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The map label for this gene is yicI [C]

Identifier: 218928024

GI number: 218928024

Start: 930057

End: 932435

Strand: Direct

Name: yicI [C]

Synonym: YPO0848

Alternate gene names: 218928024

Gene position: 930057-932435 (Clockwise)

Preceding gene: 218928023

Following gene: 218928026

Centisome position: 19.99

GC content: 50.4

Gene sequence:

>2379_bases
GTGATGAAAACATTAAAAAACTGGCTGTTAATCAATGAGTATCCCGATCACCTTGAACTGCGGGTCGATGACCGTCATAT
CTTTTGTCTGTATGTATTAGAACCAAACTTATGCAGGGTGCTGATTAAACGCGAGGGTGAACTGGCACTGAGCCGCACCT
GGAGTATTGCCCCGCAAGGTGATGTGCCATGGTCAGGCCGCGATCGCCTGAGTCTGGAAGGCTTCTCTCTCCCCGGTTAT
CAATTGGAGAAACATGAACAGCAACTGGTCGTCACGACGGAGTGCCTTCGGGTCACCATCCATCAACCACTGCATCTGAC
ATGGGAATATAAAAACCCGCATGGTGAGTGGCTACCGCTGGCCGCAGACCGGCCAACCAGCGCCTATCTACTCAGCCCTC
AGGGAGAAGCGATTGCTCACTATCAGCGCCGTTATCCCAATGAACAATATTACGGATTGGGCGAAAAAGCCGGTGATCTG
AACCGCGCAGGTCGTCGCTTTGAAATGCGTAATCTGGATGCGATGGGCTATAACGCCGCCAGCACGGACCCGCTCTACAA
ACATATTCCGTTTACTATCACCCGCCGTGATGATGTCAGTTTTGGCCTTTTTTATGACAATCTGAGTAGCTGTTGGCTGG
ATTTAGGCAATGAGATCGATAACTACCATCTGGCCTATCGCCGTTATCAGGCCGAAGCGGGTGACCTTGATTACTATCTG
TTCCTCGGCCCGAAAGTTTTGGATGTCACCAAGGCGTTTGTTCGCCTGACCGGTAAAACCCAATTTGGCCCTAAATGGAG
CCTGGGTTACAGCGGTTCAACCATGCATTACACCGATGCCCCTGATGCTCAGGTACAACTGCAAAAGTTCATTGCATTGT
GTCAGCAGCATGACATCCCTTGCGATTCGTTCCAGCTCTCTTCCGGCTACACCTCCATCAAAAACAAGCGTTATGTCTTT
AACTGGAATTACGACAAAGTGCCGCAACCGAAAGTCATGAGCCAGACGTTCCTACAAGCAGGTATCAAATTAGCCGCCAA
TATAAAACCGTGTTTATTGCAAGATCACCCACAGTATCAACAGGCTGCGGAGCGGGGGCTTTTCATTCGTGACAGCGAAA
CTGATTTACCTGAACGCTCTACATTTTGGGATGATGAAGGCTCCCACCTTGATTTCACCAATCCAGACACCGTGAACTGG
TGGCAAGAGAACGTCACTAAACAGTTATTGGAGATGGGGATCGGTTCTACCTGGAATGATAATAACGAATATGAAGTGTG
GGATGGTGAAGCCCGCTGTAATGGCTTCGGTAAATCTATCGCCATCAAACATATCAGACCGGTAATGCCTTTACTGATGA
TGCGAGCCTCGATGGAAGCACAGAAAGCATTCGCACCAGAAATGCGCCCATACTTGATATCCCGTTCAGGCTGTGCAGGG
ATGCAGCGCTACGCTCAGACCTGGAGTGGTGATAACCGTACCTGTTGGCAAACACTGCGCTATAACATCCGAATGGGGCT
GGGGATGAGCCTGTCAGGGCTGTATAACCTGGGGCATGATGTCGGCGGTTTTTCTGGAGATAAACCGGAACCTGAGCTGT
TTGTCCGCTGGGTACAAAACGGTGTGATGCATCCACGGTTTACCATTCATTCATGGAATGATGACAATACAGTCAACGAG
CCATGGATGTATCCAGCCGCCACGCCGATGATCCGGGATGCGATGGCGTTACGATATCGATTATTGCCCTATTTTTACAC
ATTGCAATGGCAGGCCAGCCATGATGATGAGCCGATGTTGCGCCCTACGTTCCTCGACCACGAACACGATAGCCTCACAT
TTAAAGAGAACGATGACTTTATGCTAGGCCGTGATCTGTTGGTTGCCAGTGTGGTGGACGCTGGGCAACGGCAACGGCAG
ATTTATTTACCTGATAATCAGGTCGGCTGGTATTGCTTCCACAGCGGGCAATGGTATAGCGGTGGGCAGACAATCACATT
GGATGCACCACTAGAGCGATTACCTCTGCTGGTACGCGCGGGGGCAGCCCTGCCGCTATCCCGACGTATCGCCTTTGTTA
ATCCTGAGGCTGATTGTCAGCGCGAATTGGCGCTTTATCCCACTCAAGGTGGCGGGCAATCAAGCGGGATGCTATTTGAG
GACGATGGTGAAAGCCACCGCTGGCAACAAGGCCATGCGCTATGGCTAAATTGGCAGGTCACCACCGATAATCACCGTAT
TGATATCACCTTTAGCCGCACCGGGAACTATCAACCGGCATGGCGTGAACTGACGATTAATTTGCCAACAAATGAAAGTC
GCACGTTATCAATCAACGGTGTCGCAGGTAATACACTGGATTTAACCAAACTGGCCTAA

