The gene/protein map for NC_003106 is currently unavailable.
Definition Sulfolobus tokodaii str. 7 chromosome, complete genome.
Accession NC_003106
Length 2,694,756

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The map label for this gene is argD

Identifier: 15920369

GI number: 15920369

Start: 214273

End: 215436

Strand: Reverse

Name: argD

Synonym: ST0191

Alternate gene names: 15920369

Gene position: 215436-214273 (Counterclockwise)

Preceding gene: 15920370

Following gene: 15920368

Centisome position: 7.99

GC content: 35.31

Gene sequence:

>1164_bases
ATGAAGTTCATTCAACTTTATGGAGATAGAGGACTAACTATAGTAAAAGGAGAGGGTCAGTACGTATGGGATATTAGTGG
AACAAAATACTTAGACCTTCATACGGGAATTGGTGTAGCCTTTTTAGGACACAGAAACAGAAGGGTTATAGAATATTTAT
CAAGACAAATGGAAAATATTATGACTTTATCTACTTCATTTTCTACCCCTATCAGAGACGAAATGCTAAAAGAACTAGAC
CCTTTAAAACCAGATAAGATGGATAATATTATTTTATTAAATAGCGGTACTGAAGCTGTTGAAGCGGCTCTGAAAACTGC
TAGGAAAATAACTGGTAGGAAAAAAATAATTGCTTTCAAAAATTCATTTCACGGAAGAACAGCAGGTTCCCTTTCAGTTA
CATGGAATAAAAGATATAGAGAACCTTTTGAGCCATTAATGTCACCAGTACAATTTCTAACTTATAATAATATAGATGAA
TTAAAGAACATAGATGAACAAACAGCTGCTGTAATAGTTGAACCAATTCAAGGTGAATCCGGAGTAATTCCAGCTAATGA
AGACTTCATGAAAGCTTTAAGAGAACAAACACAAAAAGTAGGTGCTTTGTTAGTAGTTGACGAAGTTCAAACCGGTTTTG
GAAGAACTGGAAAAGTATGGGCTTATCAACATTATGGTATTATTCCAGATTTGTTAACAGCAGGAAAGGCAATTGGGGGA
GGTTTTCCAGTTAGTGCTTTATTTCTGCCAGATTGGATAGCGGAAAAATTGGAAGAGGGTGATCATGGTAGTACTTATGG
AGGAAATCCAATGGCTATGGCTGCAGTTACTGCGGCATCGAAAGTTTTAAAGGAAGACAATGTAGTAGAACAAGCAAGCA
TTAAAGGAGAGATATTTAAGAAAATTCTCCGGGAAAAACTCAGTGATTTGAAATCAGTGAGGGAAATTAGAGGTAAAGGC
TTAATGATAGGTATTGAAATTAGATTTCCACCAGCAATTGCATTAAAAGTTATGCAAGATGAAAGAGTTTTAGCCTTAAA
AGCTGGATCAACAGTTATAAGATTTCTTGCACCATACATGATTACACAAAGCGATATGGAGGAAGCATCAAATGCAGCTA
GAAAAGGAATTATCGAGACGGAAAATAAAAGAGCTATTACTTGA

Upstream 100 bases:

>100_bases
ATGAAGTAAATGGAGTGCCAGAATACAAAAATACTGTAAGAGTCAATAATTTTAACGTATCAGAGTATTTAATTAGAAAA
ATTGAAGAGTGGATTAAAAA

Downstream 100 bases:

