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The map label for this gene is argB

Identifier: 15920373

GI number: 15920373

Start: 216947

End: 217732

Strand: Reverse

Name: argB

Synonym: ST0194

Alternate gene names: 15920373

Gene position: 217732-216947 (Counterclockwise)

Preceding gene: 161751104

Following gene: 15920372

Centisome position: 8.08

GC content: 31.93

Gene sequence:

>786_bases
ATGATAGTTATAAAAGCCGGAGGAAGAGTAATAAAAAATAATTTAGATGGTATTATTGAAAGTTTATCTAATGTAGGAGA
ACAAGCTATATTTGTTCATGGTGGTGGAGACCAGGTAACTGAGACTTCTAAGAAACTAGGAATAGAACCAGTATTTGTAA
CTTCACCAGAAGGAATAAGAAGTAGATATACATCTAAAGAAGAGTTAGAAGTTTTTATAATGGTTATGAGTTTAATTTCA
AGACAAATAGTATCAAAATTAGCTTATAAAAAGAAAGTAATTTCACTAACTGGTGCTGATGGTAACTCTGTAATTGCAGA
GAGAAAGAAAAAAATAATAATAATAGATGAAAGAGGAAGAAAAAGAATAGTTGATGGTGGTTATACTGGGAAAATAAAGA
AAGTGGATTCATTAGTAATCTCAGATTTGTTAAAGAGTTTTGATCTTCTAGTTTTTGCTCCACTGGCATACGATCCAGAA
GAAAAAACATTACTTAATGTTGATGGAGATCAAATGGCTTTTGCAATTGCTACTGCTATGAAAGCCGATACTTTAATACT
TCTAACTGATGTTGAAGGAGTTTTAGTTGATGGAAAAGTAATAAATAAGCTCACATCTAAAGAGGCTAAAGAATTATCTA
AAAGAATAGGGCCCGGTATGAACAGAAAACTATTAATGGCCGGAGAAACTATTGAAAATGGAGTTAAAAAAGTAATAATC
TCCTCGGGTCTTGTGCAAGACCCAATTTCAAATGCATTACAATTAAGGGGAACGGTGATCATGTAA

Upstream 100 bases:

>100_bases
ATGAAAGGTGCTGCTGGTCAAGCAGTACAAGCTTTTAACATATCAAGAGGTTTTGAAGAAGATGAGGGTTTAAGAATACC
TCCTCTGAGGCCTGCTTAAA

Downstream 100 bases:

>100_bases
TGGCGGATGTAGATGAAAGTGATTTAAAAATTCTTGAAATATTAAGGAAAAATGCAAGAACTCCATACACTAGTATAGCT
AAAGAGCTCAAAATTAGTGA

Product: acetylglutamate/acetylaminoadipate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate/N-acetyl-L-aminoadipate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIRSRYTSKEELEVFIMVMSLIS
RQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGRKRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPE
EKTLLNVDGDQMAFAIATAMKADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVII
SSGLVQDPISNALQLRGTVIM

Sequences:

>Translated_261_residues
MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIRSRYTSKEELEVFIMVMSLIS
RQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGRKRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPE
EKTLLNVDGDQMAFAIATAMKADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVII
SSGLVQDPISNALQLRGTVIM
>Mature_261_residues
MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIRSRYTSKEELEVFIMVMSLIS
RQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGRKRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPE
EKTLLNVDGDQMAFAIATAMKADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVII
SSGLVQDPISNALQLRGTVIM

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

None

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_SULTO (Q976J6)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376042.1
- ProteinModelPortal:   Q976J6
- SMR:   Q976J6
- GeneID:   1458079
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0194
- NMPDR:   fig|273063.1.peg.210
- HOGENOM:   HBG497643
- OMA:   YLPVLTP
- ProtClustDB:   PRK14058
- BioCyc:   STOK273063:ST0194-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_A
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 28326; Mature: 28326

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: BINDING 62-62 BINDING 166-166

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIR
CEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCHHHH
SRYTSKEELEVFIMVMSLISRQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCEEEEEECCCC
KRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPEEKTLLNVDGDQMAFAIATAM
EEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCHHHHHHHHHH
KADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVII
CCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
SSGLVQDPISNALQLRGTVIM
HCCCHHHHHHHHHHHCCEEEC
>Mature Secondary Structure
MIVIKAGGRVIKNNLDGIIESLSNVGEQAIFVHGGGDQVTETSKKLGIEPVFVTSPEGIR
CEEECCCCEEEHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEECCHHHH
SRYTSKEELEVFIMVMSLISRQIVSKLAYKKKVISLTGADGNSVIAERKKKIIIIDERGR
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHCCCCEEEEEECCCC
KRIVDGGYTGKIKKVDSLVISDLLKSFDLLVFAPLAYDPEEKTLLNVDGDQMAFAIATAM
EEEECCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEECCCCHHHHHHHHHH
KADTLILLTDVEGVLVDGKVINKLTSKEAKELSKRIGPGMNRKLLMAGETIENGVKKVII
CCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
SSGLVQDPISNALQLRGTVIM
HCCCHHHHHHHHHHHCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479