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The map label for this gene is hoxN [H]

Identifier: 218929746

GI number: 218929746

Start: 2998797

End: 2999855

Strand: Direct

Name: hoxN [H]

Synonym: YPO2673

Alternate gene names: 218929746

Gene position: 2998797-2999855 (Clockwise)

Preceding gene: 218929745

Following gene: 218929748

Centisome position: 64.44

GC content: 41.27

Gene sequence:

>1059_bases
ATGACGACAATAATCGCCAGCAGCAGCGCCTTTGGTAATCAGCAAACAAAGCGCAGAGCCATCTACCTGCTAATCGGCCT
GTTGGTGGTGAATGGGTTAGCTTGGGTCTGGGCTTTTGCTGAATTTAATGATAATGCCGTGCTGATGGGAATGGCTTTCC
TGGCCTACAGTTTTGGTTTGCGCCATGCGGTTGATGCGGATCATATTGCGGCTATTGATAACGTCACGCGTAAACTCATG
CAACAAGGTAAAACACCGATTGCTGTTGGGACTTTTTTCTCACTCGGCCATTCAACTATTGTGATCTTAGCTTCACTGGC
AATTGCTGCGACCGCCATGGCATTTAAGAATAATATGGCGTGGTTTCACGAAACCGGTGGTTTAATCGGGACGTTGGTGT
CATCCGTTTTTTTATTGTTATTTGCTTTTCTCAATTTAACGATCCTGATTTCAGTGTATAAAAAATTCAAACAAGTTAAA
GCTGGGTATATTTATAAAGATGAAGAGCTTGACCTTCTGGTCGTGAATAACGGTGGTCTGTTATCCAGAATGTTTAAACG
TGTATTTAATATGGTCAATAAAAGCTGGCATATGTATCCAGTTGGTTTTTTGTTTGGCTTAGGTTTTGATACCGCAACTG
AAATTGGTGTTTTGGGGATATCAGCGGCCAGCGCCACTCACGGTATGAATTTGTGGTCGATAATGGTGTTTCCGATTTTA
TTTGCGGCCGGAATGGCATTGATCGATTCACTGGATAATTTTGTGATGATTGGTGCTTATGGCTGGGCATTTTCTAAACC
TGTTCGTAAACTTTATTACAATATCACTATCACCGCTGCGTCGGTGATTATTGCTTTCTTTATCGGTGGCATTGAAGCCT
TGGGTTTGATTGCCGATAAGTTAAATTTAACTGGTGGTATCTGGACGCCAATTAATAATATCAGCGAGAACTTAGGTCAG
ATCGGTTACTGGATTATAGGGATGTTTATATGTTGCTGGTTAGTTTCTATTATTAATTACTATGTCCGTGGTTATGACAA
GCTAAATATAAGCCGATAA

Upstream 100 bases:

>100_bases
TTTATCGATCATATAGACCTCAAATTATTGGCGTTATCGTGTTGTCAGCGATAACGCCAGGTCAGAACGGGTAGGGTTGA
AAATAATCTGGAGTGCGAAT

Downstream 100 bases:

>100_bases
GTCATATTTATTGCGAGTGAATTATTAGACCCGCTGACACAATAAGTTGTATGTGCGTTGGTTAGGGAAGGCTAACAAAT
AGAGACACTCATTAACCGAT

Product: putative nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLM
QQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVK
AGYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQ
IGYWIIGMFICCWLVSIINYYVRGYDKLNISR

Sequences:

>Translated_352_residues
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLM
QQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVK
AGYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQ
IGYWIIGMFICCWLVSIINYYVRGYDKLNISR
>Mature_351_residues
TTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGLRHAVDADHIAAIDNVTRKLMQ
QGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMAWFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVKA
GYIYKDEELDLLVVNNGGLLSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPILF
AAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADKLNLTGGIWTPINNISENLGQI
GYWIIGMFICCWLVSIINYYVRGYDKLNISR

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 38706; Mature: 38575

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGL
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMA
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
WFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVKAGYIYKDEELDLLVVNNGGL
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCH
LSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
HHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHHHHHHHHHH
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADK
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TTIIASSSAFGNQQTKRRAIYLLIGLLVVNGLAWVWAFAEFNDNAVLMGMAFLAYSFGL
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMQQGKTPIAVGTFFSLGHSTIVILASLAIAATAMAFKNNMA
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
WFHETGGLIGTLVSSVFLLLFAFLNLTILISVYKKFKQVKAGYIYKDEELDLLVVNNGGL
EEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCH
LSRMFKRVFNMVNKSWHMYPVGFLFGLGFDTATEIGVLGISAASATHGMNLWSIMVFPIL
HHHHHHHHHHHHCCCCCEEHHHHHHHCCCCCHHHHHEEEEEHHHHHCCCHHHHHHHHHHH
FAAGMALIDSLDNFVMIGAYGWAFSKPVRKLYYNITITAASVIIAFFIGGIEALGLIADK
HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTGGIWTPINNISENLGQIGYWIIGMFICCWLVSIINYYVRGYDKLNISR
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]