>100_bases
AATACTTTCAATTTATACTCCTTCTGGCGAAGAGGAAAGAGCTAAAGATTTTTTTGAAAAAGTCTCAAAGGAATTTAATC
TTAATCTAGAAATTTCTAAA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKFIQLYGDRGLTIVKGEGQYVWDISGTKYLDLHTGIGVAFLGHRNRRVIEYLSRQMENIMTLSTSFSTPIRDEMLKELD
PLKPDKMDNIILLNSGTEAVEAALKTARKITGRKKIIAFKNSFHGRTAGSLSVTWNKRYREPFEPLMSPVQFLTYNNIDE
LKNIDEQTAAVIVEPIQGESGVIPANEDFMKALREQTQKVGALLVVDEVQTGFGRTGKVWAYQHYGIIPDLLTAGKAIGG
GFPVSALFLPDWIAEKLEEGDHGSTYGGNPMAMAAVTAASKVLKEDNVVEQASIKGEIFKKILREKLSDLKSVREIRGKG
LMIGIEIRFPPAIALKVMQDERVLALKAGSTVIRFLAPYMITQSDMEEASNAARKGIIETENKRAIT

Sequences:

>Translated_387_residues
MKFIQLYGDRGLTIVKGEGQYVWDISGTKYLDLHTGIGVAFLGHRNRRVIEYLSRQMENIMTLSTSFSTPIRDEMLKELD
PLKPDKMDNIILLNSGTEAVEAALKTARKITGRKKIIAFKNSFHGRTAGSLSVTWNKRYREPFEPLMSPVQFLTYNNIDE
LKNIDEQTAAVIVEPIQGESGVIPANEDFMKALREQTQKVGALLVVDEVQTGFGRTGKVWAYQHYGIIPDLLTAGKAIGG
GFPVSALFLPDWIAEKLEEGDHGSTYGGNPMAMAAVTAASKVLKEDNVVEQASIKGEIFKKILREKLSDLKSVREIRGKG
LMIGIEIRFPPAIALKVMQDERVLALKAGSTVIRFLAPYMITQSDMEEASNAARKGIIETENKRAIT
>Mature_387_residues
MKFIQLYGDRGLTIVKGEGQYVWDISGTKYLDLHTGIGVAFLGHRNRRVIEYLSRQMENIMTLSTSFSTPIRDEMLKELD
PLKPDKMDNIILLNSGTEAVEAALKTARKITGRKKIIAFKNSFHGRTAGSLSVTWNKRYREPFEPLMSPVQFLTYNNIDE
LKNIDEQTAAVIVEPIQGESGVIPANEDFMKALREQTQKVGALLVVDEVQTGFGRTGKVWAYQHYGIIPDLLTAGKAIGG
GFPVSALFLPDWIAEKLEEGDHGSTYGGNPMAMAAVTAASKVLKEDNVVEQASIKGEIFKKILREKLSDLKSVREIRGKG
LMIGIEIRFPPAIALKVMQDERVLALKAGSTVIRFLAPYMITQSDMEEASNAARKGIIETENKRAIT

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=32.5396825396825, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI13994255, Length=436, Percent_Identity=28.6697247706422, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=35.2159468438538, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI37574042, Length=394, Percent_Identity=28.1725888324873, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI226442705, Length=394, Percent_Identity=27.1573604060914, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI24119277, Length=344, Percent_Identity=27.3255813953488, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442709, Length=364, Percent_Identity=27.4725274725275, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI188536080, Length=379, Percent_Identity=25.3298153034301, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI38679950, Length=379, Percent_Identity=25.3298153034301, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI38679946, Length=379, Percent_Identity=25.3298153034301, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=36.7724867724868, Blast_Score=247, Evalue=7e-67,
Organism=Escherichia coli, GI1788044, Length=374, Percent_Identity=37.1657754010695, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI145693181, Length=378, Percent_Identity=36.5079365079365, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1787560, Length=383, Percent_Identity=31.5926892950392, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1789016, Length=333, Percent_Identity=30.6306306306306, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786349, Length=311, Percent_Identity=34.0836012861736, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786991, Length=403, Percent_Identity=28.5359801488834, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=381, Percent_Identity=30.7086614173228, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=429, Percent_Identity=29.8368298368298, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=32.3420074349442, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=363, Percent_Identity=30.8539944903581, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17541228, Length=383, Percent_Identity=28.4595300261097, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71981843, Length=172, Percent_Identity=25, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=36.6925064599483, Blast_Score=242, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6323470, Length=396, Percent_Identity=31.0606060606061, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6321456, Length=367, Percent_Identity=28.0653950953678, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=325, Percent_Identity=27.0769230769231, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=33.1578947368421, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=29.7872340425532, Blast_Score=174, Evalue=8e-44,
Organism=Drosophila melanogaster, GI161085790, Length=412, Percent_Identity=29.3689320388349, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI21356575, Length=410, Percent_Identity=27.5609756097561, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI281366494, Length=384, Percent_Identity=24.21875, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24667139, Length=384, Percent_Identity=24.21875, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24667143, Length=384, Percent_Identity=24.21875, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ARGD_SULTO (Q976K0)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376038.1
- ProteinModelPortal:   Q976K0
- SMR:   Q976K0
- GeneID:   1458075
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0191
- NMPDR:   fig|273063.1.peg.206
- HOGENOM:   HBG725944
- OMA:   SLSITWN
- ProtClustDB:   CLSK883609
- BioCyc:   STOK273063:ST0191-MONOMER
- BRENDA:   2.6.1.11
- GO:   GO:0005737
- HAMAP:   MF_01107
- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF19
- TIGRFAMs:   TIGR00707

