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The map label for this gene is epd [H]

Identifier: 218928095

GI number: 218928095

Start: 1012248

End: 1013264

Strand: Reverse

Name: epd [H]

Synonym: YPO0922

Alternate gene names: 218928095

Gene position: 1013264-1012248 (Counterclockwise)

Preceding gene: 218928096

Following gene: 218928094

Centisome position: 21.77

GC content: 49.46

Gene sequence:

>1017_bases
ATGGCAATCCGCATAGCGATAAACGGCTTTGGCCGTATTGGTCGTAGCGTTTTACGCGCGTTGTATGAATCAGGTCGTCG
GGCAGAAATTTCGGTGGTTGCAATCAATGAGTTGGCGAGTGCGGAAGGGATGGCCCATCTGCTGAAGTATGACTCCAGCC
ATGGCCGGTTCGCTTGGGATGTTCGTCAGGAATGTGATTCATTGTATGTCGGGGACGATATTATCCGGCTGATTCATCAG
TCAGAGATTGAGCAGTTACCCTGGAGTGAGTTAGGAATAGATGTGGTTCTGGATTGCAGCGGTGTGTATGGCAGCCGTGA
GGATGGCGAGGCGCATGTAGCCTCCGGTGCAAAAAAAGTGCTGTTTGCCCATCCTGGCGGTCATGATTTGGATGCGACTG
TAGTCTATGGTGTTAATCATCAGGATTTACGGGCAGAGCACCGGATTGTGTCCAACGCCTCCTGTACGACGAACTGCATT
ATTCCTATTATTCAGTTGTTGGATATTGCTTATGGCATTGAATCTGGCACTGTCACTACCATTCATTCGTCAATGAATGA
CCAGCCGGTTATTGATGCTTATCATCAGGATTTACGTCGTACACGAGCAGCCAGCCAATCCATCATTCCTGTGGATACCA
AACTGGCGGCAGGTATTACCCGCATTTTTCCGAAGTTTTGTGACAGGTTTGAGGCTATCTCGGTACGGGTACCGACCATC
AACGTTACGGCTATCGATTTAAGCGTCAGCGTTACTCATCCTGTCGGCGTGGCGGAGGTTAACCAGCTTTTGCAAAAGGC
AGCAAGAGGTGCATTTCGTGGTATAGTTGACTATACGGAATTACCATTGGTGTCGATGGATTTTAACCACGATCCGCACA
GTGCTATTGTCGATGGCACCCAGACGCGGGTGAGTGGGCAGCACCTGATTAAGACGTTGGTATGGTGCGATAATGAATGG
GGCTTCGCCAATAGAATGTTGGATACGACATTGGCGATGGCCAAAAGCGGTTTCTAG

Upstream 100 bases:

>100_bases
GCCAGTATTATGGCCGAATTGTGATAATACGATTAACATCTAAGGACGCGCTACAGTACTCTATGGGGTTGCATGATAAT
AACCAGAGGCAGGGAGTCAC

Downstream 100 bases:

>100_bases
TATGGCGTATTAACGTCTTGTTTTACCGTGATTTACTGCGGTTTTATGGGCGTTAATGTGCAGCTTATGCAACTTTAAAG
AGAATCAACAAGAGGATTCA

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQ
SEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCI
IPIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTI
NVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEW
GFANRMLDTTLAMAKSGF

Sequences:

>Translated_338_residues
MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQ
SEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCI
IPIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTI
NVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEW
GFANRMLDTTLAMAKSGF
>Mature_337_residues
AIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWDVRQECDSLYVGDDIIRLIHQS
EIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKVLFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCII
PIIQLLDIAYGIESGTVTTIHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTIN
VTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGTQTRVSGQHLIKTLVWCDNEWG
FANRMLDTTLAMAKSGF

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=335, Percent_Identity=34.3283582089552, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI7657116, Length=330, Percent_Identity=36.0606060606061, Blast_Score=215, Evalue=4e-56,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=82.5443786982248, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=37.6899696048632, Blast_Score=238, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=343, Percent_Identity=35.8600583090379, Blast_Score=223, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI17534679, Length=343, Percent_Identity=35.5685131195335, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=36.3363363363363, Blast_Score=220, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=36.3363363363363, Blast_Score=220, Evalue=8e-58,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=35.7142857142857, Blast_Score=234, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=36.6071428571429, Blast_Score=233, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=35.1190476190476, Blast_Score=232, Evalue=8e-62,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=34.7560975609756, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=34.7560975609756, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI85725000, Length=328, Percent_Identity=34.7560975609756, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI22023983, Length=328, Percent_Identity=34.7560975609756, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=32.4242424242424, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 37015; Mature: 36884

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00071 GAPDH ; PS00090 NITROGENASE_1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWD
CEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEH
VRQECDSLYVGDDIIRLIHQSEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKV
HHHHHCCEECCHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCCEE
LFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCIIPIIQLLDIAYGIESGTVTT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEECCEE
NVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGT
EEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCCEECCC
QTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAKSGF
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIRIAINGFGRIGRSVLRALYESGRRAEISVVAINELASAEGMAHLLKYDSSHGRFAWD
EEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHCCCCCCCEEEH
VRQECDSLYVGDDIIRLIHQSEIEQLPWSELGIDVVLDCSGVYGSREDGEAHVASGAKKV
HHHHHCCEECCHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCCCCCCCHHHHCCCCEE
LFAHPGGHDLDATVVYGVNHQDLRAEHRIVSNASCTTNCIIPIIQLLDIAYGIESGTVTT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
IHSSMNDQPVIDAYHQDLRRTRAASQSIIPVDTKLAAGITRIFPKFCDRFEAISVRVPTI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHEEEEECCEE
NVTAIDLSVSVTHPVGVAEVNQLLQKAARGAFRGIVDYTELPLVSMDFNHDPHSAIVDGT
EEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEECCCCCCCCCEECCC
QTRVSGQHLIKTLVWCDNEWGFANRMLDTTLAMAKSGF
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA