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The map label for this gene is argA [H]

Identifier: 218928191

GI number: 218928191

Start: 1161769

End: 1163094

Strand: Reverse

Name: argA [H]

Synonym: YPO1022

Alternate gene names: 218928191

Gene position: 1163094-1161769 (Counterclockwise)

Preceding gene: 218928195

Following gene: 218928177

Centisome position: 24.99

GC content: 47.74

Gene sequence:

>1326_bases
GTGAAGGAACGTAGTACTGAACTGGTTCAAGGATTTCGCCACTCAGTTCCCTATATCAATGCGCACCGCGGCAAGACATT
TGTTGTCATGCTAGGTGGCGAAGCGATTGAACATGAAAACTTCTCTAGTATCGTCAACGATATAGGCTTATTACATAGCC
TTGGGATCAGATTAGTCGTGGTATACGGTGCCCGACCACAGATTGACAGTAATCTGGCAGATCATAACTACGAACCTATT
TATCATAAACATACCCGAGTGACTGACGCCCGGACTCTGGAGATGGTCAAGCAAGCGGCCGGTTTATTACAACTGGATAT
CACGGCCAGGCTTTCAATGAGTTTGAACAACACCCCACTGCAAGGTGCTCATATCAACGTAGTTAGCGGTAACTTTATCA
TTGCTCAACCGCTAGGTGTGGATGATGGTGTTGATTATTGCCATAGCGGGCGTATCCGGCGCATTGATGAAGAAGCTATT
CATCGCCAATTGGATAATGGCGCTATCGTTTTGCTGGGGCCAGTTGCGGTATCGGTCACAGGTGAAAGCTTTAACCTCAC
ATCAGAGGAAGTTGCAACTCAGTTAGCCATCAAACTGAAAGCGGAGAAAATGATTGGATTCTGCTCATCACAAGGGGTGA
CTGATAGCGAAGGTAATATTATTTCAGAATTGTTCCCAAACGATGCGCAAAAGCGGATTGAAGACCTGGAACAGGATGGG
GATTACAATTCGGGCACAGTACGTTTCTTGCGTGGTGCCGTTAAAGCCTGCCGCAGCGGTGTGCGCCGTAGCCATTTACT
CAGCTATCAGGAAGATGGCGCTCTGATTCAAGAACTCTTCTCCCGTGACGGTATCGGTACCCAGATTGTCATGGAAAGTG
CGGAGCAAGTCCGCCGAGCCACCATCAACGATATCGGCGGTATCTTGGAACTGATTCGCCCATTGGAACAACAAGGGATC
TTGGTGCGCCGTTCACGTGAACAATTAGAGATGGAGATCGATAAGTTTACTATTATTGAACGGGATAATTTAACTATCGC
TTGCGCCGCCCTCTATCCGTTCCCTGATGAACATATTGGTGAAATGGCTTGTGTCGCGGTCCATCCAGATTATCGCAGCT
CCTCCCGGGGAGAAATGCTGCTGAATAGGATAACCAATCAGGCGCGACAAATGGGCCTTAAAAAGCTGTTTGTGCTGACC
ACACGCAGCATTCACTGGTTCCAGGAACGCGGTTTTACACCTGCAGAGGTAGATGTTTTACCTATTCAAAAACAGGAACT
GTATAACTATCAGCGCCGTTCGAAGATCTTACTGGCCGATCTATAG

Upstream 100 bases:

>100_bases
TTATATATATGCAGTTAGTATCAATTTCGTGCTTGCCATCTTGGTCAAAAAAGAATAAAAATACAAAAATACCGAATAAA
AATTCAAAAGAGGATCTGCC

Downstream 100 bases:

>100_bases
CCCCCTATCCCCTTTATACATGCGTAAATGAAATTGGGGGTCAGGGCGGCGGCTACGCTCACGCACTCGAATCACTTATT
GGAAGTACTTATTTGAAACA

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPI
YHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAI
HRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDG
DYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGI
LVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLT
TRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL

Sequences:

>Translated_441_residues
MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPI
YHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAI
HRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDG
DYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGI
LVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLT
TRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL
>Mature_441_residues
MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPI
YHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAI
HRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDG
DYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGI
LVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLT
TRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=441, Percent_Identity=87.0748299319728, Blast_Score=812, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320913, Length=302, Percent_Identity=22.5165562913907, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49356; Mature: 49356

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVV
CCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCEEEEE
VYGARPQIDSNLADHNYEPIYHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPL
EECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCC
QGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDNGAIVLLGPVAVSVT
CCCEEEEEECCEEEEECCCCCCCCHHHHCCCCEECCHHHHHHHCCCCCEEEEEEEEEEEE
GESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDG
CCCCCCCHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCC
DYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
TINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIG
HHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCEEEEEECCCCEEEEEEECCCCHHHHC
EMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLTTRSIHWFQERGFTPAEVDVL
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCCCCCEEEE
PIQKQELYNYQRRSKILLADL
ECCHHHHHHHHHHCEEEEECC
>Mature Secondary Structure
MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVV
CCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHCCEEEEE
VYGARPQIDSNLADHNYEPIYHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPL
EECCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCC
QGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDNGAIVLLGPVAVSVT
CCCEEEEEECCEEEEECCCCCCCCHHHHCCCCEECCHHHHHHHCCCCCEEEEEEEEEEEE
GESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDG
CCCCCCCHHHHHHHHHHHEEHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCC
DYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
TINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIG
HHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHCEEEEEECCCCEEEEEEECCCCHHHHC
EMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLTTRSIHWFQERGFTPAEVDVL
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHCCCCCCCEEEE
PIQKQELYNYQRRSKILLADL
ECCHHHHHHHHHHCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA