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The map label for this gene is hexA [H]

Identifier: 218929642

GI number: 218929642

Start: 2871021

End: 2871953

Strand: Reverse

Name: hexA [H]

Synonym: YPO2556

Alternate gene names: 218929642

Gene position: 2871953-2871021 (Counterclockwise)

Preceding gene: 218929643

Following gene: 218929641

Centisome position: 61.71

GC content: 46.84

Gene sequence:

>933_bases
ATGACAAATGCAAATCGTCCGATAATTAATCTCGACCTCGATCTGCTTAGAACCTTTGTAGCTGTTGCTGACTTAAATAC
TTTTGCTGCTGCTGCTGCTGCGGTCTGCCGAACTCAGTCAGCAGTTAGCCAACAAATGCAACGGTTAGAACAGTTAGTCG
GTAAGGAGTTATTTGCCCGCCACGGGCGTAACAAATTACTCACTGAACATGGTCTCCAGCTACTTGGCTATGCCAGAAAA
ATCTTACGTTTTAATGATGAAGCTTGTACATCACTCATGTACAGCAATATGGAAGGGTCACTTATTATCGGCGCATCTGA
TGATACTGCCGATACGTTACTGCCTTTCTTGCTGAACCGAGTGGCAACACTATACCCTCGGCTGGCGATAGATGTGCGGG
TAAAGCGCAGCCCATTTATCGCTGATATGTTGAGCTCTGGTGAGGTAGATTTGGCTATCACAACCGCTAAGGTTGATAGC
CATCCCCATGTCATCTTGAGAACATCGCCCACGCTTTGGTATTGTTCGGTGGATTATCAGTTCCAGCCCGGAGAGCCAGT
GCCTTTAGTGGTGATGGATGAGCCCAGTCTGTACCGAGAGATGGCTATTGAGCACTTGACTCAGGCGGGTGTTCCATGGC
GTATTGCCTACGTGGCCTCTTCACTTTCTGCCATTCGAGCGGCAGTAAGAGCAGGGCTTGGGGTGACCGCCAGACCTATA
GAGATGATGAGCCCAGATTTAAGAGTGTTGGGCGAAACTGAAGGGTTGCCTGGTTTACCTGAAACACGGTATGTCTTATG
TAAAGACAAACAGTGTGACAATGAACTGGCACTTGCTATTTTCAGTGCCTTACAAAACAGTTATCAGCACACCATGTCGT
CAGAATCTTCATTAATATTGGATTCCGATTATTTGACAGGTGATGAAGATTAA

Upstream 100 bases:

>100_bases
GGGTACTGTCATACTTAGCGTTGTCCTTTATTGATAACGCTGATACTTAAAACACCAGGGTAGTTTGTAATTAGAATTCA
AAAAAAGTGAAGAATACACT

Downstream 100 bases:

>100_bases
GTAGTCTGTTTTTAATTCATCATCACAAGTCTCTGTATTTTAAGGGGCTTTTTTTTATTTATTTTAGTAAATCCTCTTTT
TTTTCATTTCAGCTTAATTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Pectinase gene transcriptional regulator [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTNANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGLQLLGYARK
ILRFNDEACTSLMYSNMEGSLIIGASDDTADTLLPFLLNRVATLYPRLAIDVRVKRSPFIADMLSSGEVDLAITTAKVDS
HPHVILRTSPTLWYCSVDYQFQPGEPVPLVVMDEPSLYREMAIEHLTQAGVPWRIAYVASSLSAIRAAVRAGLGVTARPI
EMMSPDLRVLGETEGLPGLPETRYVLCKDKQCDNELALAIFSALQNSYQHTMSSESSLILDSDYLTGDED

Sequences:

>Translated_310_residues
MTNANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGLQLLGYARK
ILRFNDEACTSLMYSNMEGSLIIGASDDTADTLLPFLLNRVATLYPRLAIDVRVKRSPFIADMLSSGEVDLAITTAKVDS
HPHVILRTSPTLWYCSVDYQFQPGEPVPLVVMDEPSLYREMAIEHLTQAGVPWRIAYVASSLSAIRAAVRAGLGVTARPI
EMMSPDLRVLGETEGLPGLPETRYVLCKDKQCDNELALAIFSALQNSYQHTMSSESSLILDSDYLTGDED
>Mature_309_residues
TNANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGLQLLGYARKI
LRFNDEACTSLMYSNMEGSLIIGASDDTADTLLPFLLNRVATLYPRLAIDVRVKRSPFIADMLSSGEVDLAITTAKVDSH
PHVILRTSPTLWYCSVDYQFQPGEPVPLVVMDEPSLYREMAIEHLTQAGVPWRIAYVASSLSAIRAAVRAGLGVTARPIE
MMSPDLRVLGETEGLPGLPETRYVLCKDKQCDNELALAIFSALQNSYQHTMSSESSLILDSDYLTGDED

Specific function: Regulates pectinase gene expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=310, Percent_Identity=67.0967741935484, Blast_Score=423, Evalue=1e-120,
Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994962, Length=148, Percent_Identity=31.0810810810811, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=179, Percent_Identity=31.8435754189944, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=23.9837398373984, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787806, Length=149, Percent_Identity=26.8456375838926, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34177; Mature: 34045

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGLQLLGYARKILRFNDEACTSLMYSNMEGSLIIGASDDTADTLLPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
VATLYPRLAIDVRVKRSPFIADMLSSGEVDLAITTAKVDSHPHVILRTSPTLWYCSVDYQ
HHHHCCCCEEEEEECCCCHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCEEEEEEEEE
FQPGEPVPLVVMDEPSLYREMAIEHLTQAGVPWRIAYVASSLSAIRAAVRAGLGVTARPI
ECCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGETEGLPGLPETRYVLCKDKQCDNELALAIFSALQNSYQHTMSSESSLIL
HHCCCCCEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
DSDYLTGDED
ECCCCCCCCC
>Mature Secondary Structure 
TNANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFAR
CCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGRNKLLTEHGLQLLGYARKILRFNDEACTSLMYSNMEGSLIIGASDDTADTLLPFLLNR
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHH
VATLYPRLAIDVRVKRSPFIADMLSSGEVDLAITTAKVDSHPHVILRTSPTLWYCSVDYQ
HHHHCCCCEEEEEECCCCHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCEEEEEEEEE
FQPGEPVPLVVMDEPSLYREMAIEHLTQAGVPWRIAYVASSLSAIRAAVRAGLGVTARPI
ECCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCH
EMMSPDLRVLGETEGLPGLPETRYVLCKDKQCDNELALAIFSALQNSYQHTMSSESSLIL
HHCCCCCEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
DSDYLTGDED
ECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626286 [H]