Click here to switch to the map view.

The map label for this gene is accD

Identifier: 218929840

GI number: 218929840

Start: 3102093

End: 3103007

Strand: Direct

Name: accD

Synonym: YPO2768

Alternate gene names: 218929840

Gene position: 3102093-3103007 (Clockwise)

Preceding gene: 218929839

Following gene: 218929841

Centisome position: 66.66

GC content: 49.51

Gene sequence:

>915_bases
ATGAGCTGGATTGAACGAATTCTTAACAAAAGCAATATCACACAAACCCGTAAAGCGAGTATTCCTGAAGGGGTATGGAC
AAAATGTGATAGCTGCGGTCAGGTACTTTATCGTGCTGAACTGGAGCGTAATCTGGAAGTGTGTCCTAAGTGTGATCACC
ATATGCGTATGTCAGCCCGTGCACGGTTGCATATGCTGTTGGATGCAGGCAGTGAAGTTGAATTGGGTAGCGAACTGGAG
CCGAAGGACATCCTGAAATTTAGGGATTCCAAAAAGTATAAAGATCGTATTTCAGCCGCACAAAAAGATACTGGCGAGAA
AGATGCTCTGGTTGCCATGAAAGGGACGCTGCAAGGGATGCCTATCGTTGCCGCCTCGTTTGAATTTGCCTTTATGGGCG
GTTCAATGGCGTCGGTGGTTGGTGCTCGCTTTGTACGTGCCGTTGAACAGGCTCTGGAAGATAATTGCCCATTGGTCTGT
TTCTCCTCCAGTGGTGGTGCACGTATGCAGGAAGCGTTGATGTCATTGATGCAGATGGCAAAGACCAGTGCAGCGCTGGC
TAAAATGCAAGAGCGCGGTTTACCCTACATTTCTGTGCTGACTGACCCTACCATGGGCGGTGTTTCTGCTAGCCTGGCCA
TGTTAGGTGATATCAATATCGCTGAGCCAAAAGCGTTAATCGGCTTTGCTGGCCCACGTGTTATTGAGCAAACCGTGCGC
GAAAAACTGCCGCCTGGCTTCCAGCGCAGTGAGTTTCTGATTGAAAAAGGCGCGATTGATATGATCGTTCGCCGTCCAGT
TATGCGGCAGACTTTGGCGAGCATTTTGTCTAAATTGACTCATCAGCCGCAGCCAAGCGTGGTTGAGAGCAAAGCAGATA
CCGTGGCCCAGCCTGAAAATCAGGCAGATGTCTGA

Upstream 100 bases:

>100_bases
GCGTGTATCTCAGGCATTTTTTATTGGAGAGTTTTCAGGGAGATGGTTAAAGCATGAACAGCGGACTGGCAACAGCCAGG
TTCAAACAGAAAGGTCATCG

Downstream 100 bases:

>100_bases
TTAACTCAACGGGCATCACTCTTGTAAGATGGTGCCCGGTTATTGTGCCTTATCAGAAAATAAGCGTTATTTAATAACGA
CAATTTGGCAATAACGAGTG

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELE
PKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVC
FSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVR
EKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV

Sequences:

>Translated_304_residues
MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELE
PKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVC
FSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVR
EKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV
>Mature_303_residues
SWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARARLHMLLDAGSEVELGSELEP
KDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGMPIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCF
SSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVRE
KLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPENQADV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Homo sapiens, GI119943100, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788655, Length=298, Percent_Identity=86.241610738255, Blast_Score=528, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_YERP3 (A7FGM3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400401.1
- ProteinModelPortal:   A7FGM3
- SMR:   A7FGM3
- STRING:   A7FGM3
- GeneID:   5388107
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1422
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- BioCyc:   YPSE349747:YPSIP31758_1422-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33274; Mature: 33143

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSAR
CCHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARLHMLLDAGSEVELGSELEPKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGM
HHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCHHEEEECCCCCCC
PIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCFSSSGGARMQEALMSLMQMA
CEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
KTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVR
HHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
EKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPEN
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
QADV
CCCC
>Mature Secondary Structure 
SWIERILNKSNITQTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSAR
CHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARLHMLLDAGSEVELGSELEPKDILKFRDSKKYKDRISAAQKDTGEKDALVAMKGTLQGM
HHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCHHEEEECCCCCCC
PIVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLVCFSSSGGARMQEALMSLMQMA
CEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHH
KTSAALAKMQERGLPYISVLTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVR
HHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHH
EKLPPGFQRSEFLIEKGAIDMIVRRPVMRQTLASILSKLTHQPQPSVVESKADTVAQPEN
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCC
QADV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA