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The map label for this gene is pgk [H]

Identifier: 218928094

GI number: 218928094

Start: 1010982

End: 1012145

Strand: Reverse

Name: pgk [H]

Synonym: YPO0921

Alternate gene names: 218928094

Gene position: 1012145-1010982 (Counterclockwise)

Preceding gene: 218928095

Following gene: 218928093

Centisome position: 21.75

GC content: 50.95

Gene sequence:

>1164_bases
ATGTCTGTAATTAAGATGACCGATCTGGATCTGGCTGGCAAACGTGTTTTGATCCGTGCGGACCTCAATGTTCCGGTAAA
AGAAGGCAAAGTGACTTCTGATGCGCGTATCCGTGCCTCTCTGCCAACTATCGAAGCGGCATTGAAGCAAGGCGCTAAAG
TAATGGTTACCTCTCACTTGGGTCGCCCGACCGAAGGCGAGTACAACGAAGAGTTCTCCTTACTGCCCGTCGTTAACTAC
CTGAAAGAGAAGTTATCTTCTCCGGTACGTCTGGCGAAGGACTATCTGGACGGCGTTGAAATTGCAGCTGGCGAGTTGGT
TGTTCTGGAAAACGTTCGCTTTAACAAAGGCGAGAAAAAAGACGACGAAGCCCTGTCCAAGAAATATGCCGCACTGTGCG
ATGTTTATGTGATGGATGCTTTTGGTACCGCTCACCGCGCTCAGGCATCGACTCACGGTGTGGGTAAATTTGCCCCTATC
GCTTGCGCCGGCCCGCTGTTGTCAGCAGAGCTGGAAGCATTGGGTAAAGCGCTGGGTAACCCAGCGCGTCCAATGGTTGC
TATCGTTGGTGGCTCTAAAGTTTCAACTAAACTGACCGTGCTGGGCGCGTTGTCTAAAATCGCGGATAAACTGATTGTTG
GCGGTGGTATCGCTAATACCTTCGTTGCGGCTCAAGGCCACAATGTCGGTAAATCTCTGTACGAAGCTGATCTGATCCCA
GAAGCGAAAAGACTGCTAGAGACCTGTGATATCCCTGTTCCTACTGATGTTCGTGTTGCCACTGAGTTCTCTGAAACGGC
AGCCGCGACGCTGAAACCCGCGAACGAAATTAAAGATGACGAACAAATTTTGGATCTGGGCGACGAATCTGCGGAGCGTC
TGGCTGAGATCCTGAAAAATGCCAAAACCATTCTGTGGAATGGTCCGGTTGGTGTGTTCGAGTTCCCTAACTTCCGTAAA
GGGACCGAGATCGTGGCTCGCGCCATTGCAGAAAGCGAAGCATTTTCTATCGCAGGCGGTGGTGATACTTTGGCAGCAAT
CGATCTCTTCGGTATTGCTGACCAAATCTCCTACATTTCTACTGGCGGTGGTGCTTTCCTGGAGTTCGTCGAAGGGAAAA
AACTGCCTGCCGTAGTGATGCTGGAAGAGCGCGCTAAGCAGTAA

Upstream 100 bases:

>100_bases
TGGCGTATTAACGTCTTGTTTTACCGTGATTTACTGCGGTTTTATGGGCGTTAATGTGCAGCTTATGCAACTTTAAAGAG
AATCAACAAGAGGATTCACC

Downstream 100 bases:

>100_bases
TTTGGATAACGGGGGGTCAATGCCGCCCGTTTCGCTATTTCCTCTTGCCATGACGGTGGGCGGATGTAACAGCGAACCTA
TTCACATTTATCTTCGGCCG

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNY
LKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPI
ACAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIP
EAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRK
GTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ

Sequences:

>Translated_387_residues
MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNY
LKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPI
ACAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIP
EAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRK
GTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ
>Mature_386_residues
SVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYL
KEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKKDDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIA
CAGPLLSAELEALGKALGNPARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIPE
AKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKNAKTILWNGPVGVFEFPNFRKG
TEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYISTGGGAFLEFVEGKKLPAVVMLEERAKQ

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505763, Length=412, Percent_Identity=38.1067961165049, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI31543397, Length=412, Percent_Identity=37.1359223300971, Blast_Score=238, Evalue=6e-63,
Organism=Escherichia coli, GI1789294, Length=387, Percent_Identity=88.6304909560724, Blast_Score=699, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17508823, Length=411, Percent_Identity=41.1192214111922, Blast_Score=266, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6319857, Length=417, Percent_Identity=40.0479616306954, Blast_Score=255, Evalue=9e-69,
Organism=Drosophila melanogaster, GI17136394, Length=415, Percent_Identity=40.2409638554217, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24581203, Length=415, Percent_Identity=37.8313253012048, Blast_Score=241, Evalue=9e-64,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41075; Mature: 40943

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHL
CCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCEEEEEECC
GRPTEGEYNEEFSLLPVVNYLKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCC
DDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSAELEALGKALGN
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIP
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCCHHHHHHHHHCCH
EAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKN
HHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCHHHCCCCHHHHHCCCHHHHHHHHHHHC
AKTILWNGPVGVFEFPNFRKGTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYIS
CCEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHEE
TGGGAFLEFVEGKKLPAVVMLEERAKQ
CCCHHHHHHHCCCCCCEEEEEHHHCCC
>Mature Secondary Structure 
SVIKMTDLDLAGKRVLIRADLNVPVKEGKVTSDARIRASLPTIEAALKQGAKVMVTSHL
CEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCEEEEEECC
GRPTEGEYNEEFSLLPVVNYLKEKLSSPVRLAKDYLDGVEIAAGELVVLENVRFNKGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCEECCCCEEEEECCCCCCCCCC
DDEALSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPIACAGPLLSAELEALGKALGN
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PARPMVAIVGGSKVSTKLTVLGALSKIADKLIVGGGIANTFVAAQGHNVGKSLYEADLIP
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHHHHEEEECCCCHHHHHHHHHCCH
EAKRLLETCDIPVPTDVRVATEFSETAAATLKPANEIKDDEQILDLGDESAERLAEILKN
HHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCHHHCCCCHHHHHCCCHHHHHHHHHHHC
AKTILWNGPVGVFEFPNFRKGTEIVARAIAESEAFSIAGGGDTLAAIDLFGIADQISYIS
CCEEEECCCCCCEECCCCCCHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHEE
TGGGAFLEFVEGKKLPAVVMLEERAKQ
CCCHHHHHHHCCCCCCEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA