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The map label for this gene is lysK

Identifier: 15920368

GI number: 15920368

Start: 213285

End: 214325

Strand: Reverse

Name: lysK

Synonym: ST0190

Alternate gene names: 15920368

Gene position: 214325-213285 (Counterclockwise)

Preceding gene: 15920369

Following gene: 15920367

Centisome position: 7.95

GC content: 30.64

Gene sequence:

>1041_bases
ATGCAGCTAGAAAAGGAATTATCGAGACGGAAAATAAAAGAGCTATTACTTGAAATACTTTCAATTTATACTCCTTCTGG
CGAAGAGGAAAGAGCTAAAGATTTTTTTGAAAAAGTCTCAAAGGAATTTAATCTTAATCTAGAAATTTCTAAATCTAAGT
CATATTTCCTAGGAAAAGGGGATATACTCTTAGCATCACATATAGATACAGTTCCAGGATTTATACAGCCTAAAATAGAA
GGAGAAGTTATATATGGTAGGGGGGCTGTTGACGCAAAAGGTCCTTTGATTGCTATGCTTTTGGCAACTTATATATTAAA
TGAAAAAGGGTATAAAGTTCAATTTGCTGCACTAGCAGATGAAGAAGGAAAAAGTAAGGGCGCAAGGGAATTAGCTAATA
GTGGTATTAGGTACAATTATATTATCATAGGGGAACCCAGTAATACTTTAGATGTTATAGTGGAATATAGGGGAGTATTG
CATTTAGATATATTATGTAGAGGAAATTCTCAGCATTCTTCTTCATCTAAAGAGAATTTGATAGTTGACTTATCGAAAAA
AATTCTAGAAATATATAGAGAACCAAGTAACTATGAGAATTTTTCTATAGTACCTACCATAATAAAATCTGGTGATTATA
TAAATATGACACCTTCAGAAGGGTATTTACATCTAGATATAAGATACTCGATTAAAAACTCTAAGGATGAGATTCTAGCT
CTTATTCATAATGAGTTTAAAACATGTGATATAAAAATAGTAGAAGATATAGAACCAGTGAAAGTTGATGTAAATAGTAA
TATTGTTAAAGCAGTTATGCGAGGCATAATAAAGCAAGGGTATAAGCCAAAACTAGCTAGAAAAGCAGGGACTAGTGATA
TGAATATATTAAAAAATATAGCAAAAGAAATAGTAACCTATGGACCTGGGAATTCTACGTTAGAACACACAAATAATGAA
AAGATTTCTATCGATGAAATATTTATAGCTTTAACAACTTATATCAATGCGATAGAAGAATTATGTTTAAAGAAAAAGTA
G

Upstream 100 bases:

>100_bases
ATGCAAGATGAAAGAGTTTTAGCCTTAAAAGCTGGATCAACAGTTATAAGATTTCTTGCACCATACATGATTACACAAAG
CGATATGGAGGAAGCATCAA

Downstream 100 bases:

>100_bases
GGAAGATTATACTATATCCAGTCTATAAGTTCTATGAAAAAATTTTATGGAATGAGATAAAAAATGGTCCATTTCCTCAA
CATGTTGGAATTATTCCAGA

Product: acetyl-lysine deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQLEKELSRRKIKELLLEILSIYTPSGEEERAKDFFEKVSKEFNLNLEISKSKSYFLGKGDILLASHIDTVPGFIQPKIE
GEVIYGRGAVDAKGPLIAMLLATYILNEKGYKVQFAALADEEGKSKGARELANSGIRYNYIIIGEPSNTLDVIVEYRGVL
HLDILCRGNSQHSSSSKENLIVDLSKKILEIYREPSNYENFSIVPTIIKSGDYINMTPSEGYLHLDIRYSIKNSKDEILA
LIHNEFKTCDIKIVEDIEPVKVDVNSNIVKAVMRGIIKQGYKPKLARKAGTSDMNILKNIAKEIVTYGPGNSTLEHTNNE
KISIDEIFIALTTYINAIEELCLKKK

Sequences:

