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The map label for this gene is arcB [H]

Identifier: 218930567

GI number: 218930567

Start: 3962788

End: 3965124

Strand: Reverse

Name: arcB [H]

Synonym: YPO3555

Alternate gene names: 218930567

Gene position: 3965124-3962788 (Counterclockwise)

Preceding gene: 218930568

Following gene: 218930566

Centisome position: 85.2

GC content: 48.35

Gene sequence:

>2337_bases
ATGAAGCAAATCCGGGTATTAGCCCAGTACTATGTTGATTTAATGGTTAAATTAGGGCTGGTGCGTTTTTCGCTGCTACT
GGCATCGGCATTGGTGTTATTGGCGATGGTTGTTCAAATGGCCGTCACCTTCGTCTTGCGCGGCTCTGTTGAAACCCTCG
ATCTGGTGCGCTCCATTTTCTTTGGTTTGCTGATAACCCCTTGGGCCGTGTATTTCCTGTCGGTTGTGGTTGAGCAACTG
GAAGAGTCGCGCCAGCGCCTGTCCCGGTTGGTTGATAAGCTCGAAGTGATGCGTCATCGCGATCTCGAGCTGAACAAGCA
ACTGACAGAAAATATTACTCAACTGAATCAAGAGATTGTTGAACGCGAAAAAGCAGAGAAAGCGCATCTGCAAGTGGTCG
ATAAACTGAAAGAAGAGATGGGCCACCGCGAGCAGGCGCAGATTGAGCTGGGGCAGCAATCGGCCTTATTACGTTCTTTT
CTCGATGCTTCGCCAGATTTGGTTTATTACCGTAACGAAGATAATGAGTTTTCCGGTTGTAACCGCGCAATGGAATTGTT
GACGGGTAAAAGTGAGAAGCAACTGGTCGGATTGACGCCAAAAGATGTTTATGCACCAGATATCGCCGAGAAAGTGATGG
AGACCGATGAGAAAGTCTTCCGCCATAACGTTTCTCTTACCTACGAACAGTGGCTGGTTTACCCAGATGGCCGTAAAGCC
TGTTTTGAACTGCGTAAAGTGCCTTTTTATGACCGAGTCGGTAAACGACATGGGCTAATGGGCTTTGGACGCGATATAAC
CGAGCGTAAGCGCTACCAGGACGCGCTGGAGAATGCCAGTAGGGATAAGACGACATTTATCTCAACAATCAGCCACGAGC
TACGTACGCCGCTTAATGGCATTGTTGGCCTCAGTCGCATCTTGTTAGATACCGAATTAGATGCCGAACAACTGAAATAC
CTAAAAACCATTCATGTCAGTGCTATCACTCTTGGAAATATTTTCAACGATATCATTGAAATGGATAAGCTGGAGCGGCG
GAAAGTACAGCTTGATAATCAACCTGTTGATTTTACTGGGTTCATGGCCGATCTGGAAAACCTCTCCGGTTTACTGGTGC
AGCCAAAAGGATTGAAATTCATTATGGAACCGCAGTTGCCATTGCCGGAGAAAGTGATTGCCGATGGGACCCGGCTGCGC
CAAATCCTGTGGAACCTGATTGGTAATGCGGTGAAATTCACCCAGCAAGGCAAAATTGTGGTGCGGGTACGGCGTGAGGG
TAACGACCGCCTGATTTTTGAAGTCGAAGATTCAGGCATGGGGATACCGGAAGACGAACAAGATAAAATTTTCGCCATGT
ATTATCAGGTGAAAGATCGCAACGGGGGGCGCCCGGCCACGGGCACCGGTATCGGCCTCGCGGTATCTAAACGTCTGGCA
CAGAGTATGGGCGGTGATATTACGGTGAAAAGCACGCAGGGGGTGGGTTCTTGCTTCACCTTAACCATCAAGGCACCTGC
GGTACAGGAAGCCTCCAACGCGCCGTCAGGCGACGATATGCCATTACCTGCTCTTCATGTACTGCTGGTGGAAGATATCG
AGCTGAACGTCATTGTTGCGCGTTCAGTTCTGGAAAAATTGGGGAACAGTGTTGACGTGGCGATGAATGGCCACGATGCA
TTAGCCATGTTTAACCCTGAAGATTTTGATTTGGTTTTATTAGATATTCAGTTGCCTGATATGAGTGGGCTGGATATCGC
CCGGCAAATTCGGGCGGAATATGGCAAGCAGTCATTGCCCCCGTTGGTCGCATTAACCGCTAACGTTCTTAAAGATAAGA
AAGAATATTTAGATGCCGGCATGGACGACGTGCTGAGTAAGCCACTGTCAGTCCCTGCACTGACGGCCATGATTAAGCAA
TTTTGGGATAGTAAGCCCTCTTCAGCGGTACAAAAACAGGAGCATAAAGTGATGCAAACCCATGAATCGTTACTTGATAC
CACCATGTTGGAACAATACATCGATTTAGTTGGCCCACAGTTGATTCACCAAAGTCTGGAGATGTTTGAACAGATGATGC
CAGGTTATTTGGCGGTGCTGGATTCAAATATGACGGCGCGGGACCAAAAGGGGATCACGGAAGAAGCACACAAAATTAAA
GGGGCGGCAGGTTCTGTCGGTTTACGCCACATACAGCAACTGGCCCAACAGATTCAGACACCGACATTGCCAGCGTGGTG
GGATAACGTGCAGGACTGGGTCGATGAGTTAAAATTAGAATGGCGTAATGATGTTCAGGTATTGCGTGAGTGGGCAGCGG
AAGTTGAAAAAAAATAA

