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The map label for this gene is nuoA

Identifier: 218929641

GI number: 218929641

Start: 2869843

End: 2870337

Strand: Reverse

Name: nuoA

Synonym: YPO2555

Alternate gene names: 218929641

Gene position: 2870337-2869843 (Counterclockwise)

Preceding gene: 218929642

Following gene: 218929640

Centisome position: 61.68

GC content: 49.9

Gene sequence:

>495_bases
ATGTCAACAACCACTGAAATTATCGCTCATCACTGGGCGTTCGCTGTATTCCTCATCGGCGCTGTTGGGCTGTGCGGTTT
GATGCTTTTAGGTGCGTACTTCCTCGGGGGGAGAGCCCAGGCTCGTGCCAAAAACGTGCCTTATGAATCAGGTATAGATT
CAGTAGGCTCTGCGCGTATGCGCCTGTCCGCCAAGTTTTATCTGGTTGCGATGTTTTTCGTTATTTTCGATGTTGAAGCC
CTCTACCTTTATGCCTGGTCAATCTCCATTCGTGAGAGTGGCTGGATAGGCTTTATCGAAGCAGCCATTTTCATTTTGGT
GCTCTTGGCTGGTTTGTTTTATCTGGTGCGCATTGGTGCCCTGGATTGGACTCCTACACGTTCTAATCGTCGTGTGAGCA
AACCCAGTACCGTGAGATACGCCAGCAGTCATCCGCAAGATATATCCCAAGAGCTTAGCGTTGCAGGTAGCCAGCAAGCG
AACGAATCCCGATAA

Upstream 100 bases:

>100_bases
AGTGTGGTTTTTAATCCTTCCCTTTGAATCGATGTGGTGCACTAACTGCCAATACAAGAGCAGCATGTCCGACGCCACTT
TTGATGAGTAAGCAATGCGT

Downstream 100 bases:

>100_bases
GCTGATATCAGTCAGTGATTCGGGTCAGTGAACCTAGCTAACAGCCCAGCAGCGTCAAGTGCAAAAGGTATAGTGGTCAA
TAAATATAGCGAGGCATTAA

Product: NADH dehydrogenase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDVEA
LYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQA
NESR

Sequences:

>Translated_164_residues
MSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDVEA
LYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQA
NESR
>Mature_163_residues
STTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARMRLSAKFYLVAMFFVIFDVEAL
YLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGALDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQAN
ESR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=137, Percent_Identity=81.021897810219, Blast_Score=233, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_YERP3 (A7FGQ5)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400433.1
- STRING:   A7FGQ5
- GeneID:   5387299
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1454
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   FIEATIF
- ProtClustDB:   PRK06602
- BioCyc:   YPSE349747:YPSIP31758_1454-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 18089; Mature: 17958

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4d09a940)-; HASH(0x4d1c4474)-; HASH(0x4d1b77c0)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
RLSAKFYLVAMFFVIFDVEALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQANESR
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
STTTEIIAHHWAFAVFLIGAVGLCGLMLLGAYFLGGRAQARAKNVPYESGIDSVGSARM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHH
RLSAKFYLVAMFFVIFDVEALYLYAWSISIRESGWIGFIEAAIFILVLLAGLFYLVRIGA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LDWTPTRSNRRVSKPSTVRYASSHPQDISQELSVAGSQQANESR
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA