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The map label for this gene is nagA [H]

Identifier: 218929707

GI number: 218929707

Start: 2951035

End: 2952180

Strand: Reverse

Name: nagA [H]

Synonym: YPO2626

Alternate gene names: 218929707

Gene position: 2952180-2951035 (Counterclockwise)

Preceding gene: 218929708

Following gene: 218929706

Centisome position: 63.44

GC content: 48.34

Gene sequence:

>1146_bases
ATGTACGCTTTAACTCACGGCCGTATTTATACCAGCCATGAAGTACTGGATAATCATGCTGTTGTCGTTGCTGATGGATT
GATCGAACGTATCTGTCCTGTCGATGAACTTCCGGCTGGTATTGAGATATGCGATTTGGGTGGTGCCATTCTGGCCCCCG
GTTTTATCGATGTTCAGCTCAATGGCTGCGGTGGTGTGCAGTTCAATGACTCTCTCGAGGCTATCTCAGCAGAGACGTTG
GATATCATGCAGCGAGCCAATGAAAAATCAGGTTGTACCAGCTTCCTACCCACACTGATTACCTGCAGCGATGAATTTAT
GAAGCACGGCGTTGATGTCATGCGTTCATATCTGCAAAAAAACCAGCATCAGGCGCTCGGCTTGCACCTTGAAGGCCCTT
ATATCAGCCCACTGAAGAAAGGCACCCACAACCCGGCCTTTATCCGTAAGCCCAGCGCTGAAATGATTGACTATCTGTGT
GCCAATGCCGATGTGATCACCAAACTCACTCTGGCACCTGAAATGGTTGATCCTAAATATATACAGCAGCTCACAGAAGC
AGGTATTTTGGTTTCTGCCGGGCACTCAAACGCAACCTATCAGCAAGCCCGTCAAGGGTTTACCGCCGGTATCCGATTTG
CGACCCACCTTTATAATGCAATGCCGTACATTTCGGGGCGTGAACCGGGCCTTATTGGGGCCATTTTTGATACACCAGAG
GTATACACAGGCGTGATTGCCGATGGCCTGCATGTTGACTGGGCCAATATTCGCAATGCTAAGCGCCTAAAAGGCGAAAA
ACTGGTGCTGGTAACCGATGCCACTGCGCCTGCCGGTGCTAAAATTGAACAATTTATTTTTGCTGGCAAAACAATATACT
ATCGCGATGGTTTATGCGTAGACGAAAATGGCACATTAAGCGGTTCGGCACTAACCATGATTGAAGCGGTGCAAAACAGT
GTCGAACATGTCGGTATCGCGCTGGATGAAGCCCTGCGTATGGCAACACTTTATGCGGCCCGCGCCATTGGCGTGGATAA
ACAGTTAGGAAGTATTGAAGTCGGCAAAGTTGCCAACCTGACTGCCTTTACCCGCGATTATAAAATCACTAAAACCATCG
TTAATGGCAACGAGGTTTTATCATAA

Upstream 100 bases:

>100_bases
GAACCTTCCACGATGGAACTGAAAGTCAAAACCGTGAAATATTTCCGCGAATTAGAAGCTGAAAACGTAAAAGATCTTTA
ATGACTATTAGGGGGCTCAG

Downstream 100 bases:

>100_bases
GCGAGTAACTTTATTGATGAGCACCGGCGGACAAGCACAAATTGGTAACGTGGATCTGGTAAAACAACTCAATGGAGCCG
CGGTTTACCGGCTAATTGAT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MYALTHGRIYTSHEVLDNHAVVVADGLIERICPVDELPAGIEICDLGGAILAPGFIDVQLNGCGGVQFNDSLEAISAETL
DIMQRANEKSGCTSFLPTLITCSDEFMKHGVDVMRSYLQKNQHQALGLHLEGPYISPLKKGTHNPAFIRKPSAEMIDYLC
ANADVITKLTLAPEMVDPKYIQQLTEAGILVSAGHSNATYQQARQGFTAGIRFATHLYNAMPYISGREPGLIGAIFDTPE
VYTGVIADGLHVDWANIRNAKRLKGEKLVLVTDATAPAGAKIEQFIFAGKTIYYRDGLCVDENGTLSGSALTMIEAVQNS
VEHVGIALDEALRMATLYAARAIGVDKQLGSIEVGKVANLTAFTRDYKITKTIVNGNEVLS

Sequences:

>Translated_381_residues
MYALTHGRIYTSHEVLDNHAVVVADGLIERICPVDELPAGIEICDLGGAILAPGFIDVQLNGCGGVQFNDSLEAISAETL
DIMQRANEKSGCTSFLPTLITCSDEFMKHGVDVMRSYLQKNQHQALGLHLEGPYISPLKKGTHNPAFIRKPSAEMIDYLC
ANADVITKLTLAPEMVDPKYIQQLTEAGILVSAGHSNATYQQARQGFTAGIRFATHLYNAMPYISGREPGLIGAIFDTPE
VYTGVIADGLHVDWANIRNAKRLKGEKLVLVTDATAPAGAKIEQFIFAGKTIYYRDGLCVDENGTLSGSALTMIEAVQNS
VEHVGIALDEALRMATLYAARAIGVDKQLGSIEVGKVANLTAFTRDYKITKTIVNGNEVLS
>Mature_381_residues
MYALTHGRIYTSHEVLDNHAVVVADGLIERICPVDELPAGIEICDLGGAILAPGFIDVQLNGCGGVQFNDSLEAISAETL
DIMQRANEKSGCTSFLPTLITCSDEFMKHGVDVMRSYLQKNQHQALGLHLEGPYISPLKKGTHNPAFIRKPSAEMIDYLC
ANADVITKLTLAPEMVDPKYIQQLTEAGILVSAGHSNATYQQARQGFTAGIRFATHLYNAMPYISGREPGLIGAIFDTPE
VYTGVIADGLHVDWANIRNAKRLKGEKLVLVTDATAPAGAKIEQFIFAGKTIYYRDGLCVDENGTLSGSALTMIEAVQNS
VEHVGIALDEALRMATLYAARAIGVDKQLGSIEVGKVANLTAFTRDYKITKTIVNGNEVLS

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=377, Percent_Identity=32.8912466843501, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI224922791, Length=374, Percent_Identity=32.8877005347594, Blast_Score=158, Evalue=7e-39,
Organism=Escherichia coli, GI1786892, Length=381, Percent_Identity=75.0656167979003, Blast_Score=601, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI17553768, Length=351, Percent_Identity=31.6239316239316, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=32.5581395348837, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=32.1695760598504, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41143; Mature: 41143

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTHGRIYTSHEVLDNHAVVVADGLIERICPVDELPAGIEICDLGGAILAPGFIDVQL
CCEEECCEEEECHHHHCCCEEEEECHHHHHHCCCCCCCCCCEEEECCCHHHCCCEEEEEE
NGCGGVQFNDSLEAISAETLDIMQRANEKSGCTSFLPTLITCSDEFMKHGVDVMRSYLQK
CCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NQHQALGLHLEGPYISPLKKGTHNPAFIRKPSAEMIDYLCANADVITKLTLAPEMVDPKY
CCCCEEEEEECCCCCCHHHCCCCCCCEEECCCHHHHHHHHCCCCCEEEEECCCCCCCHHH
IQQLTEAGILVSAGHSNATYQQARQGFTAGIRFATHLYNAMPYISGREPGLIGAIFDTPE
HHHHHHCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
VYTGVIADGLHVDWANIRNAKRLKGEKLVLVTDATAPAGAKIEQFIFAGKTIYYRDGLCV
HHHHHHHCCCEEEHHHCCCHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCEEE
DENGTLSGSALTMIEAVQNSVEHVGIALDEALRMATLYAARAIGVDKQLGSIEVGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCH
TAFTRDYKITKTIVNGNEVLS
HHHHCCCEEEEEEECCHHHCC
>Mature Secondary Structure
MYALTHGRIYTSHEVLDNHAVVVADGLIERICPVDELPAGIEICDLGGAILAPGFIDVQL
CCEEECCEEEECHHHHCCCEEEEECHHHHHHCCCCCCCCCCEEEECCCHHHCCCEEEEEE
NGCGGVQFNDSLEAISAETLDIMQRANEKSGCTSFLPTLITCSDEFMKHGVDVMRSYLQK
CCCCCCEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NQHQALGLHLEGPYISPLKKGTHNPAFIRKPSAEMIDYLCANADVITKLTLAPEMVDPKY
CCCCEEEEEECCCCCCHHHCCCCCCCEEECCCHHHHHHHHCCCCCEEEEECCCCCCCHHH
IQQLTEAGILVSAGHSNATYQQARQGFTAGIRFATHLYNAMPYISGREPGLIGAIFDTPE
HHHHHHCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCH
VYTGVIADGLHVDWANIRNAKRLKGEKLVLVTDATAPAGAKIEQFIFAGKTIYYRDGLCV
HHHHHHHCCCEEEHHHCCCHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCEEE
DENGTLSGSALTMIEAVQNSVEHVGIALDEALRMATLYAARAIGVDKQLGSIEVGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCH
TAFTRDYKITKTIVNGNEVLS
HHHHCCCEEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]