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The map label for this gene is kch [H]

Identifier: 218929748

GI number: 218929748

Start: 3000971

End: 3002146

Strand: Direct

Name: kch [H]

Synonym: YPO2675

Alternate gene names: 218929748

Gene position: 3000971-3002146 (Clockwise)

Preceding gene: 218929746

Following gene: 218929751

Centisome position: 64.49

GC content: 41.41

Gene sequence:

>1176_bases
ATGAAAACATTACGGGAATTTAGAGCTAAGGTATCGGTACCCATTTTTCTTGCCATTTTGGTGGCAATTAACGGGTATCT
GATTTTAAGCCCGCTACTCTATCGGGCGATTGCACATTCAAGCGATGCAATAAATAACTTCAATACTTGGAAGGAGGCGT
TAAGTTTTCTGGAATTATTCGAAATCCCGCAATTTATGATCGGTCTGGTCTTGATGTTGATGGCATATGCACTATCAATG
AAAACCCGTACAGCATGGTTTTTATCGGTATTGCTGCTATTTACTCTTGTTGCCATCAATATTTTTATCGCGAAAAAATA
TGATAGCCTGACGATTTACTCCATCGTGATTATCTTAGCACTGCTCTTTTATTGGCGGCGGTTTGATTATTACAGTCTTG
GCAGCGGTACATTCTTTGCTGTTGTGAGTATCGCTTCATTAATCGTCTATAGCATGTTGGGTACGCTCTATATGGGTGAT
GAATTTGCCCCCGTAGTGACTGATTTATCTACAGCATTCTATTTCGCGATAGTGTGTATGTCGACGGTGGGGTTCGGGGA
TATTATCCCGCATACCACTGTGGCGAGAATGTTTACTCTTACGGTGATTATTGCTGGTATAACTGTTTTTGCTACCTCAG
TGGCTTCGATTGCCGGCCCGATGATCAGTAATAATATCAAACGCATAGTTAAAGGTAGGATTTCTCACGTGGAACGTAAA
AATCATTTTATTATTGTCGGTACCAACTCTTTGGCACTGAATGTATATAAAGGTCTGCGTGACCGGGGTGATGATGTCAC
TGTGGTTTGTGCGGTAGGTAGCCAACATGATTTCCCTTCCGATGCTGATATTATCGAGGGTGACCCTTCTTCTGTTGCCA
CGCTAAAATTAGCCGGTGCGGCGAAGGCAAAATATATTATCGTGTTGTGTAACAATGATGCTGATAACACCTTTACCATT
TTAGCGGCTAAAGAAATTTCGGGTGAGGGGACGAAAATACTGGCATTAGTCAATGAAACTCAGAATATAGAAAAAGTTAA
AAGAGTCAATCCAGACATGGTCTTCTCTTTGCCATTGTTAGGCAGTGAGTTACTGGTCAGGACTCTGAATGGCGATACCA
TCAATAATACCCTTATTACGGAAATGTTCTTTGGTCATTGCCAGAAACTGGATTGA

Upstream 100 bases:

>100_bases
TATCATTTGATTTCTATCAAAAATAATTTAATTTAATCATGATTTTTCTCATTTCTTATCTATACTAAAATTACCTATAA
CAATTCTAGTTACTCTATCG

Downstream 100 bases:

>100_bases
TATCATTAATAGCCCACTATCACTGTGTTTATATCAAAACACCCTCGGTTAAGTGAGGGTGTTTTTTTTGTCACGAGCCT
TGGTTTTTATGGGCTATTTA

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKTLREFRAKVSVPIFLAILVAINGYLILSPLLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLMLMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNSLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD

Sequences:

>Translated_391_residues
MKTLREFRAKVSVPIFLAILVAINGYLILSPLLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLMLMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNSLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD
>Mature_391_residues
MKTLREFRAKVSVPIFLAILVAINGYLILSPLLYRAIAHSSDAINNFNTWKEALSFLELFEIPQFMIGLVLMLMAYALSM
KTRTAWFLSVLLLFTLVAINIFIAKKYDSLTIYSIVIILALLFYWRRFDYYSLGSGTFFAVVSIASLIVYSMLGTLYMGD
EFAPVVTDLSTAFYFAIVCMSTVGFGDIIPHTTVARMFTLTVIIAGITVFATSVASIAGPMISNNIKRIVKGRISHVERK
NHFIIVGTNSLALNVYKGLRDRGDDVTVVCAVGSQHDFPSDADIIEGDPSSVATLKLAGAAKAKYIIVLCNNDADNTFTI
LAAKEISGEGTKILALVNETQNIEKVKRVNPDMVFSLPLLGSELLVRTLNGDTINNTLITEMFFGHCQKLD

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=332, Percent_Identity=39.1566265060241, Blast_Score=232, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 43098; Mature: 43098

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CHHHHHEECCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CHHHHHEECCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]