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The map label for this gene is nagC [H]

Identifier: 218929706

GI number: 218929706

Start: 2949792

End: 2951021

Strand: Reverse

Name: nagC [H]

Synonym: YPO2625

Alternate gene names: 218929706

Gene position: 2951021-2949792 (Counterclockwise)

Preceding gene: 218929707

Following gene: 218929705

Centisome position: 63.41

GC content: 50.16

Gene sequence:

>1230_bases
TTGATGAGCACCGGCGGACAAGCACAAATTGGTAACGTGGATCTGGTAAAACAACTCAATGGAGCCGCGGTTTACCGGCT
AATTGATCAGCAAGGCCCGATTTCTCGCATACAGATTGCCGATCTCAGCCAGCTAGCCCCCGCCAGTGTCACCAAAATCA
CCCGGCAATTGTTGGAGCGCGGGCTGATCAAAGAGGTCGATCAGCAAGCCTCCACCGGGGGGCGTCGCGCTATCTCTATC
GTGACGGAAAACCGCCAATTCCATACCGTTGCAGTCCGTTTAGGTCGTAATGATGCCACGATCACCCTCTTTGACATGAG
CGGTAAATCGCTGGGTGAAGAGCACTATGCCCTGCCAGAACGAACACAAGAAACGCTGGAACACGCCTTATTTAATATCA
TCAGTCAGTTTATTGACGCCTATCAGCGTAAATTACGTGAACTGATTGCCATCGCGGTTATCCTGCCTGGGCTGGTTGAG
CAAAGCAAAGGTATCGTGCGCTATATGCCGCATATCAGTGTCAGTAACTGGCCGTTAGTCGATAATCTACAAGCGCGCTT
TAACGTCACCAGTTTTGTGGGTCACGATATCCGCAGCCTGGCACTGGCCGAGCACTATTTTGGTGCAACCCGTGACTGTG
AAGACTCCATTTTGGTTCGTCTACATCGAGGCACGGGTGCCGGTATTATCGTTAACAGCCAAATATTTTTAGGCAGCAAC
GGCAACGTTGGCGAGATAGGCCATATTCAGATTGATCCATTAGGTGATCGCTGCTATTGCGGTAACTTTGGTTGTCTGGA
AACCGTGGCATCCAACGCCGCGATTGAAAACCGCGTCAAGCACCTTCTCACCCAGGGTTATCCAAGTAAGCTGTCTCTTG
ATGACTGCCATATTGGTGCTATCTGTAAGGCCGCAAACCGCGGTGACTTGCTGGCCTGCGAAGTGATTGAACATGTTGGT
CGCTACTTGGGGAAAGCCATTGCTATCACCATAAACTTATTCAACCCACAAAAAGTGGTGATTGCCGGTGAAATTATTGA
AGCCGAGAAAATCCTACTACCCGCCATTCAGGGTTGCATTAATACGCAAGTTTTGAAAAACTTCCGCCAAAACCTGCCGA
TAGTGACATCACAACTTAACCACCAGTCGGCTATCGGCGCTTTCGCACTGGCTAAGCGCGCTATGCTCAATGGTGTCTTG
CTGCAACGTTTGCTAGAAACTCACCCGTAG

Upstream 100 bases:

>100_bases
GTCGGCAAAGTTGCCAACCTGACTGCCTTTACCCGCGATTATAAAATCACTAAAACCATCGTTAATGGCAACGAGGTTTT
ATCATAAGCGAGTAACTTTA

Downstream 100 bases:

>100_bases
GTTGAAAGAAACTGTCATGGTCACAGCCATGTTATAGTGACCTATTGCCGCGCTAAATGAGTAATATAAACAATGACAAT
CAAAAGCGTTATTTGCGATA

Product: putative N-acetylglucosamine regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MMSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISI
VTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVE
QSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNSQIFLGSN
GNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRGDLLACEVIEHVG
RYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVL
LQRLLETHP

Sequences:

>Translated_409_residues
MMSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISI
VTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVE
QSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNSQIFLGSN
GNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRGDLLACEVIEHVG
RYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVL
LQRLLETHP
>Mature_409_residues
MMSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISI
VTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPERTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVE
QSKGIVRYMPHISVSNWPLVDNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNSQIFLGSN
GNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGAICKAANRGDLLACEVIEHVG
RYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCINTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVL
LQRLLETHP

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=302, Percent_Identity=23.841059602649, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786891, Length=405, Percent_Identity=78.0246913580247, Blast_Score=657, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=400, Percent_Identity=40.25, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI87082127, Length=333, Percent_Identity=21.9219219219219, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790522, Length=296, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=22.7941176470588, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082230, Length=267, Percent_Identity=26.2172284644195, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44727; Mature: 44727

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLER
CCCCCCCCEECCHHHHHHCCCHHEEHHHCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHH
GLIKEVDQQASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPE
HHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCHHCCCCH
RTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVEQSKGIVRYMPHISVSNWPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
DNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNSQIFLGSN
CCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCC
GNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGA
CCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
ICKAANRGDLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCI
HHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHH
NTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVLLQRLLETHP
HHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIADLSQLAPASVTKITRQLLER
CCCCCCCCEECCHHHHHHCCCHHEEHHHCCCCCCCEEEECCHHHCCCHHHHHHHHHHHHH
GLIKEVDQQASTGGRRAISIVTENRQFHTVAVRLGRNDATITLFDMSGKSLGEEHYALPE
HHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEEEECCCCCCCCHHCCCCH
RTQETLEHALFNIISQFIDAYQRKLRELIAIAVILPGLVEQSKGIVRYMPHISVSNWPLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
DNLQARFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNSQIFLGSN
CCCHHHEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCC
GNVGEIGHIQIDPLGDRCYCGNFGCLETVASNAAIENRVKHLLTQGYPSKLSLDDCHIGA
CCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
ICKAANRGDLLACEVIEHVGRYLGKAIAITINLFNPQKVVIAGEIIEAEKILLPAIQGCI
HHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHH
NTQVLKNFRQNLPIVTSQLNHQSAIGAFALAKRAMLNGVLLQRLLETHP
HHHHHHHHHHCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]