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.11

Molecular weight: Translated: 42935; Mature: 42935

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: BINDING 123-123 BINDING 126-126 BINDING 264-264 BINDING 265-265

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKFIQLYGDRGLTIVKGEGQYVWDISGTKYLDLHTGIGVAFLGHRNRRVIEYLSRQMENI
CCEEEEECCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHH
MTLSTSFSTPIRDEMLKELDPLKPDKMDNIILLNSGTEAVEAALKTARKITGRKKIIAFK
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEE
NSFHGRTAGSLSVTWNKRYREPFEPLMSPVQFLTYNNIDELKNIDEQTAAVIVEPIQGES
CCCCCCCCCEEEEEECHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEECCCCC
GVIPANEDFMKALREQTQKVGALLVVDEVQTGFGRTGKVWAYQHYGIIPDLLTAGKAIGG
CCCCCCHHHHHHHHHHHHHHCEEEEEECHHCCCCCCCCEEEEECCCCCHHHHHCCHHCCC
GFPVSALFLPDWIAEKLEEGDHGSTYGGNPMAMAAVTAASKVLKEDNVVEQASIKGEIFK
CCCHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KILREKLSDLKSVREIRGKGLMIGIEIRFPPAIALKVMQDERVLALKAGSTVIRFLAPYM
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCEEEEEECCHHHHHHHHHHH
ITQSDMEEASNAARKGIIETENKRAIT
HHHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure
MKFIQLYGDRGLTIVKGEGQYVWDISGTKYLDLHTGIGVAFLGHRNRRVIEYLSRQMENI
CCEEEEECCCCEEEEECCCCEEEECCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHH
MTLSTSFSTPIRDEMLKELDPLKPDKMDNIILLNSGTEAVEAALKTARKITGRKKIIAFK
HHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEE
NSFHGRTAGSLSVTWNKRYREPFEPLMSPVQFLTYNNIDELKNIDEQTAAVIVEPIQGES
CCCCCCCCCEEEEEECHHCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHEEEEEECCCCC
GVIPANEDFMKALREQTQKVGALLVVDEVQTGFGRTGKVWAYQHYGIIPDLLTAGKAIGG
CCCCCCHHHHHHHHHHHHHHCEEEEEECHHCCCCCCCCEEEEECCCCCHHHHHCCHHCCC
GFPVSALFLPDWIAEKLEEGDHGSTYGGNPMAMAAVTAASKVLKEDNVVEQASIKGEIFK
CCCHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KILREKLSDLKSVREIRGKGLMIGIEIRFPPAIALKVMQDERVLALKAGSTVIRFLAPYM
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCEEEEEECCHHHHHHHHHHH
ITQSDMEEASNAARKGIIETENKRAIT
HHHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479