Upstream 100 bases:

>100_bases
AACTAATGTTGTTACCAAACTGATCTGATTAAGCCATCCATCAGATGCGATTAACCCAGCAGCGGCACTGCCTGTGCTGT
TGCCAGAAAAAAGATGAGCT

Downstream 100 bases:

>100_bases
CCGGCTAATGTTAAATACAAGACGGACTTCCTGATGGAAGCCCGTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGAAC
AGGCAGATCGTAAAGACGCC

Product: putative glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MMKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGY
QLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPHGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDL
NRAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
FLGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVF
NWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVNW
WQENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAG
MQRYAQTWSGDNRTCWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNE
PWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQ
IYLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFE
DDGESHRWQQGHALWLNWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA

Sequences:

>Translated_792_residues
MMKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGY
QLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPHGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDL
NRAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
FLGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVF
NWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVNW
WQENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAG
MQRYAQTWSGDNRTCWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNE
PWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQ
IYLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFE
DDGESHRWQQGHALWLNWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA
>Mature_792_residues
MMKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQGDVPWSGRDRLSLEGFSLPGY
QLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPHGEWLPLAADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDL
NRAGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
FLGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIPCDSFQLSSGYTSIKNKRYVF
NWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQQAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVNW
WQENVTKQLLEMGIGSTWNDNNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAG
MQRYAQTWSGDNRTCWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQNGVMHPRFTIHSWNDDNTVNE
PWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPMLRPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQ
IYLPDNQVGWYCFHSGQWYSGGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFE
DDGESHRWQQGHALWLNWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSINGVAGNTLDLTKLA

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI38202257, Length=658, Percent_Identity=30.0911854103343, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI88900491, Length=658, Percent_Identity=30.0911854103343, Blast_Score=268, Evalue=2e-71,
Organism=Homo sapiens, GI66346737, Length=600, Percent_Identity=29.3333333333333, Blast_Score=242, Evalue=8e-64,
Organism=Homo sapiens, GI119393895, Length=585, Percent_Identity=27.3504273504274, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI119393893, Length=585, Percent_Identity=27.3504273504274, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI119393891, Length=585, Percent_Identity=27.3504273504274, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI221316699, Length=697, Percent_Identity=24.103299856528, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI157364974, Length=660, Percent_Identity=23.4848484848485, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI310115361, Length=266, Percent_Identity=31.5789473684211, Blast_Score=103, Evalue=7e-22,
Organism=Escherichia coli, GI2367256, Length=503, Percent_Identity=25.844930417495, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI2367323, Length=380, Percent_Identity=26.8421052631579, Blast_Score=123, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI71991189, Length=623, Percent_Identity=29.2134831460674, Blast_Score=249, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17560798, Length=638, Percent_Identity=29.4670846394984, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17560800, Length=638, Percent_Identity=29.4670846394984, Blast_Score=244, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI32563849, Length=579, Percent_Identity=24.8704663212435, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71985706, Length=261, Percent_Identity=28.3524904214559, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319706, Length=609, Percent_Identity=26.7651888341544, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24643749, Length=653, Percent_Identity=25.2679938744257, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24643753, Length=653, Percent_Identity=25.2679938744257, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24643751, Length=653, Percent_Identity=25.2679938744257, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24643746, Length=653, Percent_Identity=25.2679938744257, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI21357605, Length=653, Percent_Identity=25.2679938744257, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24650054, Length=372, Percent_Identity=25.5376344086022, Blast_Score=80, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 91158; Mature: 91158

