Click here to switch to the map view.

The map label for this gene is suhB [H]

Identifier: 159184949

GI number: 159184949

Start: 1836844

End: 1837671

Strand: Reverse

Name: suhB [H]

Synonym: Atu1857

Alternate gene names: 159184949

Gene position: 1837671-1836844 (Counterclockwise)

Preceding gene: 159184950

Following gene: 15889157

Centisome position: 64.67

GC content: 58.57

Gene sequence:

>828_bases
ATGAGCCTTTCCGATAAAGATATCGAATTCCTCGTTTCCACCGTCGCCGCTGCCGGCGCACAGGAAATCCTGCCCCGCTT
CCGAAACCTGAGCGCCGGCGCCATCTCCGAAAAGACCTCCGCCATCGATCTCGTCACCGAGGCAGATGTTCTGGCGGAAA
AGGCGATCACCGCCGCGCTACTCGAACGGTTTCCGAAGGCTCATATCGTCGGTGAAGAGACCTATGAGGCGGACCCTTCC
GTCATTCCAGCCCTTGCCGATGCGCCGCTTGCCTTCGTGATCGATCCGATCGACGGTACTTTCAATTATGCTTCCGGCTT
TCCCGCTTTCGGCACGCTGCTTGCTGTCACGGTCAAGGGTGAGACGGTGGCGGGCATCATCCACGATCCTGTCATGGGCG
ACACCATAGTTGCGCTCAAAGGTGAGGGGGCTTACCTCCACCGCAAGAACGGCTCGCAGGCGAAGCTCAAGGTCACGGAT
CCCGCGCCACTGTCCGAGATGGTCGGCATCTTTTCCTGGCGTCACAGCCATGAGGATCGCCGTCCTGTCATTGCCGCCAA
TCTGGCGAAGATAAAAATGTCGCTTTCGATCAATTGTTCGGCGCATGAATATTGGCTCGTCTCGGCAGGCAAGCTGCATT
TCATAGGCCATGAAAATCTGGCGCCGTGGGATCATCTTGCCGGCGTGCTGGTTCATCAGGAGGCGGGTGGCTATACGGCC
CGTTTCGACAATACGCCTTACCGGCCCGGCCAGACGGCAGGCGGTATCCTGTCAGCGCCGGACAAGGAAAGCTGGAAGAT
GCTGCGGCGGGAAATCGTCGCCTTATAA

Upstream 100 bases:

>100_bases
GACCCGAAGCTTTTTGATTTTTCCGCGCTTGCTGTCACCGGCGCGTCACCTGAAGAGCGTAGGGAGGCCAGCCCTCCCTG
ATGAAGAAGTGCCCCGCGCC

Downstream 100 bases:

>100_bases
GATTGATACTCAGATAGAAGGATATCGCCCATGGCTCTCGAACTCGACATCGCCTCTCTCGCCAATGCGCTTCAGGAAGC
GGCGGCAGTGGAAATCCTGC

Product: inositol monophosphatase family protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSLSDKDIEFLVSTVAAAGAQEILPRFRNLSAGAISEKTSAIDLVTEADVLAEKAITAALLERFPKAHIVGEETYEADPS
VIPALADAPLAFVIDPIDGTFNYASGFPAFGTLLAVTVKGETVAGIIHDPVMGDTIVALKGEGAYLHRKNGSQAKLKVTD
PAPLSEMVGIFSWRHSHEDRRPVIAANLAKIKMSLSINCSAHEYWLVSAGKLHFIGHENLAPWDHLAGVLVHQEAGGYTA
RFDNTPYRPGQTAGGILSAPDKESWKMLRREIVAL

Sequences:

>Translated_275_residues
MSLSDKDIEFLVSTVAAAGAQEILPRFRNLSAGAISEKTSAIDLVTEADVLAEKAITAALLERFPKAHIVGEETYEADPS
VIPALADAPLAFVIDPIDGTFNYASGFPAFGTLLAVTVKGETVAGIIHDPVMGDTIVALKGEGAYLHRKNGSQAKLKVTD
PAPLSEMVGIFSWRHSHEDRRPVIAANLAKIKMSLSINCSAHEYWLVSAGKLHFIGHENLAPWDHLAGVLVHQEAGGYTA
RFDNTPYRPGQTAGGILSAPDKESWKMLRREIVAL
>Mature_274_residues
SLSDKDIEFLVSTVAAAGAQEILPRFRNLSAGAISEKTSAIDLVTEADVLAEKAITAALLERFPKAHIVGEETYEADPSV
IPALADAPLAFVIDPIDGTFNYASGFPAFGTLLAVTVKGETVAGIIHDPVMGDTIVALKGEGAYLHRKNGSQAKLKVTDP
APLSEMVGIFSWRHSHEDRRPVIAANLAKIKMSLSINCSAHEYWLVSAGKLHFIGHENLAPWDHLAGVLVHQEAGGYTAR
FDNTPYRPGQTAGGILSAPDKESWKMLRREIVAL

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=215, Percent_Identity=27.4418604651163, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI5031789, Length=215, Percent_Identity=27.4418604651163, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI221625507, Length=149, Percent_Identity=30.2013422818792, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7657236, Length=132, Percent_Identity=34.8484848484849, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI116812595, Length=142, Percent_Identity=33.0985915492958, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788882, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=223, Percent_Identity=26.457399103139, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321836, Length=209, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=209, Percent_Identity=27.7511961722488, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664926, Length=214, Percent_Identity=31.7757009345794, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357957, Length=240, Percent_Identity=28.75, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24664918, Length=243, Percent_Identity=25.9259259259259, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI21357303, Length=243, Percent_Identity=30.8641975308642, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24664922, Length=203, Percent_Identity=31.0344827586207, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357329, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29533; Mature: 29402

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDKDIEFLVSTVAAAGAQEILPRFRNLSAGAISEKTSAIDLVTEADVLAEKAITAAL
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
LERFPKAHIVGEETYEADPSVIPALADAPLAFVIDPIDGTFNYASGFPAFGTLLAVTVKG
HHHCCCCEECCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECC
ETVAGIIHDPVMGDTIVALKGEGAYLHRKNGSQAKLKVTDPAPLSEMVGIFSWRHSHEDR
CEEEEEEECCCCCCEEEEEECCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
RPVIAANLAKIKMSLSINCSAHEYWLVSAGKLHFIGHENLAPWDHLAGVLVHQEAGGYTA
CCEEEEEEEEEEEEEEEECCCCEEEEEECCEEEEEECCCCCCHHHHCEEEEEECCCCEEE
RFDNTPYRPGQTAGGILSAPDKESWKMLRREIVAL
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLSDKDIEFLVSTVAAAGAQEILPRFRNLSAGAISEKTSAIDLVTEADVLAEKAITAAL
CCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHH
LERFPKAHIVGEETYEADPSVIPALADAPLAFVIDPIDGTFNYASGFPAFGTLLAVTVKG
HHHCCCCEECCCCCCCCCCCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECC
ETVAGIIHDPVMGDTIVALKGEGAYLHRKNGSQAKLKVTDPAPLSEMVGIFSWRHSHEDR
CEEEEEEECCCCCCEEEEEECCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
RPVIAANLAKIKMSLSINCSAHEYWLVSAGKLHFIGHENLAPWDHLAGVLVHQEAGGYTA
CCEEEEEEEEEEEEEEEECCCCEEEEEECCEEEEEECCCCCCHHHHCEEEEEECCCCEEE
RFDNTPYRPGQTAGGILSAPDKESWKMLRREIVAL
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]