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The map label for this gene is cscR [H]

Identifier: 218928778

GI number: 218928778

Start: 1867622

End: 1868665

Strand: Reverse

Name: cscR [H]

Synonym: YPO1642

Alternate gene names: 218928778

Gene position: 1868665-1867622 (Counterclockwise)

Preceding gene: 218928779

Following gene: 218928776

Centisome position: 40.15

GC content: 49.14

Gene sequence:

>1044_bases
ATGGTCTCACTGAAAGAAGTGGCAAATCTAGCCTCTGTTTCATTAATGACCGCATCTCGAGCGATTAATAGCCCAGAGCA
ACTGCGGCCGGAAACGTATCAGCGAGTGATGCAGGCGATTGAATCCCTGAATTATGTGCCTGATTTTGCAGCCCGTAAGA
TGCGCGGCCACGCCACCAAAACATCAACCCTGGCAGTACTCGCCTGGGATACGGCGACCACACCGTTCTCAGTTGAAATA
TTGCTCTCCATTGAGTTAACTGCCCGAGAGTTTGGCTGGAACAGCTTTTTAGTGAACCTAACCTCACGCGAGGACAGCCA
ACGGGCGCTTAACCAACTACTCGCCCAACGGCCCGATGGCATTATTTTTACCGCTATGGGGCTACGTCAGGTCACCATTC
CCGAGCGATTTCGGGATAAAAACATTGTTCTCGCTAATTGCGTCAGTGAAAGCCATTCAATTCCTAGCTACATTCCCGAT
GATTTTGATGGTCAATATCAAGCCATGAAGTTGCTGCTGCAACGCGGATATCAGCGGCCTTTGTGTCTTTATCTGCCGGA
GTGTACCTTGGCAGGCAAGGCCCGGCGGGCAGGGGTAGAAAAAGCCTGGCAGGAATCTGCATTACCAACAGAGCAACTCA
ATCAGTGCCATATAGCGTGGGGAGATGAACATTATCAGGATGTCATTCCGCTATTGGAACGCCATTGCCCTAAGGGAAAA
CCTAATTTTGATGTGTTAATTTGCGGCGATGACCGTATCGCATTTTTGGCCTATCAGGTTTTACTGGCCAAAGGTGTGGT
AATTCCACAACAGGTTGCGGTGATCGGCTATGGCGATATGGTTGGTATGGGTGAATTGTATCTACCACCACTGACCACAG
TACAACTCCCCTATTATGATATTGGTCGTCAAGCTGCCCTCCATTTAATAAGAGGACGTGAATCGCGGGCAATACATCGG
TTACCCTGCCCACTACTAGAACGGGGATCCATCCGTGACTCAATGCCTAATAACTGTGTGCCTCTTTTCAGTAAACAGCG
ATAA

Upstream 100 bases:

>100_bases
TTGATAGATAATAGTGATATCACTACAACTATAAAATGAGAGCAACAGCATCACCCATGACAATATAATTACCCTGCCAG
CCTAATCCAGGAGGTACGTA

Downstream 100 bases:

>100_bases
ATAGCGCTCATGGATGCATGCTAAGGACTGATCACTGCGGAGCAGAGTGGCAAGAACGGGGCTGCGTTATACGGGGAAGC
ACGCCATAAATAGTATAAAC

Product: sucrose operon repressor LacI family

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGMGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR

Sequences:

>Translated_347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGMGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR
>Mature_347_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGMGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPNNCVPLFSKQR

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=26.0355029585799, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=26.6467065868263, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787948, Length=348, Percent_Identity=27.5862068965517, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786540, Length=347, Percent_Identity=26.2247838616715, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=24.9230769230769, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=27.9220779220779, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789202, Length=306, Percent_Identity=25.8169934640523, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=22.9607250755287, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38981; Mature: 38981

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGMGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPNNCVPLFSKQR
HHHHHHHHHHHCCCCCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGMGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPNNCVPLFSKQR
HHHHHHHHHHHCCCCCCHHHCCCCHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA