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The map label for this gene is mcpA [H]

Identifier: 159185172

GI number: 159185172

Start: 2333791

End: 2335740

Strand: Reverse

Name: mcpA [H]

Synonym: Atu2360

Alternate gene names: 159185172

Gene position: 2335740-2333791 (Counterclockwise)

Preceding gene: 15889635

Following gene: 15889633

Centisome position: 82.2

GC content: 60.62

Gene sequence:

>1950_bases
GTGTCTTTTTTTAAAAATGCCAGCATCCGTACCAAAATCCTGTCGCTCATTTTGCCGCTCTGCATCGTCGGTCTTGGCGC
CGCCGCCTTCATGGCCACACGCTATAAGGAATCCGATGCACTCTATTCCGAATTCATCGGCAGCGACAATGCTGCGTTGG
TCGAGCTTGCGCGGGCAAACCGCAATCTCATCGGCCTTGCTTATGGCGCGTATCAGGTCATGGCCTATGACGCGAATGCT
GCGGAAATCAACGTCGCCAGGCAGGCCTACATCGCCAGCAAACGCGAGCTTCTCGAGCGGCTCGACAACGTCAAGGCCGT
GTTTCCCGAGGAGCGCGCCGCCGTCGACGTCTTGATTGCGCAATCCCAGTCCATCGCGGAAATCACCGATAAGGCCGTCG
AGCTTGGAATGGCGAACAAGAACGCGGAATCTGCCGTGCAACTCGTCAAGGCGGACGCCTCGATTCAGATCATGTCGGCC
ACCATAACGATGTTGCTGGACAAGCTTGCCAAAGGGGTGGCTAGTGGCAGCGGTGATCTGAGTGACCAAACCAATTCAAC
GATCCTCACCTCGCTCGTCGTGGTGGGTGTTGTCTTTGCAGTTGGTATCATCCTGACACTGTTTGTGGCGTCAAGCGGCA
TCACCACACCGATTGCCCGGTTGCGCGAGCGCATGGTGTCGCTTGCCGGTGGCGAGACGGCGGCTGAGATCGACGGCGTG
GAGCGGAAGGACGAAGTTGGCCAGATGGCGGTCGCGGTTCAGGTGTTCCGCGAGAATGCGATCGAGCGCATCCGTCTCGA
GCAGGAAACCGAGGCCAACAGGTCGATGTCGGAAAAGGACCGCATCGAGCGCGAGCAGCAGAAGGCAAGGGAAGCCGCGG
ACGTCAAGTTTGCCGTCGATAATCTCGCGGCCGGTCTTTCGAAGCTTTCGGACGGCGATGTTTCCTATCGCATCGACCAG
CCGTTCACGGCAACGCTCGACGGCGTGCGCAACGACTTCAACATGTCGGCCGAAAAGCTGCAATCGGCCTTGACCCGGGT
TGCCCAGAATGCCGGCGGCATCGGCGCAGGTGCAAACGAGATCAAGTCGGCTGCCGATGACCTGGCCAAGCGCACCGAAC
AGCAGGCTGCTGCCGTGGAGGAAACTGCCGCAGCTCTGGAGGAAATCACCACGACGGTGCGGGACTCCACCAAACGTGCA
CAGGAGGCGGGCCAGATCGTCAGCCGCGCCAAGGCGGGTGCCGAACAATCCGGCGAAGTGGTGCGCCGCGCCGTGATCGC
GATGGAGCAGATTTCCAAATCCGCCAACGAGATCAGCAACATCATCGGCGTGATCGATGAGATCGCCTTCCAGACCAATC
TTCTGGCGTTGAATGCCGGTGTCGAGGCAGCAAGGGCGGGCGAGGCGGGCAAGGGTTTTGCCGTCGTCGCACAGGAAGTG
CGCGAGCTTGCGCAACGGTCCGCCAGTGCGGCCAAGGAGATCAAGGCGCTGATCACCACCTCGAATGATCAGGTGCAGCA
GGGCGTGCAGCTGGTGGGCGACACCGGCAAGGCGCTGGCGACGATCGTCTCGGAGGTGCAGGAAATCAACCGGCACGTCG
TTTCCATCGTGGAATCCGCGCAGGAACAGTCTTCCGGCCTGCAGCAGATCAATACGGCTGTGAACCAGATGGATCAGGAC
ACGCAGAAGAATGCGGCCATGGTGGAAGAGACCAATGCCGCAAGCCATAGCCTCGCCAAGGAAGTGGCATCGCTCAACCA
GCTGCTCTCGCAGTTCAGACTGGCTGAGGGTGCCTATCAGCAGAAGAGCCAGCCGGCTCCGGTGCGCAGCGCCGCCGGCA
GCGACAGATCGGTGGCATCTCCCGTGCGGGCGCTTGGCCGCAAGCTTGCTTCGGCATTCTCGGGCAATGCCGCGCTGGAT
ACATCGAAGGGTGACTGGCAGGAGTTCTGA

Upstream 100 bases:

>100_bases
CTGATGAGGCCTTGATGATGAAGGCTTTCGACGTGCAATGTCATTTTTGCCGAACACCTCCGGCACGGGAAAGGAGCGGC
GTCCATTTCAGGAGCTTCCC

Downstream 100 bases:

>100_bases
TCGCCTCTTGTCGTTCGGGCGGTTATCCGCCCGATGACGGCAGACCGGTGGTTTCGTCCGCCGGCAGGCTTGGAGACATA
CCGCGCAGGTTTTATTCCTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MSFFKNASIRTKILSLILPLCIVGLGAAAFMATRYKESDALYSEFIGSDNAALVELARANRNLIGLAYGAYQVMAYDANA
AEINVARQAYIASKRELLERLDNVKAVFPEERAAVDVLIAQSQSIAEITDKAVELGMANKNAESAVQLVKADASIQIMSA
TITMLLDKLAKGVASGSGDLSDQTNSTILTSLVVVGVVFAVGIILTLFVASSGITTPIARLRERMVSLAGGETAAEIDGV
ERKDEVGQMAVAVQVFRENAIERIRLEQETEANRSMSEKDRIEREQQKAREAADVKFAVDNLAAGLSKLSDGDVSYRIDQ
PFTATLDGVRNDFNMSAEKLQSALTRVAQNAGGIGAGANEIKSAADDLAKRTEQQAAAVEETAAALEEITTTVRDSTKRA
QEAGQIVSRAKAGAEQSGEVVRRAVIAMEQISKSANEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEV
RELAQRSASAAKEIKALITTSNDQVQQGVQLVGDTGKALATIVSEVQEINRHVVSIVESAQEQSSGLQQINTAVNQMDQD
TQKNAAMVEETNAASHSLAKEVASLNQLLSQFRLAEGAYQQKSQPAPVRSAAGSDRSVASPVRALGRKLASAFSGNAALD
TSKGDWQEF

Sequences:

>Translated_649_residues
MSFFKNASIRTKILSLILPLCIVGLGAAAFMATRYKESDALYSEFIGSDNAALVELARANRNLIGLAYGAYQVMAYDANA
AEINVARQAYIASKRELLERLDNVKAVFPEERAAVDVLIAQSQSIAEITDKAVELGMANKNAESAVQLVKADASIQIMSA
TITMLLDKLAKGVASGSGDLSDQTNSTILTSLVVVGVVFAVGIILTLFVASSGITTPIARLRERMVSLAGGETAAEIDGV
ERKDEVGQMAVAVQVFRENAIERIRLEQETEANRSMSEKDRIEREQQKAREAADVKFAVDNLAAGLSKLSDGDVSYRIDQ
PFTATLDGVRNDFNMSAEKLQSALTRVAQNAGGIGAGANEIKSAADDLAKRTEQQAAAVEETAAALEEITTTVRDSTKRA
QEAGQIVSRAKAGAEQSGEVVRRAVIAMEQISKSANEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEV
RELAQRSASAAKEIKALITTSNDQVQQGVQLVGDTGKALATIVSEVQEINRHVVSIVESAQEQSSGLQQINTAVNQMDQD
TQKNAAMVEETNAASHSLAKEVASLNQLLSQFRLAEGAYQQKSQPAPVRSAAGSDRSVASPVRALGRKLASAFSGNAALD
TSKGDWQEF
>Mature_648_residues
SFFKNASIRTKILSLILPLCIVGLGAAAFMATRYKESDALYSEFIGSDNAALVELARANRNLIGLAYGAYQVMAYDANAA
EINVARQAYIASKRELLERLDNVKAVFPEERAAVDVLIAQSQSIAEITDKAVELGMANKNAESAVQLVKADASIQIMSAT
ITMLLDKLAKGVASGSGDLSDQTNSTILTSLVVVGVVFAVGIILTLFVASSGITTPIARLRERMVSLAGGETAAEIDGVE
RKDEVGQMAVAVQVFRENAIERIRLEQETEANRSMSEKDRIEREQQKAREAADVKFAVDNLAAGLSKLSDGDVSYRIDQP
FTATLDGVRNDFNMSAEKLQSALTRVAQNAGGIGAGANEIKSAADDLAKRTEQQAAAVEETAAALEEITTTVRDSTKRAQ
EAGQIVSRAKAGAEQSGEVVRRAVIAMEQISKSANEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVR
ELAQRSASAAKEIKALITTSNDQVQQGVQLVGDTGKALATIVSEVQEINRHVVSIVESAQEQSSGLQQINTAVNQMDQDT
QKNAAMVEETNAASHSLAKEVASLNQLLSQFRLAEGAYQQKSQPAPVRSAAGSDRSVASPVRALGRKLASAFSGNAALDT
SKGDWQEF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=44.9180327868852, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1787690, Length=296, Percent_Identity=41.8918918918919, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1788194, Length=258, Percent_Identity=45.7364341085271, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=43.0817610062893, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1789453, Length=215, Percent_Identity=41.3953488372093, Blast_Score=156, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68882; Mature: 68751

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFKNASIRTKILSLILPLCIVGLGAAAFMATRYKESDALYSEFIGSDNAALVELARAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
RNLIGLAYGAYQVMAYDANAAEINVARQAYIASKRELLERLDNVKAVFPEERAAVDVLIA
CCEEEEEEHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QSQSIAEITDKAVELGMANKNAESAVQLVKADASIQIMSATITMLLDKLAKGVASGSGDL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
SDQTNSTILTSLVVVGVVFAVGIILTLFVASSGITTPIARLRERMVSLAGGETAAEIDGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
ERKDEVGQMAVAVQVFRENAIERIRLEQETEANRSMSEKDRIEREQQKAREAADVKFAVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NLAAGLSKLSDGDVSYRIDQPFTATLDGVRNDFNMSAEKLQSALTRVAQNAGGIGAGANE
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
IKSAADDLAKRTEQQAAAVEETAAALEEITTTVRDSTKRAQEAGQIVSRAKAGAEQSGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VRRAVIAMEQISKSANEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHH
RELAQRSASAAKEIKALITTSNDQVQQGVQLVGDTGKALATIVSEVQEINRHVVSIVESA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEQSSGLQQINTAVNQMDQDTQKNAAMVEETNAASHSLAKEVASLNQLLSQFRLAEGAYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSQPAPVRSAAGSDRSVASPVRALGRKLASAFSGNAALDTSKGDWQEF
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFFKNASIRTKILSLILPLCIVGLGAAAFMATRYKESDALYSEFIGSDNAALVELARAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCC
RNLIGLAYGAYQVMAYDANAAEINVARQAYIASKRELLERLDNVKAVFPEERAAVDVLIA
CCEEEEEEHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
QSQSIAEITDKAVELGMANKNAESAVQLVKADASIQIMSATITMLLDKLAKGVASGSGDL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
SDQTNSTILTSLVVVGVVFAVGIILTLFVASSGITTPIARLRERMVSLAGGETAAEIDGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCC
ERKDEVGQMAVAVQVFRENAIERIRLEQETEANRSMSEKDRIEREQQKAREAADVKFAVD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
NLAAGLSKLSDGDVSYRIDQPFTATLDGVRNDFNMSAEKLQSALTRVAQNAGGIGAGANE
HHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
IKSAADDLAKRTEQQAAAVEETAAALEEITTTVRDSTKRAQEAGQIVSRAKAGAEQSGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
VRRAVIAMEQISKSANEISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHH
RELAQRSASAAKEIKALITTSNDQVQQGVQLVGDTGKALATIVSEVQEINRHVVSIVESA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QEQSSGLQQINTAVNQMDQDTQKNAAMVEETNAASHSLAKEVASLNQLLSQFRLAEGAYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKSQPAPVRSAAGSDRSVASPVRALGRKLASAFSGNAALDTSKGDWQEF
CCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]