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The map label for this gene is phoP [H]

Identifier: 218930056

GI number: 218930056

Start: 3362417

End: 3363124

Strand: Direct

Name: phoP [H]

Synonym: YPO3009

Alternate gene names: 218930056

Gene position: 3362417-3363124 (Clockwise)

Preceding gene: 218930055

Following gene: 218930068

Centisome position: 72.25

GC content: 51.27

Gene sequence:

>708_bases
ATGAAAATATTAATTGCCGAAGACAATGCCCATATTCGTAATGGCCTTATGGAAGTATTGGCCCATGAAGGGTACCGCCC
CATCGCGGCAGAAAATGGTGTGCAGGCACTGGCGCTATACCGCCAACAACAGCCGGATTTTATCATTCTTGATATCATGA
TGCCGGAGCTTGATAGCTACAAGGTGTGCAGGGAGATCCGCAAACACGACTGGCAAACGCCCATTATTTTTCTGTCCGCG
AAGGATGAGGAGATTGACCGGGTGATCGGGTTAGAGTTGGGTGCTGACGACTACATCAGTAAGCCCTTCGGTATCCATGA
AATGCGCGCCCGAATCAAGACTATTGTCCGCCGTTGTCTACGAAAAGTACCTGAATCCGCCGAAGACGCAGGCTTCCCGT
TTGGCGATCTGATGGTGTTTCCCAATGAGTTGTGTGCGATTCGTGGAGAGACGCGCCTTGAGCTGTCACTGCGCGAGGTT
AATATCCTACGCTATCTGTATCAGCATAAGGGCCGGGTGGTCACCAGAGATATGTTATTTGATGCGGTTTGGGGATATGA
CCATTTGCCACAGAGCCGTACGCTCGACCAGCATATTTCCAAGCTTCGCAAGACCATTGAACTGGATCCGGTTCATCCGG
TATTGATCCGCACAGTGCACGGGGCGGGTTACCGTTATCAAGGCACGGCGCAGAGCCTGGAAAAATAG

Upstream 100 bases:

>100_bases
GCGAAATTTCCGTCACCAGTAATCCGGCGGGTAGCTGTTTTACCCTAAAACTGCCTATGACGATTAAGCAAGATGCGGCC
ACAGACAAGGAGCAGTTCAC

Downstream 100 bases:

>100_bases
ATCAATGAAAGTTTGCGGATAGATCCTGACAATCCCTTTGATATTTTCAACATAATAAGTTTCCTGCCCCCCCAGATAAC
CGGGATATTGTGTCTTGATT

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDSYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK

Sequences:

>Translated_235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDSYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
>Mature_235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDSYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=37.5545851528384, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=34.8017621145374, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=35.9649122807018, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.2678571428571, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=35.8407079646018, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=33.7606837606838, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=31.6017316017316, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=38.5964912280702, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=30.9734513274336, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=30.8035714285714, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=30.8035714285714, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=30.1724137931034, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.448275862069, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=27.1111111111111, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=37.5, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=33.6134453781513, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=28.9473684210526, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27162; Mature: 27162

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDSY
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
KVCREIRKHDWQTPIIFLSAKDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCL
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
RKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREVNILRYLYQHKGRVVTRDMLF
HHCCCCCHHCCCCCHHHEECCCHHHEECCCCEEEHHHHHHHHHHHHHHHCCCEEHHHHHH
DAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCEEECCCHHHHCC
>Mature Secondary Structure
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDSY
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
KVCREIRKHDWQTPIIFLSAKDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCL
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
RKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREVNILRYLYQHKGRVVTRDMLF
HHCCCCCHHCCCCCHHHEECCCHHHEECCCCEEEHHHHHHHHHHHHHHHCCCEEHHHHHH
DAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]