Upstream 100 bases:

>100_bases
CCCCGCGATTTGCAATCTTTTCCACACTTCTGAGTCACCTGGCTTATCTCTTTGTGGTTTTACGGTATGATTTATCCGAT
AAGCACTGACAGAGGTTGCT

Downstream 100 bases:

>100_bases
CCCCGACCGAGGCCGGGGTGCGCGAAGACTGCGCCAACACCAGGGAAAACGTTAACCTGCGTATTATTTCGATTTCGAGT
GAATTCGCAGGTTGTCAGGA

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIVEREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSF
LDASPDLVYYRNEDNEFSGCNRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELDAEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLR
QILWNLIGNAVKFTQQGKIVVRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLA
QSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMNGHDA
LAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQ
FWDSKPSSAVQKQEHKVMQTHESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIK
GAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK

Sequences:

>Translated_778_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIVEREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSF
LDASPDLVYYRNEDNEFSGCNRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELDAEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLR
QILWNLIGNAVKFTQQGKIVVRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLA
QSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMNGHDA
LAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQ
FWDSKPSSAVQKQEHKVMQTHESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIK
GAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK
>Mature_778_residues
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIVEREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSF
LDASPDLVYYRNEDNEFSGCNRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKA
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNGIVGLSRILLDTELDAEQLKY
LKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTGFMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLR
QILWNLIGNAVKFTQQGKIVVRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLA
QSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMNGHDA
LAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQ
FWDSKPSSAVQKQEHKVMQTHESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIK
GAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=781, Percent_Identity=76.1843790012804, Blast_Score=1191, Evalue=0.0,
Organism=Escherichia coli, GI87081816, Length=491, Percent_Identity=29.1242362525458, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1788713, Length=497, Percent_Identity=28.5714285714286, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789149, Length=502, Percent_Identity=28.8844621513944, Blast_Score=166, Evalue=7e-42,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=35.4838709677419, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1788549, Length=415, Percent_Identity=26.5060240963855, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=27.0194986072423, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=30.0469483568075, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=27.0042194092827, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=234, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=22.4770642201835, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=26.7489711934156, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=26.5822784810127, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=165, Percent_Identity=28.4848484848485, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87903; Mature: 87903

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSFLDASPDLVYYRNEDNEFSGC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
NRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKA
HHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHEEEECCCHHH
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELDAEQLKYLKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLRQILWNLIGNAVKFTQQGKIV
HHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEE
VRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
QSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVA
HHCCCCEEEEECCCCCCEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RSVLEKLGNSVDVAMNGHDALAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLP
HHHHHHCCCCEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
PLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQFWDSKPSSAVQKQEHKVMQT
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
HESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEEHHCCCCCCHHHCCCHHHHHHHC
GAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQIRVLAQYYVDLMVKLGLVRFSLLLASALVLLAMVVQMAVTFVLRGSVETLDLVRSIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVDKLEVMRHRDLELNKQLTENITQLNQEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EREKAEKAHLQVVDKLKEEMGHREQAQIELGQQSALLRSFLDASPDLVYYRNEDNEFSGC
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
NRAMELLTGKSEKQLVGLTPKDVYAPDIAEKVMETDEKVFRHNVSLTYEQWLVYPDGRKA
HHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEHEEEECCCHHH
CFELRKVPFYDRVGKRHGLMGFGRDITERKRYQDALENASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELDAEQLKYLKTIHVSAITLGNIFNDIIEMDKLERRKVQLDNQPVDFTG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FMADLENLSGLLVQPKGLKFIMEPQLPLPEKVIADGTRLRQILWNLIGNAVKFTQQGKIV
HHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEE
VRVRREGNDRLIFEVEDSGMGIPEDEQDKIFAMYYQVKDRNGGRPATGTGIGLAVSKRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
QSMGGDITVKSTQGVGSCFTLTIKAPAVQEASNAPSGDDMPLPALHVLLVEDIELNVIVA
HHCCCCEEEEECCCCCCEEEEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
RSVLEKLGNSVDVAMNGHDALAMFNPEDFDLVLLDIQLPDMSGLDIARQIRAEYGKQSLP
HHHHHHCCCCEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
PLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKQFWDSKPSSAVQKQEHKVMQT
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
HESLLDTTMLEQYIDLVGPQLIHQSLEMFEQMMPGYLAVLDSNMTARDQKGITEEAHKIK
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHEEHHCCCCCCHHHCCCHHHHHHHC
GAAGSVGLRHIQQLAQQIQTPTLPAWWDNVQDWVDELKLEWRNDVQVLREWAAEVEKK
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]