>Translated_346_residues
MQLEKELSRRKIKELLLEILSIYTPSGEEERAKDFFEKVSKEFNLNLEISKSKSYFLGKGDILLASHIDTVPGFIQPKIE
GEVIYGRGAVDAKGPLIAMLLATYILNEKGYKVQFAALADEEGKSKGARELANSGIRYNYIIIGEPSNTLDVIVEYRGVL
HLDILCRGNSQHSSSSKENLIVDLSKKILEIYREPSNYENFSIVPTIIKSGDYINMTPSEGYLHLDIRYSIKNSKDEILA
LIHNEFKTCDIKIVEDIEPVKVDVNSNIVKAVMRGIIKQGYKPKLARKAGTSDMNILKNIAKEIVTYGPGNSTLEHTNNE
KISIDEIFIALTTYINAIEELCLKKK
>Mature_346_residues
MQLEKELSRRKIKELLLEILSIYTPSGEEERAKDFFEKVSKEFNLNLEISKSKSYFLGKGDILLASHIDTVPGFIQPKIE
GEVIYGRGAVDAKGPLIAMLLATYILNEKGYKVQFAALADEEGKSKGARELANSGIRYNYIIIGEPSNTLDVIVEYRGVL
HLDILCRGNSQHSSSSKENLIVDLSKKILEIYREPSNYENFSIVPTIIKSGDYINMTPSEGYLHLDIRYSIKNSKDEILA
LIHNEFKTCDIKIVEDIEPVKVDVNSNIVKAVMRGIIKQGYKPKLARKAGTSDMNILKNIAKEIVTYGPGNSTLEHTNNE
KISIDEIFIALTTYINAIEELCLKKK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fifth step. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. LysK subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LYSK_SULTO (Q976K1)

Other databases:

- EMBL:   BA000023
- RefSeq:   NP_376037.1
- ProteinModelPortal:   Q976K1
- GeneID:   1458074
- GenomeReviews:   BA000023_GR
- KEGG:   sto:ST0190
- NMPDR:   fig|273063.1.peg.205
- HOGENOM:   HBG728841
- OMA:   SVDAKGP
- ProtClustDB:   PRK00466
- BioCyc:   STOK273063:ST0190-MONOMER
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_01120
- InterPro:   IPR001261
- InterPro:   IPR010175
- InterPro:   IPR002933
- InterPro:   IPR011650
- TIGRFAMs:   TIGR01902

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: 3.5.1.-

Molecular weight: Translated: 38908; Mature: 38908

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 69-69 ACT_SITE 121-121

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEKELSRRKIKELLLEILSIYTPSGEEERAKDFFEKVSKEFNLNLEISKSKSYFLGKG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCC
DILLASHIDTVPGFIQPKIEGEVIYGRGAVDAKGPLIAMLLATYILNEKGYKVQFAALAD
CEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
EEGKSKGARELANSGIRYNYIIIGEPSNTLDVIVEYRGVLHLDILCRGNSQHSSSSKENL
CCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHEECCCEEEEEEEEECCCCCCCCCCCCE
IVDLSKKILEIYREPSNYENFSIVPTIIKSGDYINMTPSEGYLHLDIRYSIKNSKDEILA
EEHHHHHHHHHHCCCCCCCCCEEEEHHCCCCCEEEECCCCCEEEEEEEEEECCCHHHHHH
LIHNEFKTCDIKIVEDIEPVKVDVNSNIVKAVMRGIIKQGYKPKLARKAGTSDMNILKNI
HHHCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHH
AKEIVTYGPGNSTLEHTNNEKISIDEIFIALTTYINAIEELCLKKK
HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLEKELSRRKIKELLLEILSIYTPSGEEERAKDFFEKVSKEFNLNLEISKSKSYFLGKG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCEEECCC
DILLASHIDTVPGFIQPKIEGEVIYGRGAVDAKGPLIAMLLATYILNEKGYKVQFAALAD
CEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECC
EEGKSKGARELANSGIRYNYIIIGEPSNTLDVIVEYRGVLHLDILCRGNSQHSSSSKENL
CCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHEECCCEEEEEEEEECCCCCCCCCCCCE
IVDLSKKILEIYREPSNYENFSIVPTIIKSGDYINMTPSEGYLHLDIRYSIKNSKDEILA
EEHHHHHHHHHHCCCCCCCCCEEEEHHCCCCCEEEECCCCCEEEEEEEEEECCCHHHHHH
LIHNEFKTCDIKIVEDIEPVKVDVNSNIVKAVMRGIIKQGYKPKLARKAGTSDMNILKNI
HHHCCCCEEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHH
AKEIVTYGPGNSTLEHTNNEKISIDEIFIALTTYINAIEELCLKKK
HHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479