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The map label for this gene is lysM

Identifier: 15920372

GI number: 15920372

Start: 216525

End: 216947

Strand: Reverse

Name: lysM

Synonym: ST0193

Alternate gene names: 15920372

Gene position: 216947-216525 (Counterclockwise)

Preceding gene: 15920373

Following gene: 15920371

Centisome position: 8.05

GC content: 30.02

Gene sequence:

>423_bases
ATGGCGGATGTAGATGAAAGTGATTTAAAAATTCTTGAAATATTAAGGAAAAATGCAAGAACTCCATACACTAGTATAGC
TAAAGAGCTCAAAATTAGTGAAGCTGCAGTAAGGAAAAGGATTGAAAAACTAATAAAAATGGGTGTAATTAAGAGATTCA
CAATTGATTATGAGCTAGAAAATGAAATAAGAGCTATAGTTATGGTAAAAACTAATCCACAAATCCCAACACCAGAAATT
TCTAAAAAAATAATAAAGATTCAAGGAGTAGAATTTGTATATGAGACAACTGGGGATTATGACATTTTAACAGTAGTTAG
GGGTACTAACATCTCCTCAATTAATAAAACAATAGATGATATAAGAAGCCTTCAAGGAGTACTAAGTACAAATAGTACAA
TAGTTCTTAGAGTCTGGTTTTAA

Upstream 100 bases:

>100_bases
AAACTATTGAAAATGGAGTTAAAAAAGTAATAATCTCCTCGGGTCTTGTGCAAGACCCAATTTCAAATGCATTACAATTA
AGGGGAACGGTGATCATGTA

Downstream 100 bases:

>100_bases
AATCGAACCATTTATTTTCATAAAAGCTTATCAACTACTTACTTTTTATGATATATTTGATCCAAAAATGGTAGTCCTAA
AGTGCCCAGTATGTAATGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MADVDESDLKILEILRKNARTPYTSIAKELKISEAAVRKRIEKLIKMGVIKRFTIDYELENEIRAIVMVKTNPQIPTPEI
SKKIIKIQGVEFVYETTGDYDILTVVRGTNISSINKTIDDIRSLQGVLSTNSTIVLRVWF

Sequences:

>Translated_140_residues
MADVDESDLKILEILRKNARTPYTSIAKELKISEAAVRKRIEKLIKMGVIKRFTIDYELENEIRAIVMVKTNPQIPTPEI
SKKIIKIQGVEFVYETTGDYDILTVVRGTNISSINKTIDDIRSLQGVLSTNSTIVLRVWF
>Mature_139_residues
ADVDESDLKILEILRKNARTPYTSIAKELKISEAAVRKRIEKLIKMGVIKRFTIDYELENEIRAIVMVKTNPQIPTPEIS
KKIIKIQGVEFVYETTGDYDILTVVRGTNISSINKTIDDIRSLQGVLSTNSTIVLRVWF

Specific function: In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the diaminopimelate pathway

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYSM_SULTO (Q976J7)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376041.1
- ProteinModelPortal:   Q976J7
- SMR:   Q976J7
- GeneID:   1458078
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0193
- NMPDR:   fig|273063.1.peg.209
- HOGENOM:   HBG740878
- OMA:   DYELENE
- ProtClustDB:   CLSK802584
- BioCyc:   STOK273063:ST0193-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00033
- SMART:   SM00344

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11; SSF54909 Dimer_A_B_barrel

EC number: NA

Molecular weight: Translated: 15969; Mature: 15838

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00519 HTH_ASNC_1; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVDESDLKILEILRKNARTPYTSIAKELKISEAAVRKRIEKLIKMGVIKRFTIDYELE
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
NEIRAIVMVKTNPQIPTPEISKKIIKIQGVEFVYETTGDYDILTVVRGTNISSINKTIDD
CCEEEEEEEECCCCCCCHHHHHHEEEEECCEEEEECCCCEEEEEEEECCCHHHHHHHHHH
IRSLQGVLSTNSTIVLRVWF
HHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure 
ADVDESDLKILEILRKNARTPYTSIAKELKISEAAVRKRIEKLIKMGVIKRFTIDYELE
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
NEIRAIVMVKTNPQIPTPEISKKIIKIQGVEFVYETTGDYDILTVVRGTNISSINKTIDD
CCEEEEEEEECCCCCCCHHHHHHEEEEECCEEEEECCCCEEEEEEEECCCHHHHHHHHHH
IRSLQGVLSTNSTIVLRVWF
HHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479