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The map label for this gene is cdd [H]

Identifier: 159184173

GI number: 159184173

Start: 134652

End: 135056

Strand: Direct

Name: cdd [H]

Synonym: Atu0130

Alternate gene names: 159184173

Gene position: 134652-135056 (Clockwise)

Preceding gene: 15887484

Following gene: 15887486

Centisome position: 4.74

GC content: 57.28

Gene sequence:

>405_bases
ATGTCCTCCGACCCAAAATCCCATGCCCTGTTCGAGGCGGCGGTGGAGGCCATGGCCTTCGCTTATGCGCCCTATTCGAA
ATTTCCGGTCGGCGCAGCGATCCGCGCTGAAGATGGAAAAATCTATACGGGCGCCAATATCGAGAATATCTCCTTCCCTC
AAGGCTGGTGCGCGGAGCCATCAGCCATCAGCGCCATGATCATGGGCGGAGCGAAAAAGATCAGCGAAGTGGCCGTCATC
GCTGAAAAGCTGCCGCTCTGCTCTCCCTGCGGCGGTTGCCGGCAGAAGATTGCGGAATTCGCCACGCCGGAGACGAAGAT
TTATCTTTGCGACGAAACTGGCGTCCAGAAAGTCATGACCATGGAAGAGCTTTTGCCCTCCGTCTTCAAGACCGAGCTGC
CCTGA

Upstream 100 bases:

>100_bases
ATGCCCTATATCCTGACCTGCATCCTGCTTGCCGGTTTCATCGGCGTTGCCAAGCCCCCCAAGGCCGGTGGCGTTGCCTA
TGCGAAGGAGCGTTAAACCC

Downstream 100 bases:

>100_bases
TGACGGACGGTCTGATCGATATTCTGGTGGAGCGCCTGAACGGCCTCATGCCGCGCGTCGCCATAGTTCTGGGGTCTGGC
CTTGGTTCGCTGGTGGAAGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MSSDPKSHALFEAAVEAMAFAYAPYSKFPVGAAIRAEDGKIYTGANIENISFPQGWCAEPSAISAMIMGGAKKISEVAVI
AEKLPLCSPCGGCRQKIAEFATPETKIYLCDETGVQKVMTMEELLPSVFKTELP

Sequences:

>Translated_134_residues
MSSDPKSHALFEAAVEAMAFAYAPYSKFPVGAAIRAEDGKIYTGANIENISFPQGWCAEPSAISAMIMGGAKKISEVAVI
AEKLPLCSPCGGCRQKIAEFATPETKIYLCDETGVQKVMTMEELLPSVFKTELP
>Mature_133_residues
SSDPKSHALFEAAVEAMAFAYAPYSKFPVGAAIRAEDGKIYTGANIENISFPQGWCAEPSAISAMIMGGAKKISEVAVIA
EKLPLCSPCGGCRQKIAEFATPETKIYLCDETGVQKVMTMEELLPSVFKTELP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=126, Percent_Identity=42.0634920634921, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551074, Length=121, Percent_Identity=42.9752066115703, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=123, Percent_Identity=39.0243902439024, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=42.6356589147287, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920920, Length=128, Percent_Identity=43.75, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24582744, Length=101, Percent_Identity=50.4950495049505, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582741, Length=133, Percent_Identity=38.3458646616541, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14341; Mature: 14210

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDPKSHALFEAAVEAMAFAYAPYSKFPVGAAIRAEDGKIYTGANIENISFPQGWCAEP
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCH
SAISAMIMGGAKKISEVAVIAEKLPLCSPCGGCRQKIAEFATPETKIYLCDETGVQKVMT
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
MEELLPSVFKTELP
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SSDPKSHALFEAAVEAMAFAYAPYSKFPVGAAIRAEDGKIYTGANIENISFPQGWCAEP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCH
SAISAMIMGGAKKISEVAVIAEKLPLCSPCGGCRQKIAEFATPETKIYLCDETGVQKVMT
HHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHH
MEELLPSVFKTELP
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]