPDQMPGQKNRFIGGGLDYPYVEGL
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEECCCCCCCHHCCE
RLDEAMHPLAFMVVGVYGKTLPPQNGAPLRLMTPWKYGFKSIKSIVHIRLTRDQPPTTWN
EHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHEEEEEEECCCCCCEEE
LSAPNEYGFYANVNPHVDHPRWSQATERVIGSGGILDVKRQPTLLFNGYAEQVASLYRGL
CCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCEEEECCHHHHHHHHHHCC
DLRKNF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430