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQG
CCCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCC
DVPWSGRDRLSLEGFSLPGYQLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPHGEWLPL
CCCCCCCCCEEEECCCCCCCHHCCCCCEEEEEEEEEEEEECCCEEEEEEEECCCCCEEEE
AADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLNRAGRRFEMRNLDAMGYNAA
ECCCCCCEEEECCCCCHHHHHHHHCCCCHHCCCCCCCCCHHHCCCEEEECCCCCCCCCCC
STDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
CCCCCHHCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEE
FLGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIP
EECCHHHHHHHHHHEECCCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
CDSFQLSSGYTSIKNKRYVFNWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQ
CCCEEECCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCEEECCCCHHH
QAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVNWWQENVTKQLLEMGIGSTWND
HHHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAG
CCCEEEECCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
MQRYAQTWSGDNRTCWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQN
HHHHHHHHCCCCHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GVMHPRFTIHSWNDDNTVNEPWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPML
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
RPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQIYLPDNQVGWYCFHSGQWYS
CCEECCCCCCCEEEECCCCEEECHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCEEEC
GGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFE
CCEEEEECCCHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEE
DDGESHRWQQGHALWLNWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSING
CCCCCCCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEEC
VAGNTLDLTKLA
CCCCEEEHEECC
>Mature Secondary Structure
MMKTLKNWLLINEYPDHLELRVDDRHIFCLYVLEPNLCRVLIKREGELALSRTWSIAPQG
CCCCCCCCEEEECCCCCEEEEECCCEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCC
DVPWSGRDRLSLEGFSLPGYQLEKHEQQLVVTTECLRVTIHQPLHLTWEYKNPHGEWLPL
CCCCCCCCCEEEECCCCCCCHHCCCCCEEEEEEEEEEEEECCCEEEEEEEECCCCCEEEE
AADRPTSAYLLSPQGEAIAHYQRRYPNEQYYGLGEKAGDLNRAGRRFEMRNLDAMGYNAA
ECCCCCCEEEECCCCCHHHHHHHHCCCCHHCCCCCCCCCHHHCCCEEEECCCCCCCCCCC
STDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
CCCCCHHCCCEEEEECCCCEEEEEHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEE
FLGPKVLDVTKAFVRLTGKTQFGPKWSLGYSGSTMHYTDAPDAQVQLQKFIALCQQHDIP
EECCHHHHHHHHHHEECCCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCC
CDSFQLSSGYTSIKNKRYVFNWNYDKVPQPKVMSQTFLQAGIKLAANIKPCLLQDHPQYQ
CCCEEECCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCCCEEECCCCHHH
QAAERGLFIRDSETDLPERSTFWDDEGSHLDFTNPDTVNWWQENVTKQLLEMGIGSTWND
HHHHCCEEEECCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NNEYEVWDGEARCNGFGKSIAIKHIRPVMPLLMMRASMEAQKAFAPEMRPYLISRSGCAG
CCCEEEECCCHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHH
MQRYAQTWSGDNRTCWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPEPELFVRWVQN
HHHHHHHHCCCCHHHHHHHHEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
GVMHPRFTIHSWNDDNTVNEPWMYPAATPMIRDAMALRYRLLPYFYTLQWQASHDDEPML
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
RPTFLDHEHDSLTFKENDDFMLGRDLLVASVVDAGQRQRQIYLPDNQVGWYCFHSGQWYS
CCEECCCCCCCEEEECCCCEEECHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCEEEC
GGQTITLDAPLERLPLLVRAGAALPLSRRIAFVNPEADCQRELALYPTQGGGQSSGMLFE
CCEEEEECCCHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCEEEE
DDGESHRWQQGHALWLNWQVTTDNHRIDITFSRTGNYQPAWRELTINLPTNESRTLSING
CCCCCCCCCCCCEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEEC
VAGNTLDLTKLA
CCCCEEEHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]